Complex immune dysregulation in COVID-19 patients with severe respiratory failure EJ Giamarellos-Bourboulis, MG Netea, N Rovina, K Akinosoglou, ... Cell host & microbe 27 (6), 992-1000. e3, 2020 | 2156 | 2020 |
mTOR-and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity SC Cheng, J Quintin, RA Cramer, KM Shepardson, S Saeed, V Kumar, ... science 345 (6204), 1250684, 2014 | 1846 | 2014 |
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity S Saeed, J Quintin, HHD Kerstens, NA Rao, A Aghajanirefah, F Matarese, ... science 345 (6204), 1251086, 2014 | 1528 | 2014 |
Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes J Quintin, S Saeed, JHA Martens, EJ Giamarellos-Bourboulis, DC Ifrim, ... Cell host & microbe 12 (2), 223-232, 2012 | 1117 | 2012 |
Azithromycin: mechanisms of action and their relevance for clinical applications MJ Parnham, VE Haber, EJ Giamarellos-Bourboulis, G Perletti, ... Pharmacology & therapeutics 143 (2), 225-245, 2014 | 701 | 2014 |
A guiding map for inflammation MG Netea, F Balkwill, M Chonchol, F Cominelli, MY Donath, ... Nature immunology 18 (8), 826-831, 2017 | 692 | 2017 |
Two phase 3 trials of adalimumab for hidradenitis suppurativa AB Kimball, MM Okun, DA Williams, AB Gottlieb, KA Papp, CC Zouboulis, ... New England Journal of Medicine 375 (5), 422-434, 2016 | 676 | 2016 |
Swarm learning for decentralized and confidential clinical machine learning S Warnat-Herresthal, H Schultze, KL Shastry, S Manamohan, ... Nature 594 (7862), 265-270, 2021 | 588 | 2021 |
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ... Nature immunology 17 (4), 406-413, 2016 | 520 | 2016 |
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity MF Osuchowski, MS Winkler, T Skirecki, S Cajander, M Shankar-Hari, ... The Lancet Respiratory Medicine 9 (6), 622-642, 2021 | 491 | 2021 |
Trained immunity: a tool for reducing susceptibility to and the severity of SARS-CoV-2 infection MG Netea, EJ Giamarellos-Bourboulis, J Domínguez-Andrés, N Curtis, ... Cell 181 (5), 969-977, 2020 | 462 | 2020 |
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial E Kyriazopoulou, G Poulakou, H Milionis, S Metallidis, G Adamis, ... Nature medicine 27 (10), 1752-1760, 2021 | 460 | 2021 |
What causes hidradenitis suppurativa? L Ralf Paus, H Kurzen, I Kurokawa, GBE Jemec, L Emtestam, K Sellheyer, ... Experimental dermatology 17 (5), 455-456, 2008 | 455 | 2008 |
Carrier systems for the local delivery of antibiotics in bone infections K Kanellakopoulou, EJ Giamarellos-Bourboulis Drugs 59, 1223-1232, 2000 | 409 | 2000 |
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans B Ferwerda, MBB McCall, S Alonso, EJ Giamarellos-Bourboulis, ... Proceedings of the National Academy of Sciences 104 (42), 16645-16650, 2007 | 408 | 2007 |
Effect and safety of meropenem–vaborbactam versus best-available therapy in patients with carbapenem-resistant Enterobacteriaceae infections: the TANGO II randomized clinical trial RG Wunderink, EJ Giamarellos-Bourboulis, G Rahav, AJ Mathers, ... Infectious diseases and therapy 7 (4), 439-455, 2018 | 388 | 2018 |
Development and validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a novel dynamic scoring system to assess HS severity CC Zouboulis, T Tzellos, A Kyrgidis, GBE Jemec, FG Bechara, ... British Journal of Dermatology 177 (5), 1401-1409, 2017 | 386 | 2017 |
Activate: randomized clinical trial of BCG vaccination against infection in the elderly EJ Giamarellos-Bourboulis, M Tsilika, S Moorlag, N Antonakos, A Kotsaki, ... Cell 183 (2), 315-323. e9, 2020 | 339 | 2020 |
Engagement of fatty acids with toll‐like receptor 2 drives interleukin‐1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal–induced gouty arthritis LAB Joosten, MG Netea, E Mylona, MI Koenders, RKS Malireddi, ... Arthritis & Rheumatism 62 (11), 3237-3248, 2010 | 320 | 2010 |
Macrophage activation-like syndrome: a distinct entity leading to early death in sepsis E Karakike, EJ Giamarellos-Bourboulis Frontiers in immunology 10, 428603, 2019 | 317 | 2019 |