Coumarins as modulators of the Keap1/Nrf2/ARE signaling pathway EHM Hassanein, AM Sayed, OE Hussein, AM Mahmoud Oxidative Medicine and Cellular Longevity 2020 (1), 1675957, 2020 | 168 | 2020 |
Engineering of serine protease for improved thermostability and catalytic activity using rational design NM Ashraf, A Krishnagopal, A Hussain, D Kastner, AMM Sayed, YK Mok, ... International journal of biological macromolecules 126, 229-237, 2019 | 65 | 2019 |
Flavonoids-mediated SIRT1 signaling activation in hepatic disorders AM Sayed, EHM Hassanein, SH Salem, OE Hussein, AM Mahmoud Life sciences 259, 118173, 2020 | 42 | 2020 |
Edaravone and acetovanillone upregulate Nrf2 and PI3K/Akt/mTOR signaling and prevent cyclophosphamide cardiotoxicity in rats EHM Hassanein, OAM Abd El-Ghafar, MA Ahmed, AM Sayed, ... Drug Design, Development and Therapy, 5275-5288, 2020 | 37 | 2020 |
Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity FEM Ali, AM Sayed, AH El-Bahrawy, ZMM Omar, EHM Hassanein Life Sciences 275, 119349, 2021 | 31 | 2021 |
Acetovanillone prevents cyclophosphamide‐induced acute lung injury by modulating PI3K/Akt/mTOR and Nrf2 signaling in rats OAM Abd El‐Ghafar, EHM Hassanein, AM Sayed, EK Rashwan, ... Phytotherapy Research, 2021 | 28 | 2021 |
Synthesis of novel biocompatible thienopyrimidine chromophores with aggregation-induced emission sensitive to molecular aggregation M Ahmed, O Younis, EA Orabi, AM Sayed, AM Kamal El-Dean, ... ACS omega 5 (46), 29988-30000, 2020 | 26 | 2020 |
Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological … AM Sayed, EHM Hassanein, FEM Ali, ZMM Omar, EK Rashwan, ... Life sciences 284, 119911, 2021 | 24 | 2021 |
Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: Role of TLR4/NF-κB and c-Fos/c-Jun pro-inflammatory … AM Sayed, MM Abdel-Fattah, HH Arab, WR Mohamed, EHM Hassanein Chemico-biological interactions 351, 109732, 2022 | 22 | 2022 |
The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view EHM Hassanein, WR Mohamed, OS Ahmed, MM Abdel-Daim, AM Sayed Life Sciences 308, 120971, 2022 | 21 | 2022 |
Design, synthesis, biological evaluation, and molecular docking of some new Thieno [2, 3-d] pyrimidine derivatives MS Tolba, AM Sayed, M Sayed, M Ahmed Journal of Molecular Structure 1246, 131179, 2021 | 20 | 2021 |
Ameliorate impacts of scopoletin against vancomycin-induced intoxication in rat model through modulation of Keap1-Nrf2/HO-1 and IκBα-P65 NF-κB/P38 MAPK signaling pathways … MM Khalaf, SM Hassan, AM Sayed, AM Abo-Youssef International Immunopharmacology 102, 108382, 2022 | 19 | 2022 |
Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: Role of Keap‐1/Nrf2/ARE, IL6/STAT‐3, and NF‐κB/AP‐1 signaling pathways OAM Abd El‐Ghafar, EHM Hassanein, FEM Ali, ZMM Omar, EK Rashwan, ... Phytotherapy Research, 2021 | 16 | 2021 |
The promising therapeutic potentials of ginsenosides mediated through p38 MAPK signaling inhibition ESA Arafa, MS Refaey, OAM Abd El-Ghafar, EHM Hassanein, AM Sayed Heliyon 7 (11), 2021 | 15 | 2021 |
Prolyl isomerization of the CENP-A N-terminus regulates centromeric integrity in fission yeast HL Tan, KK Lim, Q Yang, JS Fan, AMM Sayed, LS Low, B Ren, TK Lim, ... Nucleic Acids Research 46 (3), 1167-1179, 2018 | 15 | 2018 |
Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence AGS Shalkami, EHM Hassanein, AM Sayed, WR Mohamed, MM Khalaf, ... Environmental Science and Pollution Research 28, 67593-67607, 2021 | 13 | 2021 |
Regulation of transcriptional silencing and chromodomain protein localization at centromeric heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast B Ren, HL Tan, TTT Nguyen, AMM Sayed, Y Li, YK Mok, H Yang, ... Nucleic Acids Research 46 (1), 189-202, 2018 | 13 | 2018 |
Increased mosquito midgut infection by dengue virus recruitment of plasmin is blocked by an endogenous Kazal-type inhibitor K Ramesh, VA Walvekar, B Wong, AMM Sayed, D Missé, RM Kini, ... Iscience 21, 564-576, 2019 | 12 | 2019 |
Edaravone mitigates hemorrhagic cystitis by modulating Nrf2, TLR‐4/NF‐κB, and JAK1/STAT3 signaling in cyclophosphamide‐intoxicated rats EHM Hassanein, MA Ahmed, AM Sayed, EK Rashwan, ... Journal of Biochemical and Molecular Toxicology 35 (11), e22889, 2021 | 11 | 2021 |
Diallyl disulfide ameliorates methotrexate‐induced nephropathy in rats: Molecular studies and network pharmacology analysis EHM Hassanein, WR Mohamed, MM Khalaf, AGS Shalkami, AM Sayed, ... Journal of Food Biochemistry 45 (6), e13765, 2021 | 11 | 2021 |