Mitochondrial dynamics controls T cell fate through metabolic programming MD Buck, D O’Sullivan, RIK Geltink, JD Curtis, CH Chang, DE Sanin, ... Cell 166 (1), 63-76, 2016 | 1265 | 2016 |
Unraveling the complex interplay between T cell metabolism and function RI Klein Geltink, RL Kyle, EL Pearce Annual review of immunology 36 (1), 461-488, 2018 | 686 | 2018 |
Mitochondrial priming by CD28 RIK Geltink, D O’Sullivan, M Corrado, A Bremser, MD Buck, JM Buescher, ... Cell 171 (2), 385-397. e11, 2017 | 285 | 2017 |
Polyamines and eIF5A hypusination modulate mitochondrial respiration and macrophage activation DJ Puleston, MD Buck, RIK Geltink, RL Kyle, G Caputa, D O’Sullivan, ... Cell metabolism 30 (2), 352-363. e8, 2019 | 279 | 2019 |
Acetate promotes T cell effector function during glucose restriction J Qiu, M Villa, DE Sanin, MD Buck, D O’Sullivan, R Ching, M Matsushita, ... Cell reports 27 (7), 2063-2074. e5, 2019 | 256 | 2019 |
Triacylglycerol synthesis enhances macrophage inflammatory function A Castoldi, LB Monteiro, N van Teijlingen Bakker, DE Sanin, N Rana, ... Nature communications 11 (1), 4107, 2020 | 161 | 2020 |
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy RI Klein Geltink, J Edwards-Hicks, P Apostolova, D O’Sullivan, DE Sanin, ... Nature metabolism 2 (8), 703-716, 2020 | 110 | 2020 |
MN1 overexpression is an important step in the development of inv (16) AML C Carella, J Bonten, S Sirma, TA Kranenburg, S Terranova, ... Leukemia 21 (8), 1679-1690, 2007 | 101 | 2007 |
Mitochondrial membrane potential regulates nuclear gene expression in macrophages exposed to prostaglandin E2 DE Sanin, M Matsushita, RIK Geltink, KM Grzes, N van Teijlingen Bakker, ... Immunity 49 (6), 1021-1033. e6, 2018 | 98 | 2018 |
ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer FC Harwood, RI Klein Geltink, BP O’Hara, M Cardone, L Janke, ... Science advances 4 (9), eaar3938, 2018 | 96 | 2018 |
Transsulfuration, minor player or crucial for cysteine homeostasis in cancer HF Zhang, RIK Geltink, SJ Parker, PH Sorensen Trends in cell biology 32 (9), 800-814, 2022 | 73 | 2022 |
Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ... Cancer discovery 11 (11), 2884-2903, 2021 | 60 | 2021 |
Dynamic cardiolipin synthesis is required for CD8+ T cell immunity M Corrado, J Edwards-Hicks, M Villa, LJ Flachsmann, DE Sanin, ... Cell metabolism 32 (6), 981-995. e7, 2020 | 47 | 2020 |
Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes MWJ Schreurs, MAJA Hermsen, RIK Geltink, KBJ Scholten, AATP Brink, ... Blood 106 (8), 2663-2670, 2005 | 45 | 2005 |
The importance of methionine metabolism RI Klein Geltink, EL Pearce Elife 8, e47221, 2019 | 44 | 2019 |
Fever supports CD8+ effector T cell responses by promoting mitochondrial translation D O’Sullivan, MA Stanczak, M Villa, FM Uhl, M Corrado, RI Klein Geltink, ... Proceedings of the National Academy of Sciences 118 (25), e2023752118, 2021 | 38 | 2021 |
Caught in the cROSsfire: GSH controls T cell metabolic reprogramming RIK Geltink, D O’Sullivan, EL Pearce Immunity 46 (4), 525-527, 2017 | 31 | 2017 |
EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism S Ramamoorthy, K Kometani, JS Herman, M Bayer, S Boller, ... Genes & Development 34 (21-22), 1503-1519, 2020 | 27 | 2020 |
A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways I Piragyte, T Clapes, A Polyzou, RI Klein Geltink, S Lefkopoulos, N Yin, ... Nature communications 9 (1), 3090, 2018 | 27 | 2018 |
Zebrafish etv7 regulates red blood cell development through the cholesterol synthesis pathway AM Quintana, F Picchione, RI Klein Geltink, MR Taylor, GC Grosveld Disease models & mechanisms 7 (2), 265-270, 2014 | 25 | 2014 |