Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10269), 99-111, 2021 | 5369 | 2021 |
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker, ... The Lancet 396 (10249), 467-478, 2020 | 2790 | 2020 |
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman, PM Folegatti, ... The Lancet 396 (10267), 1979-1993, 2020 | 1688 | 2020 |
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four … M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10277), 881-891, 2021 | 1346 | 2021 |
A guide to vaccinology: from basic principles to new developments AJ Pollard, EM Bijker Nature Reviews Immunology 21 (2), 83-100, 2021 | 1178 | 2021 |
Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity EM Bijker, GJH Bastiaens, AC Teirlinck, GJ van Gemert, W Graumans, ... Proceedings of the National Academy of Sciences 110 (19), 7862-7867, 2013 | 221 | 2013 |
Controlled human malaria infections by intradermal injection of cryopreserved Plasmodium falciparum sporozoites M Roestenberg, EM Bijker, BKL Sim, PF Billingsley, ER James, ... The American journal of tropical medicine and hygiene 88 (1), 5, 2013 | 175 | 2013 |
Cytotoxic Markers Associate With Protection Against Malaria in Human Volunteers Immunized With Plasmodium falciparum Sporozoites EM Bijker, AC Teirlinck, R Schats, GJ van Gemert, M van de Vegte-Bolmer, ... The Journal of infectious diseases 210 (10), 1605-1615, 2014 | 126 | 2014 |
Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum MC Behet, L Foquet, GJ van Gemert, EM Bijker, P Meuleman, ... Malaria journal 13, 1-12, 2014 | 114 | 2014 |
Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial J Walk, IJ Reuling, MC Behet, L Meerstein-Kessel, W Graumans, ... BMC medicine 15, 1-12, 2017 | 93 | 2017 |
Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria TM Tran, MB Jones, A Ongoiba, EM Bijker, R Schats, P Venepally, ... Scientific reports 6 (1), 31291, 2016 | 84 | 2016 |
BAFF and BAFF receptor levels correlate with B cell subset activation and redistribution in controlled human malaria infection A Scholzen, AC Teirlinck, EM Bijker, M Roestenberg, CC Hermsen, ... The Journal of Immunology 192 (8), 3719-3729, 2014 | 81 | 2014 |
Memory B-Cell and Antibody Responses Induced by Plasmodium falciparum Sporozoite Immunization W Nahrendorf, A Scholzen, EM Bijker, AC Teirlinck, GJH Bastiaens, ... The Journal of infectious diseases 210 (12), 1981-1990, 2014 | 80 | 2014 |
Safety, immunogenicity, and protective efficacy of intradermal immunization with aseptic, purified, cryopreserved Plasmodium falciparum sporozoites in volunteers under … GJH Bastiaens, MPA van Meer, A Scholzen, JM Obiero, ... The American journal of tropical medicine and hygiene 94 (3), 663, 2016 | 70 | 2016 |
Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites R Schats, EM Bijker, GJ van Gemert, W Graumans, ... PloS one 10 (5), e0124243, 2015 | 67 | 2015 |
Novel approaches to whole sporozoite vaccination against malaria EM Bijker, S Borrmann, SH Kappe, B Mordmüller, BK Sack, SM Khan Vaccine 33 (52), 7462-7468, 2015 | 65 | 2015 |
Sporozoite immunization of human volunteers under mefloquine prophylaxis is safe, immunogenic and protective: a double-blind randomized controlled clinical trial EM Bijker, R Schats, JM Obiero, MC Behet, GJ van Gemert, ... PLoS One 9 (11), e112910, 2014 | 62 | 2014 |
Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers MBB McCall, LJ Wammes, MCC Langenberg, GJ Van Gemert, J Walk, ... Science translational medicine 9 (395), eaag2490, 2017 | 48 | 2017 |
Gut mucosal cell damage in meningococcal sepsis in children: Relation with clinical outcome* JPM Derikx, EM Bijker, GD Vos, AA van Bijnen, E Heineman, ... Critical care medicine 38 (1), 133, 2010 | 45 | 2010 |
Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression AC Teirlinck, M Roestenberg, EM Bijker, SL Hoffman, RW Sauerwein, ... Infection and immunity 83 (9), 3732-3739, 2015 | 40 | 2015 |