The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling A Bock, N Merten, R Schrage, C Dallanoce, J Bätz, J Klöckner, J Schmitz, ... Nature communications 3 (1), 1044, 2012 | 160 | 2012 |
Total syntheses of anominine and tubingensin A M Bian, Z Wang, X Xiong, Y Sun, C Matera, KC Nicolaou, A Li Journal of the American Chemical Society 134 (19), 8078-8081, 2012 | 118 | 2012 |
Photoswitchable antimetabolite for targeted photoactivated chemotherapy C Matera, AMJ Gomila, N Camarero, M Libergoli, C Soler, P Gorostiza Journal of the American Chemical Society 140 (46), 15764-15773, 2018 | 109 | 2018 |
Involvement of α7 nAChR subtype in rat oxaliplatin-induced neuropathy: effects of selective activation LDC Mannelli, A Pacini, C Matera, M Zanardelli, T Mello, M De Amici, ... Neuropharmacology 79, 37-48, 2014 | 101 | 2014 |
Ligand binding ensembles determine graded agonist efficacies at a G protein-coupled receptor A Bock, M Bermudez, F Krebs, C Matera, B Chirinda, D Sydow, ... Journal of Biological Chemistry 291 (31), 16375-16389, 2016 | 85 | 2016 |
An azobenzene-based single-component supramolecular polymer responsive to multiple stimuli in water E Fuentes, M Gerth, JA Berrocal, C Matera, P Gorostiza, IK Voets, S Pujals, ... Journal of the American Chemical Society 142 (22), 10069-10078, 2020 | 71 | 2020 |
Optical control of cardiac function with a photoswitchable muscarinic agonist F Riefolo, C Matera, A Garrido-Charles, AMJ Gomila, R Sortino, L Agnetta, ... Journal of the American Chemical Society 141 (18), 7628-7636, 2019 | 63 | 2019 |
Pharmacological approaches to targeting muscarinic acetylcholine receptors C Matera, A M Tata Recent Patents on CNS Drug Discovery (Discontinued) 9 (2), 85-100, 2014 | 44 | 2014 |
Fluorination of photoswitchable muscarinic agonists tunes receptor pharmacology and photochromic properties L Agnetta, M Bermudez, F Riefolo, C Matera, E Claro, R Messerer, ... Journal of Medicinal Chemistry 62 (6), 3009-3020, 2019 | 43 | 2019 |
Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl‐Δ2‐Isoxazoline Derivatives as Potent and Selective Agonists of α7 … C Dallanoce, P Magrone, C Matera, F Frigerio, G Grazioso, M De Amici, ... ChemMedChem 6 (5), 889-903, 2011 | 41 | 2011 |
Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes L Rizzi, C Dallanoce, C Matera, P Magrone, L Pucci, C Gotti, F Clementi, ... Bioorganic & medicinal chemistry letters 18 (16), 4651-4654, 2008 | 40 | 2008 |
Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity C Matera, L Flammini, M Quadri, V Vivo, V Ballabeni, U Holzgrabe, ... European journal of medicinal chemistry 75, 222-232, 2014 | 39 | 2014 |
Adrenergic modulation with photochromic ligands D Prischich, AMJ Gomila, S Milla‐Navarro, G Sangüesa, R Diez‐Alarcia, ... Angewandte Chemie International Edition 60 (7), 3625-3631, 2021 | 35 | 2021 |
Design of novel α7-subtype-preferring nicotinic acetylcholine receptor agonists: Application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies G Grazioso, DY Pomè, C Matera, F Frigerio, L Pucci, C Gotti, C Dallanoce, ... Bioorganic & medicinal chemistry letters 19 (22), 6353-6357, 2009 | 33 | 2009 |
Donor–Acceptor Stenhouse Adduct Displaying Reversible Photoswitching in Water and Neuronal Activity R Castagna, G Maleeva, D Pirovano, C Matera, P Gorostiza Journal of the American Chemical Society 144 (34), 15595-15602, 2022 | 23 | 2022 |
Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells I Cristofaro, Z Spinello, C Matera, M Fiore, L Conti, M De Amici, ... Neurochemistry International 118, 52-60, 2018 | 22 | 2018 |
Novel tricyclic Δ2-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: Synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes C Dallanoce, F Frigerio, G Martelli, G Grazioso, C Matera, DY Pomè, ... Bioorganic & medicinal chemistry 18 (12), 4498-4508, 2010 | 22 | 2010 |
Ligand-specific allosteric coupling controls G-protein-coupled receptor signaling J Holze, M Bermudez, EM Pfeil, M Kauk, T Bödefeld, M Irmen, C Matera, ... ACS pharmacology & translational science 3 (5), 859-867, 2020 | 21 | 2020 |
On the selection of an opioid for local skin analgesia: structure-skin permeability relationships UM Musazzi, C Matera, C Dallanoce, F Vacondio, M De Amici, G Vistoli, ... International Journal of Pharmaceutics 489 (1-2), 177-185, 2015 | 21 | 2015 |
Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ2‐Isoxazoline Scaffold: Synthesis and … M Quadri, C Matera, A Silnović, MC Pismataro, NA Horenstein, C Stokes, ... ChemMedChem 12 (16), 1335-1348, 2017 | 20 | 2017 |