| Systematic humanization of yeast genes reveals conserved functions and genetic modularity AH Kachroo, JM Laurent, CM Yellman, AG Meyer, CO Wilke, EM Marcotte Science 348 (6237), 921-925, 2015 | 518 | 2015 |
| Efforts to make and apply humanized yeast JM Laurent, JH Young, AH Kachroo, EM Marcotte Briefings in functional genomics 15 (2), 155-163, 2016 | 129 | 2016 |
| Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9 A Akhmetov, JM Laurent, J Gollihar, EC Gardner, RK Garge, AD Ellington, ... Bio-protocol 8 (6), 2018 | 57 | 2018 |
| An overview of tyrosine site‐specific recombination: from an Flp perspective M Jayaram, CH Ma, AH Kachroo, PA Rowley, P Guga, HF Fan, ... Mobile DNA III, 41-71, 2015 | 51 | 2015 |
| Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs JM Laurent, RK Garge, AI Teufel, CO Wilke, AH Kachroo, EM Marcotte PLoS biology 18 (5), e3000627, 2020 | 48 | 2020 |
| Humanized yeast to model human biology, disease and evolution AH Kachroo, M Vandeloo, BM Greco, M Abdullah Disease models & mechanisms 15 (6), dmm049309, 2022 | 37 | 2022 |
| Systematic bacterialization of yeast genes identifies a near-universally swappable pathway. AH Kachroo, JM Laurent, A Akhmetov, M Szilagyi-Jones, CD McWhite, ... eLife 6, 2017 | 37 | 2017 |
| Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose AH Kachroo, AK Kancherla, NS Singh, U Varshney, S Mahadevan Molecular microbiology 66 (6), 1382-1395, 2007 | 36 | 2007 |
| The many nuanced evolutionary consequences of duplicated genes AI Teufel, MM Johnson, JM Laurent, AH Kachroo, EM Marcotte, CO Wilke Molecular biology and evolution 36 (2), 304-314, 2019 | 32 | 2019 |
| The partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells YT Liu, S Sau, CH Ma, AH Kachroo, PA Rowley, KM Chang, HF Fan, ... Microbiology spectrum 2 (5), 10.1128/microbiolspec. plas-0003-2013, 2014 | 26 | 2014 |
| Yeast cells expressing the human mitochondrial DNA polymerase reveal correlations between polymerase fidelity and human disease progression Y Qian, AH Kachroo, CM Yellman, EM Marcotte, KA Johnson Journal of Biological Chemistry 289 (9), 5970-5985, 2014 | 25 | 2014 |
| Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes RK Garge, JM Laurent, AH Kachroo, EM Marcotte Genetics 215 (4), 1153-1169, 2020 | 24 | 2020 |
| Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase CH Ma, AH Kachroo, A Macieszak, TY Chen, P Guga, M Jayaram PLoS One 4 (9), 2009 | 19 | 2009 |
| Metabolic engineering without plasmids AH Kachroo, M Jayaram, PA Rowley nature Biotechnology 27 (8), 729-731, 2009 | 17 | 2009 |
| Functional analysis of the genes encoding diaminopropionate ammonia lyase in Escherichia coli and Salmonella enterica serovar Typhimurium JN Kalyani, N Ramachandra, AH Kachroo, S Mahadevan, HS Savithri Journal of bacteriology 194 (20), 5604-5612, 2012 | 12 | 2012 |
| Electrostatic suppression allows tyrosine site-specific recombination in the absence of a conserved catalytic arginine PA Rowley, AH Kachroo, CH Ma, AD Maciaszek, P Guga, M Jayaram Journal of Biological Chemistry 285 (30), 22976-22985, 2010 | 10 | 2010 |
| Restoration of catalytic functions in Cre recombinase mutants by electrostatic compensation between active site and DNA substrate AH Kachroo, CH Ma, PA Rowley, AD Maciaszek, P Guga, M Jayaram Nucleic acids research 38 (19), 6589-6601, 2010 | 9 | 2010 |
| Humanization of yeast genes with multiple human orthologs reveals principles of functional divergence between paralogs JM Laurent, RK Garge, AI Teufel, CO Wilke, AH Kachroo, EM Marcotte bioRxiv, 668335, 2019 | 7 | 2019 |
| An overview of tyrosine site-specific recombination: from an Flp perspective. Microbiol Spectr. 3 (4), doi: 10.1128/microbiolspec YV M Jayaram, CH Ma, AH Kachroo, PA Rowley, P Guga, HF Fan Microbiology Spectrum, 2015 | 7* | 2015 |
| Discovery of new vascular disrupting agents based on evolutionarily conserved drug action, pesticide resistance mutations, and humanized yeast RK Garge, HJ Cha, C Lee, JD Gollihar, AH Kachroo, JB Wallingford, ... Genetics 219 (1), iyab101, 2021 | 6 | 2021 |
Edward MarcotteProfessor of Molecular Biosciences, University of Texas at Austin在 utexas.edu 的电子邮件经过验证
