In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RMC Rivera, ... Science 351 (6271), 403-407, 2016 | 1327 | 2016 |
Adeno-associated virus serotypes: vector toolkit for human gene therapy Z Wu, A Asokan, RJ Samulski Molecular therapy 14 (3), 316-327, 2006 | 1177 | 2006 |
The AAV vector toolkit: poised at the clinical crossroads A Asokan, DV Schaffer, RJ Samulski Molecular Therapy 20 (4), 699-708, 2012 | 562 | 2012 |
Aquaporin-4-dependent glymphatic solute transport in the rodent brain H Mestre, LM Hablitz, ALR Xavier, W Feng, W Zou, T Pu, H Monai, ... Elife 7, e40070, 2018 | 486 | 2018 |
Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, ... Nature medicine 25 (3), 427-432, 2019 | 396 | 2019 |
Terminal N-linked galactose is the primary receptor for adeno-associated virus 9 S Shen, KD Bryant, SM Brown, SH Randell, A Asokan Journal of Biological Chemistry 286 (15), 13532-13540, 2011 | 319 | 2011 |
Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles W Li, A Asokan, Z Wu, T Van Dyke, N DiPrimio, JS Johnson, ... Molecular Therapy 16 (7), 1252-1260, 2008 | 306 | 2008 |
Optical control of CRISPR/Cas9 gene editing J Hemphill, EK Borchardt, K Brown, A Asokan, A Deiters Journal of the American Chemical Society 137 (17), 5642-5645, 2015 | 285 | 2015 |
Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle A Asokan, JC Conway, JL Phillips, C Li, J Hegge, R Sinnott, S Yadav, ... Nature biotechnology 28 (1), 79-82, 2010 | 281 | 2010 |
Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer N Pulicherla, S Shen, S Yadav, K Debbink, L Govindasamy, ... Molecular Therapy 19 (6), 1070-1078, 2011 | 279 | 2011 |
Adeno-associated virus type 2 contains an integrin α5β1 binding domain essential for viral cell entry A Asokan, JB Hamra, L Govindasamy, M Agbandje-McKenna, ... Journal of virology 80 (18), 8961-8969, 2006 | 272 | 2006 |
Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes Z Wu, A Asokan, JC Grieger, L Govindasamy, M Agbandje-McKenna, ... Journal of virology 80 (22), 11393-11397, 2006 | 271 | 2006 |
Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion LV Tse, KA Klinc, VJ Madigan, RM Castellanos Rivera, LF Wells, ... Proceedings of the National Academy of Sciences 114 (24), E4812-E4821, 2017 | 216 | 2017 |
Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia C Li, N Narkbunnam, RJ Samulski, A Asokan, G Hu, LJ Jacobson, ... Gene therapy 19 (3), 288-294, 2012 | 214 | 2012 |
Biology of adeno-associated viral vectors in the central nervous system G Murlidharan, RJ Samulski, A Asokan Frontiers in molecular neuroscience 7, 76, 2014 | 204 | 2014 |
Exploitation of intracellular pH gradients in the cellular delivery of macromolecules A Asokan, MJ Cho Journal of pharmaceutical sciences 91 (4), 903-913, 2002 | 185 | 2002 |
Resolving adeno-associated viral particle diversity with charge detection mass spectrometry EE Pierson, DZ Keifer, A Asokan, MF Jarrold Analytical chemistry 88 (13), 6718-6725, 2016 | 166 | 2016 |
Biophysical and ultrastructural characterization of adeno-associated virus capsid uncoating and genome release ED Horowitz, KS Rahman, BD Bower, DJ Dismuke, MR Falvo, JD Griffith, ... Journal of virology 87 (6), 2994-3002, 2013 | 134 | 2013 |
Bocavirus episome in infected human tissue contains non-identical termini A Kapoor, M Hornig, A Asokan, B Williams, JA Henriquez, WI Lipkin PloS one 6 (6), e21362, 2011 | 120 | 2011 |
Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles C Li, N Diprimio, DE Bowles, ML Hirsch, PE Monahan, A Asokan, ... Journal of virology 86 (15), 7752-7759, 2012 | 118 | 2012 |