Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer APDA Bom, LP Rangel, DCF Costa, GAP de Oliveira, D Sanches, ... Journal of Biological Chemistry 287 (33), 28152-28162, 2012 | 303 | 2012 |
Crystal structure of the platelet activator convulxin, a disulfide-linked α4β4 cyclic tetramer from the venom of Crotalus durissus terrificus MT Murakami, SP Zela, LM Gava, S Michelan-Duarte, ACO Cintra, ... Biochemical and biophysical research communications 310 (2), 478-482, 2003 | 71 | 2003 |
Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments AJC Quaresma, GC Bressan, LM Gava, DCF Lanza, CHI Ramos, ... Experimental cell research 315 (6), 968-980, 2009 | 45 | 2009 |
Structural studies of human purine nucleoside phosphorylase: towards a new specific empirical scoring function LFSM Timmers, RA Caceres, AL Vivan, LM Gava, R Dias, RG Ducati, ... Archives of biochemistry and biophysics 479 (1), 28-38, 2008 | 42 | 2008 |
From conformation to interaction: techniques to explore the Hsp70/Hsp90 network F AH Batista, L M Gava, G MS Pinheiro, C HI Ramos, J C Borges Current Protein and Peptide Science 16 (8), 735-753, 2015 | 30 | 2015 |
Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell-and apicomplexan parasite-mediated diseases RG Silva, JE S Nunes, F Canduri, JC Borges, LM Gava, FB Moreno, ... Current drug targets 8 (3), 413-422, 2007 | 26 | 2007 |
Aspergillus fumigatus Hsp90 interacts with the main components of the cell wall integrity pathway and cooperates in heat shock and cell wall stress adaptation MC Rocha, K Minari, JHTM Fabri, JD Kerkaert, LM Gava, AF da Cunha, ... Cellular microbiology 23 (2), e13273, 2021 | 25 | 2021 |
The C-terminal region of the human p23 chaperone modulates its structure and function TV Seraphim, LM Gava, DZ Mokry, TC Cagliari, LRS Barbosa, CHI Ramos, ... Archives of biochemistry and biophysics 565, 57-67, 2015 | 25 | 2015 |
Stoichiometry and thermodynamics of the interaction between the C-terminus of human 90 kDa heat shock protein Hsp90 and the mitochondrial translocase of outer membrane Tom70 LM Gava, DC Gonçalves, JC Borges, CHI Ramos Archives of biochemistry and biophysics 513 (2), 119-125, 2011 | 21 | 2011 |
Human 90 kDa heat shock protein Hsp90 as a target for cancer therapeutics LM Gava, CHI Ramos Current Chemical Biology 3 (1), 10-21, 2009 | 21 | 2009 |
Structural studies of the Trypanosoma cruzi Old Yellow Enzyme: insights into enzyme dynamics and specificity MT Murakami, NC Rodrigues, LM Gava, RV Honorato, F Canduri, ... Biophysical chemistry 184, 44-53, 2013 | 19 | 2013 |
Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes TV Seraphim, N Nano, YWS Cheung, S Aluksanasuwan, C Colleti, ... Structure 30 (1), 156-171. e12, 2022 | 18 | 2022 |
Structural and functional studies of the Leishmania braziliensis SGT co-chaperone indicate that it shares structural features with HIP and can interact with both Hsp90 and … ALS Coto, TV Seraphim, FAH Batista, PR Dores-Silva, ABF Barranco, ... International journal of biological macromolecules 118, 693-706, 2018 | 18 | 2018 |
Immunization with recombinant enolase of Sporothrix spp. (rSsEno) confers effective protection against sporotrichosis in mice DL Portuondo, PR Dores-Silva, LS Ferreira, CS de Oliveira, ... Scientific Reports 9 (1), 17179, 2019 | 17 | 2019 |
Thermodynamic analysis of interactions of the Hsp90 with adenosine nucleotides: a comparative perspective K Minari, ÉC de Azevedo, VTR Kiraly, FAH Batista, FR de Moraes, ... International journal of biological macromolecules 130, 125-138, 2019 | 16 | 2019 |
Human mitochondrial import receptor Tom70 functions as a monomer ACY Fan, LM Gava, CHI Ramos, JC Young Biochemical journal 429 (3), 553-563, 2010 | 14 | 2010 |
Human Hsp70/Hsp90 organizing protein (Hop) D456G is a mixture of monomeric and dimeric species DC Gonçalves, LM Gava, CHI Ramos Protein and Peptide Letters 17 (4), 492-498, 2010 | 11 | 2010 |
Crystal structure and molecular dynamics studies of human purine nucleoside phosphorylase complexed with 7-deazaguanine RA Caceres, LFSM Timmers, I Pauli, LM Gava, RG Ducati, LA Basso, ... Journal of structural biology 169 (3), 379-388, 2010 | 9 | 2010 |
DNA and heparin chaperone the refolding of purified recombinant replication protein A subunit 1 from Leishmania amazonensis CBB Lira, KE Gui, AM Perez, RCV da Silveira, LM Gava, CHI Ramos, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (2), 119-125, 2009 | 9 | 2009 |
Crystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA2 from Bothrops asper venom MT Murakami, LM Gava, SP Zela, EZ Arruda, PA Melo, JM Gutierrez, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1703 (1), 83-85, 2004 | 9 | 2004 |