HIV-1 maturation: lessons learned from inhibitors AB Kleinpeter, EO Freed Viruses 12 (9), 940, 2020 | 102 | 2020 |
Cellular IP6 levels limit HIV production while viruses that cannot efficiently package IP6 are attenuated for infection and replication DL Mallery, KMR Faysal, A Kleinpeter, MSC Wilson, M Vaysburd, ... Cell Reports 29 (12), 3983-3996. e4, 2019 | 84 | 2019 |
Structural basis for a novel interaction between the NS1 protein derived from the 1918 influenza virus and RIG-I AS Jureka, AB Kleinpeter, G Cornilescu, CC Cornilescu, CM Petit Structure 23 (11), 2001-2010, 2015 | 61 | 2015 |
A stable immature lattice packages IP6 for HIV capsid maturation DL Mallery, AB Kleinpeter, N Renner, KMR Faysal, M Novikova, L Kiss, ... Science advances 7 (11), eabe4716, 2021 | 57 | 2021 |
The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I AS Jureka, AB Kleinpeter, JL Tipper, KS Harrod, CM Petit Journal of Biological Chemistry 295 (4), 1153-1164, 2020 | 53 | 2020 |
CryoET structures of immature HIV Gag reveal six-helix bundle L Mendonça, D Sun, J Ning, J Liu, A Kotecha, M Olek, T Frosio, X Fu, ... Communications biology 4 (1), 481, 2021 | 38 | 2021 |
HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly N Renner, A Kleinpeter, DL Mallery, A Albecka, KM Rifat Faysal, ... Nature structural & molecular biology 30 (3), 370-382, 2023 | 33 | 2023 |
Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds AB Kleinpeter, AS Jureka, SM Falahat, TJ Green, CM Petit Journal of Biological Chemistry 293 (38), 14659-14668, 2018 | 30 | 2018 |
Enhanced transmissibility and decreased virulence of HIV-1 CRF07_BC may explain its rapid expansion in China Z Cheng, H Yan, Q Li, SD Ablan, A Kleinpeter, EO Freed, H Wu, ... Microbiology Spectrum 10 (4), e00146-22, 2022 | 20 | 2022 |
Structural basis of HIV-1 maturation inhibitor binding and activity S Sarkar, KK Zadrozny, R Zadorozhnyi, RW Russell, CM Quinn, ... Nature Communications 14 (1), 1237, 2023 | 17 | 2023 |
The effect of inositol hexakisphosphate on HIV-1 particle production and infectivity can be modulated by mutations that affect the stability of the immature Gag lattice AB Kleinpeter, Y Zhu, DL Mallery, SD Ablan, L Chen, N Hardenbrook, ... Journal of Molecular Biology 435 (11), 168037, 2023 | 6 | 2023 |
Cellular IP6 levels limit HIV production while viruses that cannot efficiently® package IP6 are attenuated for infection and replication. Cell Rep 29: 3983–3996 DL Mallery, KMR Faysal, A Kleinpeter, MSC Wilson, M Vaysburd, ... | 6 | 2019 |
Structural investigations of interactions between the influenza a virus NS1 and host cellular proteins ME Blake, AB Kleinpeter, AS Jureka, CM Petit Viruses 15 (10), 2063, 2023 | 3 | 2023 |
HIV-1 adapts to lost IP6 coordination through second-site mutations that restore conical capsid assembly A Kleinpeter, DL Mallery, N Renner, A Albecka, JO Klarhof, EO Freed, ... Nature Communications 15 (1), 8017, 2024 | 1 | 2024 |
How to package the RNA of HIV-1 A Kleinpeter, EO Freed Elife 9, e63585, 2020 | 1 | 2020 |
Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir L Briganti, AS Annamalai, SM Bester, G Wei, JR Andino-Moncada, ... bioRxiv, 2024.11. 25.625199, 2024 | | 2024 |
Structural And Functional Insights Into The Influenza A Virus Non-Structural Protein 1 Effector Domain AB Kleinpeter The University of Alabama at Birmingham, 2019 | | 2019 |