An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where? R Wadhwa, K Taira, SC Kaul Cell stress & chaperones 7 (3), 309, 2002 | 340 | 2002 |
Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor T Nomura, MM Khan, SC Kaul, HD Dong, R Wadhwa, C Colmenares, ... Genes & development 13 (4), 412-423, 1999 | 331 | 1999 |
Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function R Wadhwa, T Sugihara, A Yoshida, H Nomura, RR Reddel, R Simpson, ... Cancer research 60 (24), 6818-6821, 2000 | 302 | 2000 |
Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis R Wadhwa, S Takano, K Kaur, CC Deocaris, OM Pereira‐Smith, ... International journal of cancer 118 (12), 2973-2980, 2006 | 301 | 2006 |
Three faces of mortalin: a housekeeper, guardian and killer SC Kaul, CC Deocaris, R Wadhwa Experimental gerontology 42 (4), 263-274, 2007 | 291 | 2007 |
Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member R Wadhwa, S Takano, M Robert, A Yoshida, H Nomura, RR Reddel, ... Journal of Biological Chemistry 273 (45), 29586-29591, 1998 | 285 | 1998 |
Proteomic Identification of a Stress Protein, Mortalin/mthsp70/GRP75: Relevance To Parkinson Disease* S J Jin, C Hulette, Y Wang, T Zhang, C Pan, R Wadhwa, J Zhang Molecular & Cellular Proteomics 5 (7), 1193-1204, 2006 | 283 | 2006 |
The Ski protein family is required for MeCP2-mediated transcriptional repression K Kokura, SC Kaul, R Wadhwa, T Nomura, MM Khan, T Shinagawa, ... Journal of Biological Chemistry 276 (36), 34115-34121, 2001 | 282 | 2001 |
On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60 CC Deocaris, SC Kaul, R Wadhwa Cell stress & chaperones 11 (2), 116, 2006 | 271 | 2006 |
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75 K Yokoyama, K Fukumoto, T Murakami, S Harada, R Hosono, R Wadhwa, ... FEBS letters 516 (1-3), 53-57, 2002 | 264 | 2002 |
Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype. R Wadhwa, SC Kaul, Y Ikawa, Y Sugimoto Journal of Biological Chemistry 268 (9), 6615-6621, 1993 | 257 | 1993 |
Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein R Wadhwa, T Yaguchi, MK Hasan, Y Mitsui, RR Reddel, SC Kaul Experimental cell research 274 (2), 246-253, 2002 | 229 | 2002 |
Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres ZH Zhong, WQ Jiang, AJ Cesare, AA Neumann, R Wadhwa, RR Reddel Journal of Biological Chemistry 282 (40), 29314-29322, 2007 | 225 | 2007 |
Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect N Widodo, K Kaur, BG Shrestha, Y Takagi, T Ishii, R Wadhwa, SC Kaul Clinical Cancer Research 13 (7), 2298-2306, 2007 | 222 | 2007 |
Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75 Q Ran, R Wadhwa, R Kawai, SC Kaul, RN Sifers, RJ Bick, JR Smith, ... Biochemical and biophysical research communications 275 (1), 174-179, 2000 | 219 | 2000 |
Protective role of Ashwagandha leaf extract and its component withanone on scopolamine-induced changes in the brain and brain-derived cells A Konar, N Shah, R Singh, N Saxena, SC Kaul, R Wadhwa, MK Thakur PloS one 6 (11), e27265, 2011 | 216 | 2011 |
Quantum dots in bio-imaging: revolution by the small H Arya, Z Kaul, R Wadhwa, K Taira, T Hirano, SC Kaul Biochemical and biophysical research communications 329 (4), 1173-1177, 2005 | 204 | 2005 |
Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity V Kumar, JK Dhanjal, SC Kaul, R Wadhwa, D Sundar Journal of Biomolecular Structure and Dynamics 39 (11), 3842-3854, 2021 | 194 | 2021 |
Mortalin–p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy WJ Lu, NP Lee, SC Kaul, F Lan, RTP Poon, R Wadhwa, JM Luk Cell Death & Differentiation 18 (6), 1046-1056, 2011 | 175 | 2011 |
Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling N Widodo, D Priyandoko, N Shah, R Wadhwa, SC Kaul PloS one 5 (10), e13536, 2010 | 172 | 2010 |