Foxp3 reprograms T cell metabolism to function in low-glucose, high-lactate environments A Angelin, L Gil-de-Gómez, S Dahiya, J Jiao, L Guo, MH Levine, Z Wang, ... Cell metabolism 25 (6), 1282-1293. e7, 2017 | 934 | 2017 |
Helios expression is a marker of T cell activation and proliferation T Akimova, UH Beier, L Wang, MH Levine, WW Hancock PloS one 6 (8), e24226, 2011 | 488 | 2011 |
Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3+ T-regulatory cells EF de Zoeten, L Wang, K Butler, UH Beier, T Akimova, H Sai, JE Bradner, ... Molecular and cellular biology, 2011 | 283 | 2011 |
Essential role of mitochondrial energy metabolism in Foxp3+ T-regulatory cell function and allograft survival UH Beier, A Angelin, T Akimova, L Wang, Y Liu, H Xiao, MA Koike, ... The FASEB journal 29 (6), 2315, 2015 | 254 | 2015 |
Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity Y Liu, L Wang, J Predina, R Han, UH Beier, LCS Wang, V Kapoor, ... Nature medicine 19 (9), 1173-1177, 2013 | 232 | 2013 |
Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function and Prolongs Allograft Survival UH Beier, L Wang, TR Bhatti, Y Liu, R Han, G Ge, WW Hancock Molecular and cellular biology 31 (5), 1022-1029, 2011 | 221 | 2011 |
Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms UH Beier, L Wang, R Han, T Akimova, Y Liu, WW Hancock Science signaling 5 (229), ra45-ra45, 2012 | 216 | 2012 |
Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer S Singhal, J Stadanlick, MJ Annunziata, AS Rao, PS Bhojnagarwala, ... Science translational medicine 11 (479), eaat1500, 2019 | 209 | 2019 |
Lactate limits T cell proliferation via the NAD (H) redox state WJ Quinn, J Jiao, T TeSlaa, J Stadanlick, Z Wang, L Wang, T Akimova, ... Cell reports 33 (11), 2020 | 186 | 2020 |
Histone/protein deacetylases and T-cell immune responses T Akimova, UH Beier, Y Liu, L Wang, WW Hancock Blood, The Journal of the American Society of Hematology 119 (11), 2443-2451, 2012 | 150 | 2012 |
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ... Nature chemical biology 16 (7), 731-739, 2020 | 127 | 2020 |
Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells UH Beier, T Akimova, Y Liu, L Wang, WW Hancock Current opinion in immunology 23 (5), 670-678, 2011 | 115 | 2011 |
Ubiquitin-specific protease-7 inhibition impairs Tip60-dependent Foxp3+ T-regulatory cell function and promotes antitumor immunity L Wang, S Kumar, S Dahiya, F Wang, J Wu, K Newick, R Han, A Samanta, ... EBioMedicine 13, 99-112, 2016 | 112 | 2016 |
Mbd2 promotes foxp3 demethylation and T-regulatory-cell function L Wang, Y Liu, R Han, UH Beier, RM Thomas, AD Wells, WW Hancock Molecular and cellular biology 33 (20), 4106-4115, 2013 | 109 | 2013 |
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3 L Wang, Y Liu, R Han, UH Beier, TR Bhatti, T Akimova, MI Greene, ... The Journal of clinical investigation 125 (3), 1111-1123, 2015 | 108 | 2015 |
Metalloproteinases and their inhibitors: influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas T Görögh, UH Beier, J Bäumken, JE Meyer, M Hoffmann, S Gottschlich, ... Head & Neck: Journal for the Sciences and Specialties of the Head and Neck …, 2006 | 98 | 2006 |
Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-Regulatory Cell Development and Function Y Liu, L Wang, R Han, UH Beier, T Akimova, T Bhatti, H Xiao, PA Cole, ... Molecular and cellular biology 34 (21), 3993-4007, 2014 | 90 | 2014 |
HDAC inhibitor therapy in autoimmunity and transplantation WW Hancock, T Akimova, UH Beier, Y Liu, L Wang Annals of the rheumatic diseases 71 (Suppl 2), i46-i54, 2012 | 90 | 2012 |
Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity L Wang, Y Liu, UH Beier, R Han, TR Bhatti, T Akimova, WW Hancock Blood, The Journal of the American Society of Hematology 121 (18), 3631-3639, 2013 | 87 | 2013 |
Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function J Huang, L Wang, S Dahiya, UH Beier, R Han, A Samanta, J Bergman, ... Scientific reports 7 (1), 8626, 2017 | 80 | 2017 |