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Alex Kleinpeter
Alex Kleinpeter
Postdoctoral Fellow, National Institutes of Helath
在 nih.gov 的电子邮件经过验证
标题
引用次数
引用次数
年份
HIV-1 maturation: lessons learned from inhibitors
AB Kleinpeter, EO Freed
Viruses 12 (9), 940, 2020
1022020
Cellular IP6 levels limit HIV production while viruses that cannot efficiently package IP6 are attenuated for infection and replication
DL Mallery, KMR Faysal, A Kleinpeter, MSC Wilson, M Vaysburd, ...
Cell Reports 29 (12), 3983-3996. e4, 2019
842019
Structural basis for a novel interaction between the NS1 protein derived from the 1918 influenza virus and RIG-I
AS Jureka, AB Kleinpeter, G Cornilescu, CC Cornilescu, CM Petit
Structure 23 (11), 2001-2010, 2015
612015
A stable immature lattice packages IP6 for HIV capsid maturation
DL Mallery, AB Kleinpeter, N Renner, KMR Faysal, M Novikova, L Kiss, ...
Science advances 7 (11), eabe4716, 2021
572021
The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I
AS Jureka, AB Kleinpeter, JL Tipper, KS Harrod, CM Petit
Journal of Biological Chemistry 295 (4), 1153-1164, 2020
532020
CryoET structures of immature HIV Gag reveal six-helix bundle
L Mendonça, D Sun, J Ning, J Liu, A Kotecha, M Olek, T Frosio, X Fu, ...
Communications biology 4 (1), 481, 2021
382021
HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly
N Renner, A Kleinpeter, DL Mallery, A Albecka, KM Rifat Faysal, ...
Nature structural & molecular biology 30 (3), 370-382, 2023
332023
Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds
AB Kleinpeter, AS Jureka, SM Falahat, TJ Green, CM Petit
Journal of Biological Chemistry 293 (38), 14659-14668, 2018
302018
Enhanced transmissibility and decreased virulence of HIV-1 CRF07_BC may explain its rapid expansion in China
Z Cheng, H Yan, Q Li, SD Ablan, A Kleinpeter, EO Freed, H Wu, ...
Microbiology Spectrum 10 (4), e00146-22, 2022
202022
Structural basis of HIV-1 maturation inhibitor binding and activity
S Sarkar, KK Zadrozny, R Zadorozhnyi, RW Russell, CM Quinn, ...
Nature Communications 14 (1), 1237, 2023
172023
The effect of inositol hexakisphosphate on HIV-1 particle production and infectivity can be modulated by mutations that affect the stability of the immature Gag lattice
AB Kleinpeter, Y Zhu, DL Mallery, SD Ablan, L Chen, N Hardenbrook, ...
Journal of Molecular Biology 435 (11), 168037, 2023
62023
Cellular IP6 levels limit HIV production while viruses that cannot efficiently® package IP6 are attenuated for infection and replication. Cell Rep 29: 3983–3996
DL Mallery, KMR Faysal, A Kleinpeter, MSC Wilson, M Vaysburd, ...
62019
Structural investigations of interactions between the influenza a virus NS1 and host cellular proteins
ME Blake, AB Kleinpeter, AS Jureka, CM Petit
Viruses 15 (10), 2063, 2023
32023
HIV-1 adapts to lost IP6 coordination through second-site mutations that restore conical capsid assembly
A Kleinpeter, DL Mallery, N Renner, A Albecka, JO Klarhof, EO Freed, ...
Nature Communications 15 (1), 8017, 2024
12024
How to package the RNA of HIV-1
A Kleinpeter, EO Freed
Elife 9, e63585, 2020
12020
Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir
L Briganti, AS Annamalai, SM Bester, G Wei, JR Andino-Moncada, ...
bioRxiv, 2024.11. 25.625199, 2024
2024
Structural And Functional Insights Into The Influenza A Virus Non-Structural Protein 1 Effector Domain
AB Kleinpeter
The University of Alabama at Birmingham, 2019
2019
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