YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli H Masuda, Q Tan, N Awano, KP Wu, M Inouye Molecular microbiology 84 (5), 979-989, 2012 | 293 | 2012 |
Structural reorganization of α-synuclein at low pH observed by NMR and REMD simulations KP Wu, DS Weinstock, C Narayanan, RM Levy, J Baum Journal of molecular biology 391 (4), 784-796, 2009 | 220 | 2009 |
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes W Zhang, KP Wu, MA Sartori, HB Kamadurai, A Ordureau, C Jiang, ... Molecular cell 62 (1), 121-136, 2016 | 176 | 2016 |
Structural basis of a flavivirus recognized by its neutralizing antibody: solution structure of the domain III of the Japanese encephalitis virus envelope protein KP Wu, CW Wu, YP Tsao, TW Kuo, YC Lou, CW Lin, SC Wu, JW Cheng Journal of Biological Chemistry 278 (46), 46007-46013, 2003 | 172 | 2003 |
Characterization of conformational and dynamic properties of natively unfolded human and mouse α-synuclein ensembles by NMR: implication for aggregation KP Wu, S Kim, DA Fela, J Baum Journal of molecular biology 378 (5), 1104-1115, 2008 | 156 | 2008 |
Dual RING E3 architectures regulate multiubiquitination and ubiquitin chain elongation by APC/C NG Brown, R VanderLinden, ER Watson, F Weissmann, A Ordureau, ... Cell 165 (6), 1440-1453, 2016 | 149 | 2016 |
A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes MPC Mulder, K Witting, I Berlin, JN Pruneda, KP Wu, JG Chang, R Merkx, ... Nature chemical biology 12 (7), 523-530, 2016 | 143 | 2016 |
Detection of transient interchain interactions in the intrinsically disordered protein α-synuclein by NMR paramagnetic relaxation enhancement KP Wu, J Baum Journal of the American Chemical Society 132 (16), 5546-5547, 2010 | 126 | 2010 |
Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans TJ Yang, YC Chang, TP Ko, P Draczkowski, YC Chien, YC Chang, KP Wu, ... Proceedings of the National Academy of Sciences 117 (3), 1438-1446, 2020 | 98 | 2020 |
Simeprevir potently suppresses SARS-CoV-2 replication and synergizes with remdesivir HS Lo, KPY Hui, HM Lai, X He, KS Khan, S Kaur, J Huang, Z Li, ... ACS central science 7 (5), 792-802, 2021 | 84 | 2021 |
Itch WW domains inhibit its E3 ubiquitin ligase activity by blocking E2-E3 ligase trans-thiolation C Riling, H Kamadurai, S Kumar, CE O'Leary, KP Wu, EE Manion, M Ying, ... Journal of Biological Chemistry 290 (39), 23875-23887, 2015 | 72 | 2015 |
Unveiling transient protein-protein interactions that modulate inhibition of alpha-synuclein aggregation by beta-synuclein, a pre-synaptic protein that co-localizes with alpha … MK Janowska, KP Wu, J Baum Scientific reports 5 (1), 15164, 2015 | 67 | 2015 |
Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress NN Fang, M Zhu, A Rose, KP Wu, T Mayor Nature communications 7 (1), 12907, 2016 | 65 | 2016 |
VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism YH Chen, TY Huang, YT Lin, SY Lin, WH Li, HJ Hsiao, RL Yan, HW Tang, ... Nature communications 12 (1), 1322, 2021 | 64 | 2021 |
The A53T mutation is key in defining the differences in the aggregation kinetics of human and mouse α-synuclein L Kang, KP Wu, M Vendruscolo, J Baum Journal of the American Chemical Society 133 (34), 13465-13470, 2011 | 58 | 2011 |
Insights into dynamics of inhibitor and ubiquitin-like protein binding in SARS-CoV-2 papain-like protease YK Bosken, T Cholko, YC Lou, KP Wu, CA Chang Frontiers in molecular biosciences 7, 174, 2020 | 47 | 2020 |
Investigation of the polymeric properties of α-synuclein and comparison with NMR experiments: a replica exchange molecular dynamics study C Narayanan, DS Weinstock, KP Wu, J Baum, RM Levy Journal of chemical theory and computation 8 (10), 3929-3942, 2012 | 40 | 2012 |
Distinguishing among structural ensembles of the GB1 peptide: REMD simulations and NMR experiments DS Weinstock, C Narayanan, AK Felts, M Andrec, RM Levy, KP Wu, ... Journal of the American Chemical Society 129 (16), 4858-4859, 2007 | 31 | 2007 |
Fast hydrogen exchange affects 15N relaxation measurements in intrinsically disordered proteins S Kim, KP Wu, J Baum Journal of biomolecular NMR 55, 249-256, 2013 | 26 | 2013 |
Branched ubiquitination: detection methods, biological functions and chemical synthesis YS Wang, KP Wu, HK Jiang, P Kurkute, RH Chen Molecules 25 (21), 5200, 2020 | 24 | 2020 |