Isotype switching converts anti-CD40 antagonism to agonism to elicit potent antitumor activity X Yu, HTC Chan, H Fisher, CA Penfold, J Kim, T Inzhelevskaya, ... Cancer Cell 37 (6), 850-866. e7, 2020 | 58 | 2020 |
Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility CM Orr, H Fisher, X Yu, CHT Chan, Y Gao, PJ Duriez, SG Booth, I Elliott, ... Science immunology 7 (73), eabm3723, 2022 | 30 | 2022 |
Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering F Heckel, AH Turaj, H Fisher, HT Chan, MJE Marshall, O Dadas, ... Communications biology 5 (1), 1-15, 2022 | 14 | 2022 |
Abstract IA03: Optimizing immunostimulatory antibodies for cancer immunotherapy X Yu, A White, M Glennie, I Tews, H Fisher, C Orr, R French, S Beers, ... Blood Cancer Discovery 1 (3_Supplement), IA03-IA03, 2020 | | 2020 |