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Brian E. McIntosh
Brian E. McIntosh
Global Preclinical Cell & Gene Therapy Lead; Director of Science Experts, Labcorp (formerly Covance)
在 covance.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Mammalian Per-Arnt-Sim proteins in environmental adaptation
BE McIntosh, JB Hogenesch, CA Bradfield
Annual review of physiology 72 (1), 625-645, 2010
4252010
Cloning and characterization of a novel human histone deacetylase, HDAC8
JJ Buggy, ML SIDERIS, P MAK, DD LORIMER, B MCINTOSH, JM CLARK
Biochemical Journal 350 (1), 199-205, 2000
2852000
Nonirradiated NOD, B6. SCID Il2rγ−/− KitW41/W41 (NBSGW) mice support multilineage engraftment of human hematopoietic cells
BE McIntosh, ME Brown, BM Duffin, JP Maufort, DT Vereide, II Slukvin, ...
Stem cell reports 4 (2), 171-180, 2015
2312015
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy
SE Howden, A Gore, Z Li, HL Fung, BS Nisler, J Nie, G Chen, ...
Proceedings of the National Academy of Sciences 108 (16), 6537-6542, 2011
1822011
EBSeq-HMM: a Bayesian approach for identifying gene-expression changes in ordered RNA-seq experiments
N Leng, Y Li, BE McIntosh, BK Nguyen, B Duffin, S Tian, JA Thomson, ...
Bioinformatics 31 (16), 2614-2622, 2015
1072015
Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase
BP Johnson, JA Walisser, Y Liu, AL Shen, EL McDearmon, SM Moran, ...
Proceedings of the National Academy of Sciences 111 (52), 18757-18762, 2014
922014
Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents
S Meyer, JP Maufort, J Nie, R Stewart, BE McIntosh, LR Conti, KM Ahmad, ...
PLoS One 8 (8), e71798, 2013
652013
Species-specific developmental timing is maintained by pluripotent stem cells ex utero
C Barry, MT Schmitz, P Jiang, MP Schwartz, BM Duffin, S Swanson, ...
Developmental biology 423 (2), 101-110, 2017
562017
A humanized mouse model generated using surplus neonatal tissue
ME Brown, Y Zhou, BE McIntosh, IG Norman, HE Lou, M Biermann, ...
Stem Cell Reports 10 (4), 1175-1183, 2018
542018
Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques
C Barry, MT Schmitz, NE Propson, Z Hou, J Zhang, BK Nguyen, JM Bolin, ...
Experimental Biology and Medicine 242 (17), 1679-1689, 2017
412017
Discovery of survival factor for primitive chronic myeloid leukemia cells using induced pluripotent stem cells
K Suknuntha, Y Ishii, L Tao, K Hu, BE McIntosh, D Yang, S Swanson, ...
Stem cell research 15 (3), 678-693, 2015
382015
An expandable, inducible hemangioblast state regulated by fibroblast growth factor
DT Vereide, V Vickerman, SA Swanson, LF Chu, BE McIntosh, ...
Stem cell reports 3 (6), 1043-1057, 2014
302014
A human pluripotent stem cell-based screen for smooth muscle cell differentiation and maturation identifies inhibitors of intimal hyperplasia
J Zhang, BE McIntosh, B Wang, ME Brown, MD Probasco, S Webster, ...
Stem cell reports 12 (6), 1269-1281, 2019
262019
Inferring regulatory programs governing region specificity of neuroepithelial stem cells during early hindbrain and spinal cord development
D Chasman, N Iyer, AF Siahpirani, ME Silva, E Lippmann, B McIntosh, ...
Cell systems 9 (2), 167-186. e12, 2019
222019
No irradiation required: The future of humanized immune system modeling in murine hosts
BE McIntosh, ME Brown
Chimerism 6 (1-2), 40-45, 2015
202015
Adeno-associated virus (AAV)-based gene therapy products: What are toxicity studies in non-human primates showing us?
P Baldrick, B McIntosh, M Prasad
Regulatory Toxicology and Pharmacology 138 (105332), 2023
192023
Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics
C Barry, MT Schmitz, C Argus, JM Bolin, MD Probasco, N Leng, BM Duffin, ...
PLOS Computational Biology 15 (12), e1007543, 2019
142019
Rapid changes in chromatin structure during dedifferentiation of primary hepatocytes in vitro
M Seirup, S Sengupta, S Swanson, BE McIntosh, M Collins, LF Chu, ...
Genomics 114 (3), 110330, 2022
72022
Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques
A Kistner, JA Chichester, L Wang, R Calcedo, JA Greig, LN Cardwell, ...
Gene Therapy 31 (3), 128-143, 2024
12024
Lineage reprogramming of mouse fibroblasts to induced cardiac progenitor cells by defined factors
PA Lalit, M Lea, SA Jackson, BE McIntosh, M Kyba, JA Thomson, ...
Circulation 128 (suppl_22), A19007-A19007, 2013
12013
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