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Edward C. Twomey
Edward C. Twomey
Johns Hopkins University School of Medicine
在 jhmi.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding
EC Twomey, Z Ji, TE Wales, NO Bodnar, SB Ficarro, JA Marto, JR Engen, ...
Science 365 (6452), eaax1033, 2019
2742019
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
EC Twomey, MV Yelshanskaya, RA Grassucci, J Frank, AI Sobolevsky
Nature 549 (7670), 60-65, 2017
2332017
Opening of the human epithelial calcium channel TRPV6
LL McGoldrick, AK Singh, K Saotome, MV Yelshanskaya, EC Twomey, ...
Nature 553 (7687), 233-237, 2018
1932018
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
EC Twomey, MV Yelshanskaya, RA Grassucci, J Frank, AI Sobolevsky
Science 353 (6924), 83-86, 2016
1362016
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
EC Twomey, MV Yelshanskaya, J Grassucci, R.A., Frank, AI Sobolevsky
Neuron 94 (3), 569-580, 2017
1142017
Structural mechanisms of gating in ionotropic glutamate receptors
EC Twomey, AI Sobolevsky
Biochemistry 57 (3), 267–276, 2018
1132018
Mechanisms of channel block in calcium-permeable AMPA receptors
EC Twomey, MV Yelshanskaya, AA Vassilevski, AI Sobolevsky
Neuron 99 (5), 956-968. e4, 2018
1082018
Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6
AK Singh, LL McGoldrick, EC Twomey, AI Sobolevsky
Science advances 4 (8), eaau6088, 2018
972018
Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes
EC Twomey, MV Yelshanskaya, AI Sobolevsky
Journal of General Physiology 151 (12), 1347-1356, 2019
302019
High-definition NMR structure of PED/PEA-15 death effector domain reveals details of key polar side chain interactions
EC Twomey, Y Wei
Biochemical and Biophysical Research Communications 424 (1), 141-146, 2012
142012
Profound conformational changes of PED/PEA-15 in ERK2 complex revealed by NMR backbone dynamics
EC Twomey, DF Cordasco, Y Wei
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (12), 1382-1393, 2012
102012
Substantial conformational change mediated by charge-triad residues of the death effector domain in protein-protein interactions
EC Twomey, DF Cordasco, SD Kozuch, Y Wei
PLoS One 8 (12), e83421, 2013
72013
Allosteric competition and inhibition in AMPA receptors
WD Hale, A Montaño Romero, CU Gonzalez, V Jayaraman, AY Lau, ...
Nature Structural & Molecular Biology, 1-11, 2024
22024
Aboard the ISS: intersubunit signaling revealed in the p97 ATPase
EC Twomey
Nature Structural & Molecular Biology 28 (7), 538-539, 2021
22021
NMR spectroscopic characterization of death domain superfamily proteins: Structures, dynamics and interactions
Y Wei, EC Twomey
Nuclear Magnetic Resonance (NMR): Theory, Applications and Technology, 83-110, 2014
22014
C-SPAM: an open-source time-resolved specimen vitrification device with light-activated molecules
A Montaño Romero, C Bonin, EC Twomey
IUCrJ 11 (1), 2024
12024
Structure of Transmembrane AMPA Receptor Regulatory Protein Subunit γ2
WD Hale, AM Romero, RL Huganir, EC Twomey
Biorxiv, 2023
12023
Memantine Inhibits Calcium-Permeable AMPA Receptors
E Carrillo, A Montaño Romero, CU Gonzalez, AL Turcu, SR Chen, ...
bioRxiv, 2024.07. 02.601784, 2024
2024
Structural Determinants of Ionotropic Glutamate Receptor Function Revealed by Cryo-electron Microscopy
EC Twomey
Columbia University, 2018
2018
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