Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids M Kasendra, A Tovaglieri, A Sontheimer-Phelps, S Jalili-Firoozinezhad, ... Scientific reports 8 (1), 1-14, 2018 | 654 | 2018 |
Human iPSC-derived blood-brain barrier chips enable disease modeling and personalized medicine applications GD Vatine, R Barrile, MJ Workman, S Sances, BK Barriga, M Rahnama, ... Cell stem cell 24 (6), 995-1005. e6, 2019 | 483 | 2019 |
Human colon-on-a-chip enables continuous in vitro analysis of colon mucus layer accumulation and physiology A Sontheimer-Phelps, DB Chou, A Tovaglieri, TC Ferrante, T Duckworth, ... Cellular and molecular gastroenterology and hepatology 9 (3), 507-526, 2020 | 187 | 2020 |
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model M Kasendra, R Luc, J Yin, DV Manatakis, G Kulkarni, C Lucchesi, J Sliz, ... Elife 9, e50135, 2020 | 171 | 2020 |
Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites A Tovaglieri, A Sontheimer-Phelps, A Geirnaert, R Prantil-Baun, ... Microbiome 7, 1-21, 2019 | 125 | 2019 |
Pathogenic E. coli Exploits SslE Mucinase Activity to Translocate through the Mucosal Barrier and Get Access to Host Cells M Valeri, S Rossi Paccani, M Kasendra, B Nesta, L Serino, M Pizza, ... PloS one 10 (3), e0117486, 2015 | 66 | 2015 |
Lipoprotein CD0873 Is a Novel Adhesin of Clostridium difficile A Kovacs-Simon, R Leuzzi, M Kasendra, N Minton, RW Titball, SL Michell The Journal of infectious diseases 210 (2), 274-284, 2014 | 65 | 2014 |
Clostridium difficile Toxins Facilitate Bacterial Colonization by Modulating the Fence and Gate Function of Colonic Epithelium M Kasendra, R Barrile, R Leuzzi, M Soriani The Journal of infectious diseases 209 (7), 1095-1104, 2014 | 46 | 2014 |
A novel microphysiological colon platform to decipher mechanisms driving human intestinal permeability A Apostolou, RA Panchakshari, A Banerjee, DV Manatakis, ... Cellular and Molecular Gastroenterology and Hepatology 12 (5), 1719-1741, 2021 | 36 | 2021 |
Mechanical stimuli affect Escherichia coli heat-stable enterotoxin-cyclic GMP signaling in a human enteroid intestine-chip model L Sunuwar, J Yin, M Kasendra, K Karalis, J Kaper, J Fleckenstein, ... Infection and immunity 88 (3), 10.1128/iai. 00866-19, 2020 | 36 | 2020 |
Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip J Yin, L Sunuwar, M Kasendra, H Yu, CM Tse, CC Talbot Jr, T Boronina, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 320 (3 …, 2021 | 32 | 2021 |
Neisseria meningitidis subverts the polarized organization and intracellular trafficking of host cells to cross the epithelial barrier R Barrile, M Kasendra, S Rossi‐Paccani, M Merola, M Pizza, C Baldari, ... Cellular microbiology 17 (9), 1365-1375, 2015 | 31 | 2015 |
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids. Sci Rep 8: 2871 M Kasendra, A Tovaglieri, A Sontheimer-Phelps, S Jalili-Firoozinezhad, ... | 22 | 2018 |
Systems and methods for growth of intestinal cells in microfluidic devices SJ Kerns, N Wen, C Lucchesi, CD Hinojosa, J Fraser, J Puerta, ... US Patent 11,326,149, 2022 | 11 | 2022 |
Combining human organoids and organ-on-a-chip technology to model intestinal region-specific functionality G Kulkarni, A Apostolou, L Ewart, C Lucchesi, M Kasendra JoVE (Journal of Visualized Experiments), e63724, 2022 | 7 | 2022 |
Intestinal organoids: roadmap to the clinic M Kasendra, M Troutt, T Broda, WC Bacon, TC Wang, JC Niland, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 321 (1 …, 2021 | 7 | 2021 |
A window into your gut: biologically inspired engineering of mini-gut tubes in vitro M Kasendra, JM Wells Developmental Cell 55 (5), 522-524, 2020 | 5 | 2020 |
In vitro gastrointestinal model comprising lamina propria-derived cells SJ Kerns, J Obrigewitch, M Salmon, M Kasendra, BR Umiker US Patent 11,001,795, 2021 | 3 | 2021 |
Methods relating to intestinal organ-on-a-chip DE Ingber, M Kasendra, A Sontheimer-phelps, A Tovaglieri US Patent App. 16/331,718, 2020 | 3 | 2020 |
Rheologically biomimetic fluid surrogate A Varone, M Kasendra, C Lucchesi, SJ Kerns, R Barrile, S Barthakur US Patent 11,788,044, 2023 | 2 | 2023 |