Designing chemically modified oligonucleotides for targeted gene silencing GF Deleavey, MJ Damha Chemistry & biology 19 (8), 937-954, 2012 | 709 | 2012 |
Chemically modified siRNA: tools and applications JK Watts, GF Deleavey, MJ Damha Drug discovery today 13 (19-20), 842-855, 2008 | 553 | 2008 |
i-Motif DNA: structural features and significance to cell biology H Abou Assi, M Garavís, C González, MJ Damha Nucleic acids research 46 (16), 8038-8056, 2018 | 346 | 2018 |
Fiber-optic DNA sensor for fluorometric nucleic acid determination PAE Piunno, UJ Krull, RHE Hudson, MJ Damha, H Cohen Analytical chemistry 67 (15), 2635-2643, 1995 | 325 | 1995 |
Hybrids of RNA and arabinonucleic acids (ANA and 2 ‘F-ANA) are substrates of ribonuclease H MJ Damha, CJ Wilds, A Noronha, I Brukner, G Borkow, D Arion, ... Journal of the American Chemical Society 120 (49), 12976-12977, 1998 | 266 | 1998 |
Improvements in siRNA properties mediated by 2′-deoxy-2′-fluoro-β- d -arabinonucleic acid (FANA) T Dowler, D Bergeron, AL Tedeschi, L Paquet, N Ferrari, MJ Damha Nucleic acids research 34 (6), 1669-1675, 2006 | 242 | 2006 |
An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis MJ Damha, PA Giannaris, SV Zabarylo Nucleic Acids Research 18 (13), 3813-3821, 1990 | 242 | 1990 |
2′-Deoxy-2′-fluoro-β-D-arabinonucleosides and oligonucleotides (2′ F-ANA): synthesis and physicochemical studies CJ Wilds, MJ Damha Nucleic acids research 28 (18), 3625-3635, 2000 | 229 | 2000 |
Fiber optic biosensor for fluorimetric detection of DNA hybridization PAE Piunno, UJ Krull, RHE Hudson, MJ Damha, H Cohen Analytica Chimica Acta 288 (3), 205-214, 1994 | 222 | 1994 |
Nucleic acid dendrimers: novel biopolymer structures RHE Hudson, MJ Damha Journal of the American Chemical Society 115 (6), 2119-2124, 1993 | 192 | 1993 |
Recent progress in non-native nucleic acid modifications LK McKenzie, R El-Khoury, JD Thorpe, MJ Damha, M Hollenstein Chemical Society Reviews 50 (8), 5126-5164, 2021 | 187 | 2021 |
Oligoribonucleotide synthesis: the silyl-phosphoramidite method MJ Damha, KK Ogilvie Protocols for oligonucleotides and analogs: Synthesis and properties, 81-114, 1993 | 170 | 1993 |
Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat KT Gagnon, HM Pendergraff, GF Deleavey, EE Swayze, P Potier, ... Biochemistry 49 (47), 10166-10178, 2010 | 167 | 2010 |
G-quadruplex induced stabilization by 2′-deoxy-2′-fluoro-d-arabinonucleic acids (2′F-ANA) CG Peng, MJ Damha Nucleic acids research 35 (15), 4977-4988, 2007 | 162 | 2007 |
Synthesis and Biophysical Properties of Arabinonucleic Acids (ANA): Circular Dichroic Spectra, Melting Temperatures, and Ribonuclease H Susceptibility of ANA⊙ RNA Hybrid Duplexes AM Noronha, CJ Wilds, CN Lok, K Viazovkina, D Arion, MA Parniak, ... Biochemistry 39 (24), 7050-7062, 2000 | 138 | 2000 |
2′-Deoxy-2′-fluoro-β- d -arabinonucleic acid (2′F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing A Kalota, L Karabon, CR Swider, E Viazovkina, M Elzagheid, MJ Damha, ... Nucleic acids research 34 (2), 451-461, 2006 | 134 | 2006 |
Oligoribonucleotides containing 2′, 5′-phosphodiester linkages exhibit binding selectivity for 3′, 5′-RNA over 3′, 5′-ssDNA PA Giannaris, MJ Damha Nucleic acids research 21 (20), 4742-4749, 1993 | 129 | 1993 |
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing GF Deleavey, JK Watts, T Alain, F Robert, A Kalota, V Aishwarya, ... Nucleic acids research 38 (13), 4547-4557, 2010 | 122 | 2010 |
Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations YM Abbas, BT Laudenbach, S Martínez-Montero, R Cencic, M Habjan, ... Proceedings of the National Academy of Sciences 114 (11), E2106-E2115, 2017 | 118 | 2017 |
Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2 ‘F-ANA constructs containing acyclic nucleotide inserts MM Mangos, KL Min, E Viazovkina, A Galarneau, MI Elzagheid, ... Journal of the American Chemical Society 125 (3), 654-661, 2003 | 112 | 2003 |