| Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer O Levi-Galibov, H Lavon, R Wassermann-Dozorets, M Pevsner-Fischer, ... Nature communications 11 (1), 6245, 2020 | 80 | 2020 |
| Amidino-rocaglates: a potent class of eIF4A inhibitors J Chu, W Zhang, R Cencic, WG Devine, D Beglov, T Henkel, LE Brown, ... Cell chemical biology 26 (11), 1586-1593. e3, 2019 | 78 | 2019 |
| Rocaglates induce gain-of-function alterations to eIF4A and eIF4F J Chu, W Zhang, R Cencic, PBF O’Connor, F Robert, WG Devine, ... Cell reports 30 (8), 2481-2488. e5, 2020 | 75 | 2020 |
| BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling L Shaashua, A Ben-Shmuel, M Pevsner-Fischer, G Friedman, ... Nature communications 13 (1), 6513, 2022 | 46 | 2022 |
| Intercepted retro-Nazarov reaction: syntheses of amidino-rocaglate derivatives and their biological evaluation as eIF4A inhibitors W Zhang, J Chu, AM Cyr, H Yueh, LE Brown, TT Wang, J Pelletier, ... Journal of the American Chemical Society 141 (32), 12891-12900, 2019 | 39 | 2019 |
| A concise total synthesis of dictyodendrins F, H, and I using aryl ynol ethers as key building blocks W Zhang, JM Ready Journal of the American Chemical Society 138 (33), 10684-10692, 2016 | 37 | 2016 |
| Chemical synthesis enables structural reengineering of aglaroxin C leading to inhibition bias for hepatitis C viral infection W Zhang, S Liu, RI Maiga, J Pelletier, LE Brown, TT Wang, JA Porco Jr Journal of the American Chemical Society 141 (3), 1312-1323, 2018 | 35 | 2018 |
| The Ketene‐Surrogate Coupling: Catalytic Conversion of Aryl Iodides into Aryl Ketenes through Ynol Ethers W Zhang, JM Ready Angewandte Chemie 126 (34), 9126-9130, 2014 | 31 | 2014 |
| Total synthesis of the dictyodendrins as an arena to highlight emerging synthetic technologies W Zhang, JM Ready Natural product reports 34 (8), 1010-1034, 2017 | 28 | 2017 |
| Computational analysis of synthetic planning: past and future Z Wang, W Zhang, B Liu Chinese Journal of Chemistry 39 (11), 3127-3143, 2021 | 17 | 2021 |
| Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication DF Praditya, M Klöhn, Y Brüggemann, LE Brown, JA Porco Jr, W Zhang, ... Antiviral research 204, 105359, 2022 | 13 | 2022 |
| Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation R Itoua Maïga, R Cencic, J Chu, DD Waller, LE Brown, WG Devine, ... Scientific Reports 9 (1), 1265, 2019 | 12 | 2019 |
| Racemic and enantioselective total synthesis of heliespirones A & C C Huang, WH Zhang, B Liu Science China Chemistry 54 (1), 43-55, 2011 | 9 | 2011 |
| A forward genetic screen identifies modifiers of rocaglate responsiveness L Shen, L Pugsley, R Cencic, HC Wang, F Robert, SK Naineni, A Sahni, ... Scientific Reports 11 (1), 18516, 2021 | 4 | 2021 |
| Optically Active Allenes from an Allylic Substitution/Isomerization Sequence. W Zhang, JM Ready ChemCatChem 5 (12), 2013 | 3 | 2013 |
| Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis PT Keiser, W Zhang, M Ricca, A Wacquiez, A Grimins, R Cencic, JJ Patten, ... Antiviral Research 230, 105976, 2024 | | 2024 |
| Heterocyclic Inhibitors of KRAS G12C Mutant Proteins and Uses Thereof BA Lanman, S Booker, JR Butler, E Glibstrup, D Huang, BW Husemoen, ... WO Patent 2024/076,674, 2024 | | 2024 |
| Heterocyclic Inhibitors of KRAS G12C Mutant Proteins and Uses Thereof BA Lanman, S Booker, JR Butler, E Glibstrup, D Huang, BW Husemoen, ... WO Patent 2024/076,672, 2024 | | 2024 |
| Tethered Heterocyclic Inhibitors of KRAS G12C Mutant Proteins and Uses Thereof BA Lanman, A Alafate, A Banerjee, E Glibstrup, I Hot, D Huang, ... WO Patent 2024/076,670, 2024 | | 2024 |
| Compositions and methods for inhibiting viral infection JA Porco, W Zhang, TT Wang, S Liu US Patent 11,427,595, 2022 | | 2022 |
Jennifer Chu在 mit.edu 的电子邮件经过验证
Jennifer Chu在 mit.edu 的电子邮件经过验证
Sandor VajdaProfessor of Biomedical Engineering, Boston University在 bu.edu 的电子邮件经过验证