Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei TN Siegel, DR Hekstra, LE Kemp, LM Figueiredo, JE Lowell, D Fenyo, ... Genes & development 23 (9), 1063-1076, 2009 | 427 | 2009 |
Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites TN Siegel, DR Hekstra, X Wang, S Dewell, GAM Cross Nucleic acids research 38 (15), 4946-4957, 2010 | 363 | 2010 |
Evolvability as a function of purifying selection in TEM-1 β-lactamase MA Stiffler, DR Hekstra, R Ranganathan Cell 160 (5), 882-892, 2015 | 330 | 2015 |
Polymeric peptide pigments with sequence-encoded properties A Lampel, SA McPhee, HA Park, GG Scott, S Humagain, DR Hekstra, ... Science 356 (6342), 1064-1068, 2017 | 287 | 2017 |
Absolute mRNA concentrations from sequence‐specific calibration of oligonucleotide arrays D Hekstra, AR Taussig, M Magnasco, F Naef Nucleic acids research 31 (7), 1962-1968, 2003 | 219 | 2003 |
Electric-field-stimulated protein mechanics DR Hekstra, KI White, MA Socolich, RW Henning, V Šrajer, ... Nature 540 (7633), 400-405, 2016 | 212 | 2016 |
Contingency and statistical laws in replicate microbial closed ecosystems DR Hekstra, S Leibler Cell 149 (5), 1164-1173, 2012 | 117 | 2012 |
Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging TN Siegel, DR Hekstra, GAM Cross Molecular and biochemical parasitology 160 (2), 171-174, 2008 | 98 | 2008 |
Microbial population dynamics by digital in-line holographic microscopy Z Frentz, S Kuehn, D Hekstra, S Leibler Review of Scientific Instruments 81 (8), 2010 | 42 | 2010 |
A unifying Bayesian framework for merging X-ray diffraction data KM Dalton, JB Greisman, DR Hekstra Nature Communications 13 (1), 7764, 2022 | 27 | 2022 |
reciprocalspaceship: a Python library for crystallographic data analysis JB Greisman, KM Dalton, DR Hekstra Journal of Applied Crystallography 54 (5), 1521-1529, 2021 | 24 | 2021 |
Holographic microscope S Leibler, S Kuehn, Z Frentz, D Hekstra US Patent 8,049,814, 2011 | 18 | 2011 |
Emerging time-resolved x-ray diffraction approaches for protein dynamics DR Hekstra Annual review of biophysics 52 (1), 255-274, 2023 | 16 | 2023 |
Native SAD phasing at room temperature JB Greisman, KM Dalton, CJ Sheehan, MA Klureza, I Kurinov, DR Hekstra Acta Crystallographica Section D: Structural Biology 78 (8), 986-996, 2022 | 11 | 2022 |
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism JB Greisman, KM Dalton, DE Brookner, MA Klureza, CJ Sheehan, IS Kim, ... Proceedings of the National Academy of Sciences 121 (9), e2313192121, 2024 | 10 | 2024 |
Trend and fluctuations: Analysis and design of population dynamics measurements in replicate ecosystems DR Hekstra, S Cocco, R Monasson, S Leibler Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 88 (6 …, 2013 | 10 | 2013 |
Correcting systematic errors in diffraction data with modern scaling algorithms LA Aldama, KM Dalton, DR Hekstra Acta Crystallographica Section D: Structural Biology 79 (9), 2023 | 7 | 2023 |
Resolving conformational changes that mediate a two-step catalytic mechanism in a model enzyme JB Greisman, KM Dalton, DE Brookner, MA Klureza, CJ Sheehan, IS Kim, ... bioRxiv, 2023 | 4 | 2023 |
Population dynamics in a model closed ecosystem DR Hekstra | 4 | 2009 |
MatchMaps: non‐isomorphous difference maps for X‐ray crystallography DE Brookner, DR Hekstra Journal of Applied Crystallography, 2024 | 3 | 2024 |