High-resolution comparative modeling with RosettaCM Y Song, F DiMaio, RYR Wang, D Kim, C Miles, TJ Brunette, J Thompson, ... Structure 21 (10), 1735-1742, 2013 | 1168 | 2013 |
Exploring the repeat protein universe through computational protein design TJ Brunette, F Parmeggiani, PS Huang, G Bhabha, DC Ekiert, ... Nature 528 (7583), 580-584, 2015 | 299 | 2015 |
Programmable design of orthogonal protein heterodimers Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ... Nature 565 (7737), 106-111, 2019 | 183 | 2019 |
Computational design of self-assembling cyclic protein homo-oligomers JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ... Nature chemistry 9 (4), 353-360, 2017 | 159 | 2017 |
Computational design of transmembrane pores C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ... Nature 585 (7823), 129-134, 2020 | 144 | 2020 |
Multi-input chemical control of protein dimerization for programming graded cellular responses GW Foight, Z Wang, CT Wei, P Jr Greisen, KM Warner, ... Nature biotechnology 37 (10), 1209-1216, 2019 | 80 | 2019 |
Design of multi-scale protein complexes by hierarchical building block fusion Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ... Nature Communications 12 (1), 2294, 2021 | 60 | 2021 |
Coordinated teams of reactive mobile platforms J Sweeney, TJ Brunette, Y Yang, R Grupen Proceedings 2002 IEEE International Conference on Robotics and Automation …, 2002 | 60 | 2002 |
Guiding conformation space search with an all‐atom energy potential TJ Brunette, O Brock Proteins: Structure, Function, and Bioinformatics 73 (4), 958-972, 2008 | 53 | 2008 |
Modular repeat protein sculpting using rigid helical junctions TJ Brunette, MJ Bick, JM Hansen, CM Chow, JM Kollman, D Baker Proceedings of the National Academy of Sciences 117 (16), 8870-8875, 2020 | 48 | 2020 |
Improving protein structure prediction with model-based search TJ Brunette, O Brock Bioinformatics 21 (suppl_1), i66-i74, 2005 | 31 | 2005 |
De novo design of modular peptide-binding proteins by superhelical matching K Wu, H Bai, YT Chang, R Redler, KE McNally, W Sheffler, TJ Brunette, ... Nature 616 (7957), 581-589, 2023 | 27 | 2023 |
De novo design of obligate ABC-type heterotrimeric proteins S Bermeo, A Favor, YT Chang, A Norris, SE Boyken, Y Hsia, HK Haddox, ... Nature Structural & Molecular Biology 29 (12), 1266-1276, 2022 | 19 | 2022 |
De novo design of protein homodimers containing tunable symmetric protein pockets DR Hicks, MA Kennedy, KA Thompson, M DeWitt, B Coventry, A Kang, ... Proceedings of the National Academy of Sciences 119 (30), e2113400119, 2022 | 16 | 2022 |
Elfin: An algorithm for the computational design of custom three-dimensional structures from modular repeat protein building blocks CT Yeh, TJ Brunette, D Baker, S McIntosh-Smith, F Parmeggiani Journal of Structural Biology 201 (2), 100-107, 2018 | 16 | 2018 |
Massively parallel determination and modeling of endonuclease substrate specificity SB Thyme, Y Song, TJ Brunette, MD Szeto, L Kusak, P Bradley, D Baker Nucleic acids research 42 (22), 13839-13852, 2014 | 16 | 2014 |
Precisely patterned nanofibres made from extendable protein multiplexes NP Bethel, AJ Borst, F Parmeggiani, MJ Bick, TJ Brunette, H Nguyen, ... Nature Chemistry 15 (12), 1664-1671, 2023 | 9 | 2023 |
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ... bioRxiv, 2020.07. 27.221333, 2020 | 8 | 2020 |
Blueprinting extendable nanomaterials with standardized protein blocks TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ... Nature 627 (8005), 898-904, 2024 | 7 | 2024 |
De novo design of buttressed loops for sculpting protein functions H Jiang, KM Jude, K Wu, J Fallas, G Ueda, TJ Brunette, DR Hicks, H Pyles, ... Nature Chemical Biology, 1-7, 2024 | 3 | 2024 |