| Targeting InhA, the FASII enoyl-ACP reductase: SAR studies on novel inhibitor scaffolds P Pan, P J Tonge Current topics in medicinal chemistry 12 (7), 672-693, 2012 | 98 | 2012 |
| A Structural and Energetic Model for the Slow-Onset Inhibition of the Mycobacterium tuberculosis Enoyl-ACP Reductase InhA HJ Li, CT Lai, P Pan, W Yu, N Liu, GR Bommineni, M Garcia-Diaz, ... ACS chemical biology 9 (4), 986-993, 2014 | 85 | 2014 |
| Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor J Schiebel, A Chang, S Shah, Y Lu, L Liu, P Pan, MW Hirschbeck, ... Journal of Biological Chemistry 289 (23), 15987-16005, 2014 | 77 | 2014 |
| Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the Staphylococcus aureus FabI Enzyme–Product Complex A Chang, J Schiebel, W Yu, GR Bommineni, P Pan, MV Baxter, A Khanna, ... Biochemistry 52 (24), 4217-4228, 2013 | 75 | 2013 |
| Time‐Dependent Diaryl Ether Inhibitors of InhA: Structure–Activity Relationship Studies of Enzyme Inhibition, Antibacterial Activity, and in vivo Efficacy P Pan, SE Knudson, GR Bommineni, HJ Li, CT Lai, N Liu, M Garcia‐Diaz, ... ChemMedChem 9 (4), 776-791, 2014 | 67 | 2014 |
| Inorganic phosphorus fractionation and its translocation dynamics in a low-P soil JC Yang, ZG Wang, J Zhou, HM Jiang, JF Zhang, P Pan, Z Han, C Lu, ... Journal of environmental radioactivity 112, 64-69, 2012 | 63 | 2012 |
| Regioselective modification of amino groups in aminoglycosides based on cyclic carbamate formation G Chen, P Pan, Y Yao, Y Chen, X Meng, Z Li Tetrahedron 64 (38), 9078-9087, 2008 | 23 | 2008 |
| Selective deprotection of the Cbz amine protecting group for the facile synthesis of kanamycin A dimers linked at N-3 ″position GH Chen, P Pan, Y Chen, XB Meng, ZJ Li Tetrahedron 65 (31), 5922-5927, 2009 | 20 | 2009 |
| Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase C Neckles, A Pschibul, CT Lai, M Hirschbeck, J Kuper, S Davoodi, J Zou, ... Biochemistry 55 (21), 2992-3006, 2016 | 11 | 2016 |
| Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase H Wang, L Liu, Y Lu, P Pan, JM Hooker, JS Fowler, PJ Tonge Bioorganic & medicinal chemistry letters 25 (21), 4782-4786, 2015 | 11 | 2015 |
| Formulation studies of InhA inhibitors and combination therapy to improve efficacy against Mycobacterium tuberculosis SE Knudson, JE Cummings, GR Bommineni, P Pan, PJ Tonge, ... Tuberculosis 101, 8-14, 2016 | 7 | 2016 |
| Lead Optimization and Slow-Onset Inhibition of the Enoyl-ACP Reductase (InhA) from Mycobacterium Tuberculosis P Pan State University of New York at Stony Brook, 2012 | 6 | 2012 |
| Time-dependent diaryl ether inhibitors of InhA: SAR studies of enzyme inhibition, antibacterial activity, and in vivo efficacy P Pan, S Knudson, GR Bommineni, HJ Li, CT Lai, N Liu, M Garcia-Diaz, ... ChemMedChem 9 (4), 776, 2014 | 1 | 2014 |
| Slow inhibition of InhA by diphenyl ethers: Conformational states and structural mechanism HJ Li, CT Lai, P Pan, M Garcia-Diaz, C Simmerling, PJ Tonge ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011 | 1 | 2011 |
| Selective protection of ribostamycin by cyclic carbamates P Pan, G Chen, Y Chen, X Meng, Z Li, J Cui JOURNAL OF CHINESE PHARMACEUTICAL SCIENCES 16 (4), 272, 2007 | 1 | 2007 |
| Pyridone FabI inhibitors and uses thereof P Tonge, P Pan US Patent 10,071,965, 2018 | | 2018 |
| Abstract LB-263: Effects of black raspberry diet on the metabolomic profile of C57BL/6J mouse tissues CW Skaer, P Pan, M Young, HT Wang, K Oshima, YW Huang, GD Stoner, ... Cancer Research 75 (15_Supplement), LB-263-LB-263, 2015 | | 2015 |
| Rational modulation of inhibitor binding kinetics: Controlling the key interactions for the slow-onset inhibition of the mycobacterium tuberculosis enoyl-ACP reductase InhA CTE Lai, HJ Li, P Pan, W Yu, N Liu, PJ Tonge, C Simmerling ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
| Cover Picture: Time‐Dependent Diaryl Ether Inhibitors of InhA: Structure–Activity Relationship Studies of Enzyme Inhibition, Antibacterial Activity, and in vivo Efficacy … P Pan, SE Knudson, GR Bommineni, HJ Li, CT Lai, N Liu, M Garcia‐Diaz, ... ChemMedChem 9 (4), 673-673, 2014 | | 2014 |
| Rational modulation of enzyme-inhibitor residence time for the mycobacterium tuberculosisenoyl-ACP reductase InhA CT Lai, P Pan, N Liu, W Yu, L Spagnuolo, S Shah, GR Bommineni, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
Carlos SimmerlingMarsha Laufer Chair in Physical & Quantitative Biology, SUNY Stony Brook在 stonybrook.edu 的电子邮件经过验证
