Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 887 | 2015 |
Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork C Hertweck, A Luzhetskyy, Y Rebets, A Bechthold Natural product reports 24 (1), 162-190, 2007 | 683 | 2007 |
Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 666 | 2021 |
β-Glucuronidase as a sensitive and versatile reporter in actinomycetes M Myronovskyi, E Welle, V Fedorenko, A Luzhetskyy Applied and environmental microbiology 77 (15), 5370-5383, 2011 | 234 | 2011 |
Insights into naturally minimised Streptomyces albus J1074 genome N Zaburannyi, M Rabyk, B Ostash, V Fedorenko, A Luzhetskyy BMC genomics 15, 1-11, 2014 | 205 | 2014 |
Design, construction and characterisation of a synthetic promoter library for fine-tuned gene expression in actinomycetes T Siegl, B Tokovenko, M Myronovskyi, A Luzhetskyy Metabolic engineering 19, 98-106, 2013 | 202 | 2013 |
Generation of a cluster-free Streptomyces albus chassis strains for improved heterologous expression of secondary metabolite clusters M Myronovskyi, B Rosenkränzer, S Nadmid, P Pujic, P Normand, ... Metabolic engineering 49, 316-324, 2018 | 189 | 2018 |
Enabling the valorization of guaiacol-based lignin: Integrated chemical and biochemical production of cis, cis-muconic acid using metabolically engineered Amycolatopsis sp ATCC … N Barton, L Horbal, S Starck, M Kohlstedt, A Luzhetskyy, C Wittmann Metabolic engineering 45, 200-210, 2018 | 147 | 2018 |
Site-specific recombination strategies for engineering actinomycete genomes S Herrmann, T Siegl, M Luzhetska, L Petzke, C Jilg, E Welle, A Erb, ... Applied and environmental microbiology 78 (6), 1804-1812, 2012 | 131 | 2012 |
Native and engineered promoters in natural product discovery M Myronovskyi, A Luzhetskyy Natural product reports 33 (8), 1006-1019, 2016 | 117 | 2016 |
The future of natural products as a source of new antibiotics. A Luzhetskyy, S Pelzer, A Bechthold Current opinion in investigational drugs (London, England: 2000) 8 (8), 608-613, 2007 | 108 | 2007 |
New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp. MP131-18 C Paulus, Y Rebets, B Tokovenko, S Nadmid, LP Terekhova, ... Scientific Reports 7 (1), 42382, 2017 | 106 | 2017 |
Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: analysis of the gene cluster and generation of derivatives C Dürr, HJ Schnell, A Luzhetskyy, R Murillo, M Weber, K Welzel, A Vente, ... Chemistry & biology 13 (4), 365-377, 2006 | 99 | 2006 |
Glycosyltransferases, important tools for drug design A Luzhetskyy, C Mendez, JA Salas, A Bechthold Current topics in medicinal chemistry 8 (8), 680-709, 2008 | 91 | 2008 |
Engineering of Streptomyces lividans for heterologous expression of secondary metabolite gene clusters Y Ahmed, Y Rebets, MR Estévez, J Zapp, M Myronovskyi, A Luzhetskyy Microbial cell factories 19, 1-16, 2020 | 90 | 2020 |
Heterologous production of small molecules in the optimized Streptomyces hosts M Myronovskyi, A Luzhetskyy Natural product reports 36 (9), 1281-1294, 2019 | 87 | 2019 |
Functional expression of the Cre recombinase in actinomycetes M Fedoryshyn, E Welle, A Bechthold, A Luzhetskyy Applied microbiology and biotechnology 78, 1065-1070, 2008 | 86 | 2008 |
Metabolic engineering of natural product biosynthesis in actinobacteria O Bilyk, A Luzhetskyy Current opinion in biotechnology 42, 98-107, 2016 | 84 | 2016 |
Cloning and heterologous expression of the grecocycline biosynthetic gene cluster O Bilyk, ON Sekurova, SB Zotchev, A Luzhetskyy PloS one 11 (7), e0158682, 2016 | 81 | 2016 |
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin R Makitrynskyy, B Ostash, O Tsypik, Y Rebets, E Doud, T Meredith, ... Open biology 3 (10), 130121, 2013 | 78 | 2013 |