Tight junction protein claudin-2 promotes self-renewal of human colorectal cancer stem-like cells S Paquet-Fifield, SL Koh, L Cheng, LM Beyit, C Shembrey, C Mølck, ... Cancer research 78 (11), 2925-2938, 2018 | 69 | 2018 |
Surgical stress response and promotion of metastasis in colorectal cancer: a complex and heterogeneous process C Behrenbruch, C Shembrey, S Paquet-Fifield, C Mølck, HJ Cho, ... Clinical & experimental metastasis 35, 333-345, 2018 | 67 | 2018 |
Serine biosynthesis is a metabolic vulnerability in flt3-itd–driven acute myeloid leukemia S Bjelosevic, E Gruber, A Newbold, C Shembrey, JR Devlin, SJ Hogg, ... Cancer discovery 11 (6), 1582-1599, 2021 | 42 | 2021 |
Impact of tumor and immunological heterogeneity on the anti-cancer immune response C Shembrey, ND Huntington, F Hollande Cancers 11 (9), 1217, 2019 | 40 | 2019 |
Laminin 521 enhances self-renewal via STAT3 activation and promotes tumor progression in colorectal cancer Y Qin, C Shembrey, J Smith, S Paquet-Fifield, C Behrenbruch, LM Beyit, ... Cancer letters 476, 161-169, 2020 | 26 | 2020 |
NKG7 enhances CD8+ T cell synapse efficiency to limit inflammation EJ Lelliott, KM Ramsbottom, MR Dowling, C Shembrey, T Noori, ... Frontiers in immunology 13, 931630, 2022 | 9 | 2022 |
Longitudinal monitoring of intra-tumoural heterogeneity using optical barcoding of patient-derived colorectal tumour models C Shembrey, J Smith, M Grandin, N Williams, HJ Cho, C Mølck, ... Cancers 14 (3), 581, 2022 | 7 | 2022 |
Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer C Behrenbruch, M Foroutan, P Lind, J Smith, M Grandin, B Cooper, ... BioRxiv, 2021.02. 04.429849, 2021 | 6 | 2021 |
A new natural killer cell-specific gene signature predicting recurrence in colorectal cancer patients C Shembrey, M Foroutan, F Hollande Frontiers in Immunology 13, 1011247, 2023 | 3 | 2023 |
A new highly-specific Natural Killer cell-specific gene signature predicting recurrence in colorectal cancer patients C Shembrey, C Behrenbruch, BPT Loveday, AG Heriot, M Foroutan, ... bioRxiv, 2022.04. 29.489868, 2022 | 2 | 2022 |
Phenotypic Consequences of SLC25A40-ABCB1 Fusions beyond Drug Resistance in High-Grade Serous Ovarian Cancer KI Pishas, KJ Cowley, A Pandey, T Hoang, JA Beach, J Luu, R Vary, ... Cancers 13 (22), 5644, 2021 | 2 | 2021 |
Reprogramming of serine metabolism is an actionable vulnerability in FLT3-ITD driven acute myeloid leukaemia S Bjelosevic, E Gruber, A Newbold, LM Kats, C Shembrey, TC Abrehart, ... bioRxiv, 2020.05. 26.116392, 2020 | 2 | 2020 |
Molecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision C Shembrey, R Yang, J Casan, W Hu, T Sadras, K Prasad, J Shortt, ... bioRxiv, 2023.09. 26.557083, 2023 | 1 | 2023 |
The protective role of Natural Killer (NK) cell tumour immunosurveillance has long been recognised in colorectal cancer (CRC). However, as most patients show limited intra … C Shembrey, M Foroutan Advances in mathematical and computational oncology, volume III, 242, 2023 | | 2023 |
3002–REPROGRAMMING OF SERINE METABOLISM IS A METABOLIC VULNERABILITY IN FMS-LIKE TYROSINE KINASE 3 (FLT3) MUTANT ACUTE MYELOID LEUKAEMIA S Bjelosevic, E Gruber, A Newbold, C Shembrey, T Abrehart, I Todorovski, ... Experimental Hematology 88, S37-S38, 2020 | | 2020 |
Optical barcoding highlights novel characteristics of treatment resistant cells in metastatic colorectal cancer F Hollande, C Behrenbruch, C Shembrey, PX Qiao, D Ferrari, B Thomson, ... ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 14, 147-147, 2018 | | 2018 |