A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN M Rahdar, T Inoue, T Meyer, J Zhang, F Vazquez, PN Devreotes Proceedings of the National Academy of Sciences 106 (2), 480-485, 2009 | 322 | 2009 |
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index W Shen, CL De Hoyos, MT Migawa, TA Vickers, H Sun, A Low, TA Bell III, ... Nature biotechnology 37 (6), 640-650, 2019 | 251 | 2019 |
Synthetic CRISPR RNA-Cas9–guided genome editing in human cells M Rahdar, MA McMahon, TP Prakash, EE Swayze, CF Bennett, ... Proceedings of the National Academy of Sciences 112 (51), E7110-E7117, 2015 | 219 | 2015 |
Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesis J Wen, J Xiao, M Rahdar, BP Choudhury, J Cui, GS Taylor, JD Esko, ... Proceedings of the National Academy of Sciences 111 (44), 15723-15728, 2014 | 122 | 2014 |
A secretory kinase complex regulates extracellular protein phosphorylation J Cui, J Xiao, VS Tagliabracci, J Wen, M Rahdar, JE Dixon elife 4, e06120, 2015 | 121 | 2015 |
Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis D Bolduc, M Rahdar, B Tu-Sekine, SC Sivakumaren, D Raben, LM Amzel, ... Elife 2, e00691, 2013 | 118 | 2013 |
Reading dynamic kinase activity in living cells for high-throughput screening MD Allen, LM DiPilato, M Rahdar, YR Ren, C Chong, JO Liu, J Zhang ACS chemical biology 1 (6), 371-376, 2006 | 117 | 2006 |
Gene editing: not just for translation anymore MA McMahon, M Rahdar, M Porteus Nature methods 9 (1), 28-31, 2012 | 76 | 2012 |
Chemically modified Cpf1-CRISPR RNAs mediate efficient genome editing in mammalian cells MA McMahon, TP Prakash, DW Cleveland, CF Bennett, M Rahdar Molecular Therapy 26 (5), 1228-1240, 2018 | 67 | 2018 |
Live-cell molecular analysis of Akt activation reveals roles for activation loop phosphorylation B Ananthanarayanan, M Fosbrink, M Rahdar, J Zhang Journal of Biological Chemistry 282 (50), 36634-36641, 2007 | 65 | 2007 |
TALENs facilitate single-step seamless SDF correction of F508del CFTR in airway epithelial submucosal gland cell-derived CF-iPSCs S Suzuki, RG Sargent, B Illek, H Fischer, A Esmaeili-Shandiz, MJ Yezzi, ... Molecular Therapy-Nucleic Acids 5, 2016 | 48 | 2016 |
A new class of cancer-associated PTEN mutations defined by membrane translocation defects HN Nguyen, JM Yang Jr, M Rahdar, M Keniry, KF Swaney, R Parsons, ... Oncogene 34 (28), 3737-3743, 2015 | 38 | 2015 |
Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1 TA Vickers, M Rahdar, TP Prakash, ST Crooke Nucleic Acids Research 47 (20), 10865-10880, 2019 | 31 | 2019 |
Modified CRISPR RNA and modified single CRISPR RNA and uses thereof M Rahdar, TP Prakash, EE Swayze, CF Bennett US Patent 11,414,657, 2022 | 9 | 2022 |
GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells MA McMahon, M Rahdar, S Mukhopadhyay, HH Bui, C Hart, S Damle, ... Molecular Therapy-Nucleic Acids 32, 289-301, 2023 | 2 | 2023 |
Gene disruption using chemically modified CRISPR-Cpf1 RNA MA McMahon, M Rahdar CRISPR Guide RNA Design: Methods and Protocols, 49-60, 2021 | 2 | 2021 |
Understanding the nature of PTEN auto-inhibition by its carboxy-terminal tail M Rahdar Dissertation Abstracts International 72 (10), 2011 | 1 | 2011 |
Modified crispr rna and modified single crispr rna and uses thereof M Rahdar, TP Prakash, EE Swayze, CF Bennett US Patent App. 17/850,456, 2023 | | 2023 |
MODIFIED CRISPR RNA AND ITS USES M RAHDAR, TP Prakash, EE Swayze, CF Bennett, MA MCMAHON | | 2020 |
Modified crispr rna and uses thereof M RAHDAR, TP Prakash, EE Swayze, CF Bennett, MA McMahon | | 2018 |