Microglial activation resulting from CD40-CD40L interaction after β-amyloid stimulation J Tan, T Town, D Paris, T Mori, Z Suo, F Crawford, MP Mattson, RA Flavell, ... Science 286 (5448), 2352-2355, 1999 | 472 | 1999 |
Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease NS Patel, D Paris, V Mathura, AN Quadros, FC Crawford, MJ Mullan Journal of neuroinflammation 2, 1-10, 2005 | 381 | 2005 |
Cholesterol Accumulates in Senile plaques of Alzheimer Disease patients and in Transgenic APPsw Mice T Mori, D Paris, T Town, AM Rojiani, DL Sparks, A Delledonne, ... Journal of Neuropathology & Experimental Neurology 60 (8), 778-785, 2001 | 231 | 2001 |
Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease D Paris, NJ Ganey, V Laporte, NS Patel, D Beaulieu-Abdelahad, ... Journal of neuroinflammation 7, 1-15, 2010 | 197 | 2010 |
Inhibition of angiogenesis by Aβ peptides D Paris, K Townsend, A Quadros, J Humphrey, J Sun, S Brem, ... Angiogenesis 7, 75-85, 2004 | 175 | 2004 |
Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier D Paris, C Bachmeier, N Patel, A Quadros, CH Volmar, V Laporte, ... Molecular Medicine 17, 149-162, 2011 | 164 | 2011 |
Impaired angiogenesis in a transgenic mouse model of cerebral amyloidosis D Paris, N Patel, A DelleDonne, A Quadros, R Smeed, M Mullan Neuroscience letters 366 (1), 80-85, 2004 | 158 | 2004 |
α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease D Shea, CC Hsu, TM Bi, N Paranjapye, MC Childers, J Cochran, ... Proceedings of the National Academy of Sciences 116 (18), 8895-8900, 2019 | 154 | 2019 |
Vasoactive effects of Aβ in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation D Paris, J Humphrey, A Quadros, N Patel, R Crescentini, F Crawford, ... Neurological research 25 (6), 642-651, 2003 | 154 | 2003 |
Alzheimer’s β‐amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR‐2 NS Patel, VS Mathura, C Bachmeier, D Beaulieu‐Abdelahad, V Laporte, ... Journal of neurochemistry 112 (1), 66-76, 2010 | 121 | 2010 |
Inhibition of angiogenesis and tumor growth by β and γ-secretase inhibitors D Paris, A Quadros, N Patel, A DelleDonne, J Humphrey, M Mullan European journal of pharmacology 514 (1), 1-15, 2005 | 121 | 2005 |
Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury BC Mouzon, C Bachmeier, JO Ojo, CM Acker, S Ferguson, D Paris, ... Annals of clinical and translational neurology 5 (1), 64-80, 2018 | 118 | 2018 |
Proinflammatory and vasoactive effects of Aβ in the cerebrovasculature KP Townsend, D Obregon, A Quadros, N Patel, CH Volmar, D Paris, ... Annals of the New York Academy of Sciences 977 (1), 65-76, 2002 | 117 | 2002 |
Inhibition of Aβ production by NF-κB inhibitors D Paris, N Patel, A Quadros, M Linan, P Bakshi, G Ait-Ghezala, M Mullan Neuroscience letters 415 (1), 11-16, 2007 | 109 | 2007 |
Inhibition of Alzheimer's β-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism D Paris, T Town, TA Parker, J Tan, J Humphrey, F Crawford, M Mullan Experimental neurology 157 (1), 211-221, 1999 | 108 | 1999 |
Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis J Tan, T Town, D Paris, A Placzek, T Parker, F Crawford, H Yu, ... Journal of neuroimmunology 97 (1-2), 77-85, 1999 | 104 | 1999 |
Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood–brain barrier C Bachmeier, D Beaulieu-Abdelahad, M Mullan, D Paris European journal of pharmacology 659 (2-3), 124-129, 2011 | 102 | 2011 |
Nilvadipine antagonizes both Aβ vasoactivity in isolated arteries, and the reduced cerebral blood flow in APPsw transgenic mice D Paris, A Quadros, J Humphrey, N Patel, R Crescentini, F Crawford, ... Brain research 999 (1), 53-61, 2004 | 92 | 2004 |
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor J Sun, MA Blaskovich, RK Jain, F Delarue, D Paris, S Brem, ... Cancer research 64 (10), 3586-3592, 2004 | 91 | 2004 |
Soluble β-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway D Paris, T Town, T Mori, TA Parker, J Humphrey, M Mullan Neurobiology of aging 21 (2), 183-197, 2000 | 84 | 2000 |