ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxicity induced by soluble oligomers of β-amyloid peptide in hippocampal neurons F Sáez-Orellana, PA Godoy, CY Bastidas, T Silva-Grecchi, L Guzmán, ... Neuropharmacology 100, 116-123, 2016 | 58 | 2016 |
Changes in PGC‐1α/SIRT1 signaling impact on mitochondrial homeostasis in amyloid-beta peptide toxicity model JD Panes, PA Godoy, T Silva-Grecchi, MT Celis, O Ramirez-Molina, ... Frontiers in pharmacology 11, 709, 2020 | 51 | 2020 |
P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease F Sáez-Orellana, MC Fuentes-Fuentes, PA Godoy, T Silva-Grecchi, ... Neuropharmacology 128, 366-378, 2018 | 47 | 2018 |
Exploring the Role of P2X Receptors in Alzheimer’s Disease PA Godoy, OG Ramírez-Molina, J Fuentealba Frontiers in Pharmacology 10, 1330, 2019 | 27 | 2019 |
Modulation of the neuronal network activity by P2X receptors and their involvement in neurological disorders F Saez-Orellana, PA Godoy, T Silva-Grecchi, KM Barra, J Fuentealba Pharmacological research 101, 109-115, 2015 | 27 | 2015 |
17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-β Toxicity by Nicotinic Acetylcholine Receptors J Gavilan, D Mennickent, O Ramirez-Molina, S Triviño, C Perez, ... Journal of Alzheimer's Disease 67 (1), 343-356, 2019 | 15 | 2019 |
Microglial activation modulated by P2X4R in ischemia and repercussions in Alzheimer’s disease C Castillo, F Saez-Orellana, PA Godoy, J Fuentealba Frontiers in Physiology 13, 814999, 2022 | 14 | 2022 |
TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis and synaptic function in Alzheimer’s disease J Panes-Fernandez, PA Godoy, J Gavilan, O Ramírez-Molina, CF Burgos, ... Biomedicine & Pharmacotherapy 162, 114596, 2023 | 8 | 2023 |
Increased P2× 2 receptors induced by amyloid-β peptide participates in the neurotoxicity in alzheimer’s disease PA Godoy, D Mennickent, I Cuchillo-Ibanez, O Ramírez-Molina, ... Biomedicine & Pharmacotherapy 142, 111968, 2021 | 7 | 2021 |
Impact of mitochondrial dysfunction on neurodegenerative diseases: A key step on Alzheimer’s disease T Celis-Muñoz, T Silva-Grecchi, PA Godoy, J Panes-Fernández, K Barra, ... J. Syst. Integr. Neurosci. 2 (3), 166-173, 2016 | 3 | 2016 |
INCREASES CALPAIN-1 LEVELS BY P2X2R ACTIVATION PROMOTE THE AMYLOIDOGENIC PATHWAY AND BETA-AMYLOID PEPTIDE GENERATION. J Gavilan, J Panes, P Godoy, O Ramírez, P Castro, G Yévenes, G Moraga, ... IBRO Neuroscience Reports 15, S413, 2023 | | 2023 |