Propagation of tau misfolding from the outside to the inside of a cell B Frost, RL Jacks, MI Diamond Journal of Biological Chemistry 284 (19), 12845-12852, 2009 | 1363 | 2009 |
Prion-like mechanisms in neurodegenerative diseases B Frost, MI Diamond Nature Reviews Neuroscience 11 (3), 155-159, 2010 | 839 | 2010 |
Tau promotes neurodegeneration through global chromatin relaxation B Frost, M Hemberg, J Lewis, MB Feany Nature neuroscience 17 (3), 357-366, 2014 | 450 | 2014 |
Conformational diversity of wild-type Tau fibrils specified by templated conformation change B Frost, J Ollesch, H Wille, MI Diamond Journal of Biological Chemistry 284 (6), 3546-3551, 2009 | 261 | 2009 |
A brief overview of tauopathy: causes, consequences, and therapeutic strategies ME Orr, AC Sullivan, B Frost Trends in pharmacological sciences 38 (7), 637-648, 2017 | 241 | 2017 |
Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies W Sun, H Samimi, M Gamez, H Zare, B Frost Nature neuroscience 21 (8), 1038-1048, 2018 | 226 | 2018 |
Lamin dysfunction mediates neurodegeneration in tauopathies B Frost, FH Bardai, MB Feany Current Biology 26 (1), 129-136, 2016 | 213 | 2016 |
Connecting the dots between tau dysfunction and neurodegeneration B Frost, J Götz, MB Feany Trends in cell biology 25 (1), 46-53, 2015 | 144 | 2015 |
Alzheimer's disease: An acquired neurodegenerative laminopathy B Frost Nucleus 7 (3), 275-283, 2016 | 86 | 2016 |
p53 prevents neurodegeneration by regulating synaptic genes P Merlo, B Frost, S Peng, YJ Yang, PJ Park, M Feany Proceedings of the National Academy of Sciences 111 (50), 18055-18060, 2014 | 77 | 2014 |
Pomegranate extract decreases oxidative stress and alleviates mitochondrial impairment by activating AMPK-Nrf2 in hypothalamic paraventricular nucleus of spontaneously … W Sun, C Yan, B Frost, X Wang, C Hou, M Zeng, H Gao, Y Kang, J Liu Scientific reports 6 (1), 34246, 2016 | 75 | 2016 |
Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology SK Dehkordi, J Walker, E Sah, E Bennett, F Atrian, B Frost, B Woost, ... Nature aging 1 (12), 1107-1116, 2021 | 66 | 2021 |
Tau‐induced nuclear envelope invagination causes a toxic accumulation of mRNA in Drosophila GL Cornelison, SA Levy, T Jenson, B Frost Aging cell 18 (1), e12847, 2019 | 61 | 2019 |
Oleuropein, unexpected benefits! W Sun, B Frost, J Liu Oncotarget 8 (11), 17409, 2017 | 57 | 2017 |
Current directions in tau research: Highlights from Tau 2020 C Sexton, H Snyder, D Beher, AL Boxer, P Brannelly, JP Brion, L Buée, ... Alzheimer's & Dementia 18 (5), 988-1007, 2022 | 55 | 2022 |
The expanding realm of prion phenomena in neurodegenerative disease B Frost, MI Diamond Prion 3 (2), 74-77, 2009 | 49 | 2009 |
Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system P Ramirez, G Zuniga, W Sun, A Beckmann, E Ochoa, SL DeVos, B Hyman, ... Progress in neurobiology 208, 102181, 2022 | 46 | 2022 |
Pathogenic tau causes a toxic depletion of nuclear calcium R Mahoney, EO Thomas, P Ramirez, HE Miller, A Beckmann, G Zuniga, ... Cell reports 32 (2), 2020 | 30 | 2020 |
Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model KM Lohr, B Frost, C Scherzer, MB Feany Proceedings of the National Academy of Sciences 117 (52), 33608-33618, 2020 | 27 | 2020 |
Genome-wide association study and functional validation implicates JADE1 in tauopathy K Farrell, SH Kim, N Han, MA Iida, EM Gonzalez, M Otero-Garcia, ... Acta neuropathologica 143, 33-53, 2022 | 23 | 2022 |