Aire-expressing ILC3-like cells in the lymph node display potent APC features T Yamano, J Dobeš, M Vobořil, M Steinert, T Brabec, N Ziętara, ... Journal of Experimental Medicine 216 (5), 1027-1037, 2019 | 63 | 2019 |
Gastrointestinal autoimmunity associated with loss of central tolerance to enteric α-defensins J Dobeš, A Neuwirth, M Dobešová, M Vobořil, J Balounová, O Ballek, ... Gastroenterology 149 (1), 139-150, 2015 | 40 | 2015 |
Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation M Vobořil, T Brabec, J Dobeš, I Šplíchalová, J Březina, A Čepková, ... Nature Communications 11 (1), 2361, 2020 | 39 | 2020 |
Extrathymic expression of Aire controls the induction of effective TH17 cell-mediated immune response to Candida albicans J Dobeš, O Ben-Nun, A Binyamin, L Stoler-Barak, BE Oftedal, Y Goldfarb, ... Nature immunology 23 (7), 1098-1108, 2022 | 38 | 2022 |
HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage–Associated Tumorigenesis L Janeckova, V Pospichalova, B Fafilek, M Vojtechova, J Tureckova, ... Molecular Cancer Research 13 (7), 1139-1148, 2015 | 35 | 2015 |
IL18 signaling promotes homing of mature Tregs into the thymus C Peligero-Cruz, T Givony, A Sebe-Pedros, J Dobeš, N Kadouri, S Nevo, ... Elife 9, e58213, 2020 | 30 | 2020 |
NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling J Stancikova, M Krausova, M Kolar, B Fafilek, J Svec, R Sedlacek, ... Cellular signalling 27 (2), 245-256, 2015 | 30 | 2015 |
Eosinophils from patients with type 1 diabetes mellitus express high level of myeloid alpha-defensins and myeloperoxidase A Neuwirth, J Dobeš, J Oujezdská, O Ballek, M Benešová, Z Šumník, ... Cellular immunology 273 (2), 158-163, 2012 | 30 | 2012 |
Thymic mimetic cells function beyond self-tolerance T Givony, D Leshkowitz, D Del Castillo, S Nevo, N Kadouri, B Dassa, ... Nature 622 (7981), 164-172, 2023 | 23 | 2023 |
The emerging family of RORγt+ antigen-presenting cells J Abramson, J Dobeš, M Lyu, GF Sonnenberg Nature Reviews Immunology 24 (1), 64-77, 2024 | 21 | 2024 |
Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation Y Goldfarb, T Givony, N Kadouri, J Dobeš, C Peligero-Cruz, I Zalayat, ... Journal of Experimental Medicine 218 (11), e20201076, 2021 | 19 | 2021 |
Enteric α-defensins on the verge of intestinal immune tolerance and inflammation D Filipp, T Brabec, M Vobořil, J Dobeš Seminars in cell & developmental biology 88, 138-146, 2019 | 19 | 2019 |
A novel conditional Aire allele enables cell‐specific ablation of the immune tolerance regulator Aire J Dobeš, F Edenhofer, M Vobořil, T Brabec, M Dobešová, A Čepková, ... European journal of immunology 48 (3), 546-548, 2018 | 11 | 2018 |
A model of preferential pairing between epithelial and dendritic cells in thymic antigen transfer M Vobořil, J Březina, T Brabec, J Dobeš, O Ballek, M Dobešová, ... Elife 11, e71578, 2022 | 10 | 2022 |
Transcriptional regulation of the thymus master regulator Foxn1 N Kadouri, T Givony, S Nevo, J Hey, S Ben Dor, G Damari, B Dassa, ... Science Immunology 7 (74), eabn8144, 2022 | 8 | 2022 |
IL-17-driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum T Brabec, M Vobořil, D Schierová, E Valter, I Šplíchalová, J Dobeš, ... Mucosal Immunology 16 (4), 373-385, 2023 | 7 | 2023 |
Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover T Brabec, M Schwarzer, K Kováčová, M Dobešová, D Schierová, ... Journal of Experimental Medicine 221 (1), e20230194, 2023 | 6 | 2023 |
Epithelial antigen presentation controls commensal-specific intraepithelial T-cells in the gut T Brabec, M Schwarzer, K Kováčová, M Dobešová, D Schierová, ... bioRxiv, 2022.08. 21.504672, 2022 | 5 | 2022 |
Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse V Kriz, M Krausova, P Buresova, J Dobes, D Hrckulak, O Babosova, ... Transgenic Research 26, 689-701, 2017 | 4 | 2017 |
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease Y Gruper, ASB Wolff, L Glanz, F Spoutil, MC Marthinussen, A Osickova, ... Nature 624 (7992), 653-662, 2023 | 3 | 2023 |