Significant structural differences between transient amyloid‐β oligomers and less‐toxic fibrils in regions known to harbor familial alzheimer′ s mutations B Sarkar, VS Mithu, B Chandra, A Mandal, M Chandrakesan, D Bhowmik, ... Angewandte Chemie 126 (27), 7008-7012, 2014 | 111 | 2014 |
Cell-membrane-mimicking lipid-coated nanoparticles confer Raman enhancement to membrane proteins and reveal membrane-attached amyloid-β conformation D Bhowmik, KR Mote, CM MacLaughlin, N Biswas, B Chandra, JK Basu, ... ACS nano 9 (9), 9070-9077, 2015 | 101 | 2015 |
Curcumin alters the salt bridge-containing turn region in amyloid β (1–42) aggregates VS Mithu, B Sarkar, D Bhowmik, AK Das, M Chandrakesan, S Maiti, ... Journal of Biological Chemistry 289 (16), 11122-11131, 2014 | 78 | 2014 |
Zn++ binding disrupts the Asp23-Lys28 salt bridge without altering the hairpin-shaped cross-β structure of Aβ42 amyloid aggregates VS Mithu, B Sarkar, D Bhowmik, M Chandrakesan, S Maiti, PK Madhu Biophysical Journal 101 (11), 2825-2832, 2011 | 74 | 2011 |
An early folding contact between Phe19 and Leu34 is critical for amyloid-β oligomer toxicity AK Das, A Rawat, D Bhowmik, R Pandit, D Huster, S Maiti Acs Chemical Neuroscience 6 (8), 1290-1295, 2015 | 65 | 2015 |
Lattice-Resonance Metalenses for Fully Reconfigurable Imaging J Hu, D Wang, D Bhowmik, T Liu, S Deng, PM Knudson, X Ao, ... ACS Nano 13 (4), 4613-4620, 2019 | 64 | 2019 |
Major reaction coordinates linking transient amyloid-β oligomers to fibrils measured at atomic level B Chandra*, D Bhowmik*, BK Maity, KR Mote, D Dhara, R Venkatramani, ... Biophysical journal 113 (4), 805-816, 2017 | 47 | 2017 |
A folding transition underlies the emergence of membrane affinity in amyloid-β S Nag, B Sarkar, M Chandrakesan, R Abhyanakar, D Bhowmik, ... Physical Chemistry Chemical Physics 15 (44), 19129-19133, 2013 | 45 | 2013 |
Rapid, cell-free assay for membrane-active forms of amyloid-β D Bhowmik, AK Das, S Maiti Langmuir 31 (14), 4049-4053, 2015 | 34 | 2015 |
pH changes the aggregation propensity of amyloid-β without altering the monomer conformation D Bhowmik, CM MacLaughlin, M Chandrakesan, P Ramesh, ... Physical Chemistry Chemical Physics 16 (3), 885-889, 2014 | 33 | 2014 |
Wavelength-Dependent Differential Interference Contrast Inversion of Anisotropic Gold Nanoparticles P Choo, AJ Hryn, KSB Culver, D Bhowmik, J Hu, TW Odom The Journal of Physical Chemistry C 122 (47), 27024-27031, 2018 | 21 | 2018 |
A detailed analysis of the morphology of fibrils of selectively mutated amyloid β (1–40) J Adler, M Baumann, B Voigt, HA Scheidt, D Bhowmik, T Häupl, B Abel, ... ChemPhysChem 17 (17), 2744-2753, 2016 | 20 | 2016 |
Curcumin dictates divergent fates for the central salt bridges in amyloid-β40 and amyloid-β42 B Chandra, VS Mithu, D Bhowmik, AK Das, B Sahoo, S Maiti, PK Madhu Biophysical Journal 112 (8), 1597-1608, 2017 | 19 | 2017 |
The basic structural motif and major biophysical properties of amyloid-β are encoded in the fragment 18–35 M Chandrakesan, B Sarkar, VS Mithu, R Abhyankar, D Bhowmik, S Nag, ... Chemical Physics 422, 80-87, 2013 | 18 | 2013 |
Resolving Single-Nanoconstruct Dynamics during Targeting and Nontargeting Live-Cell Membrane Interactions D Bhowmik, KSB Culver, T Liu, TW Odom ACS Nano, 2019 | 17 | 2019 |
Hypertrophic cardiomyopathy mutations in the pliant and light chain-binding regions of the lever arm of human β-cardiac myosin have divergent effects on myosin function MM Morck, D Bhowmik, D Pathak, A Dawood, J Spudich, KM Ruppel Elife 11, e76805, 2022 | 14 | 2022 |
Steric crowding of the turn region alters the tertiary fold of amyloid-β18–35 and makes it soluble M Chandrakesan*, D Bhowmik*, B Sarkar, R Abhyankar, H Singh, ... Journal of Biological Chemistry 290 (50), 30099-30107, 2015 | 14 | 2015 |
Coexisting Ordered and Disordered Membrane Phases Have Distinct Modes of Interaction with Disease-Associated Oligomers A Gupta, S Dey, D Bhowmik, S Maiti The Journal of Physical Chemistry B 126 (5), 1016-1023, 2022 | 4 | 2022 |
Amyloid diagnostics: probing protein aggregation and conformation with ultrasensitive fluorescence detection R Abhyankar, B Sahoo, NK Singh, LM Meijer, B Sarkar, AK Das, S Nag, ... Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical …, 2012 | 4 | 2012 |
Allosteric destabilization of the super-relaxed state of cardiac myosin by hypertrophic cardiomyopathy-causing mutations N Nandwani, D Bhowmik, A Dawood, K Ruppel, JA Spudich Biophysical Journal 121 (3), 292a, 2022 | 1 | 2022 |