It takes two to tango: regulation of G proteins by dimerization R Gasper, S Meyer, K Gotthardt, M Sirajuddin, A Wittinghofer Nature reviews Molecular cell biology 10 (6), 423-429, 2009 | 339 | 2009 |
The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3 S Veltel, R Gasper, E Eisenacher, A Wittinghofer Nature structural & molecular biology 15 (4), 373-380, 2008 | 187 | 2008 |
Structural insights into HypB, a GTP-binding protein that regulates metal binding R Gasper, A Scrima, A Wittinghofer Journal of Biological Chemistry 281 (37), 27492-27502, 2006 | 177 | 2006 |
Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin G Nass Kovacs, JP Colletier, ML Grünbein, Y Yang, T Stensitzki, A Batyuk, ... Nature communications 10 (1), 3177, 2019 | 156 | 2019 |
Dirigent protein mode of action revealed by the crystal structure of AtDIR6 R Gasper, I Effenberger, P Kolesinski, B Terlecka, E Hofmann, A Schaller Plant Physiology 172 (4), 2165-2175, 2016 | 77 | 2016 |
The Ras switch in structural and historical perspective R Gasper, F Wittinghofer Biological chemistry 401 (1), 143-163, 2019 | 69 | 2019 |
Insights into the Biosynthesis and Assembly of Cryptophycean Phycobiliproteins♦ KE Overkamp, R Gasper, K Kock, C Herrmann, E Hofmann, ... Journal of Biological Chemistry 289 (39), 26691-26707, 2014 | 53 | 2014 |
A protein tertiary structure mimetic modulator of the Hippo signalling pathway H Adihou, R Gopalakrishnan, T Förster, SM Guéret, R Gasper, ... Nature Communications 11 (1), 5425, 2020 | 44 | 2020 |
RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP‐binding proteins and mediate Rap2‐specific nucleotide exchange E Yaman, R Gasper, C Koerner, A Wittinghofer, UH Tazebay The FEBS journal 276 (16), 4607-4616, 2009 | 44 | 2009 |
The role of the conserved switch II glutamate in guanine nucleotide exchange factor-mediated nucleotide exchange of GTP-binding proteins R Gasper, C Thomas, MR Ahmadian, A Wittinghofer Journal of molecular biology 379 (1), 51-63, 2008 | 40 | 2008 |
Green fluorescent protein-based expression screening of membrane proteins in Escherichia coli LE Bird, H Rada, A Verma, R Gasper, J Birch, M Jennions, J Lӧwe, ... JoVE (Journal of Visualized Experiments), e52357, 2015 | 39 | 2015 |
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation K Fitzian, A Brückner, L Brohée, R Zech, C Antoni, S Kiontke, R Gasper, ... Molecular cell 81 (13), 2705-2721. e8, 2021 | 34 | 2021 |
Distinct features of cyanophage-encoded T-type phycobiliprotein lyase ΦCpeT: The role of auxiliary metabolic genes R Gasper, J Schwach, J Hartmann, A Holtkamp, J Wiethaus, N Riedel, ... Journal of Biological Chemistry 292 (8), 3089-3098, 2017 | 27 | 2017 |
GTPase activity of Di-Ras proteins is stimulated by Rap1GAP proteins R Gasper, B Sot, A Wittinghofer Small GTPases 1 (3), 133-141, 2010 | 27 | 2010 |
Evolved, selective erasers of distinct lysine acylations M Spinck, P Neumann‐Staubitz, M Ecke, R Gasper, H Neumann Angewandte Chemie International Edition 59 (27), 11142-11149, 2020 | 25 | 2020 |
Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5–MEP50 Complex A Krzyzanowski, R Gasper, H Adihou, P Hart, H Waldmann Chembiochem 22 (11), 1908-1914, 2021 | 18 | 2021 |
Small molecules antagonise the MIA-fibronectin interaction in Malignant melanoma KT Yip, XY Zhong, N Seibel, S Pütz, J Autzen, R Gasper, E Hofmann, ... Scientific Reports 6 (1), 25119, 2016 | 17 | 2016 |
Identification of a novel pseudo‐natural product type IV IDO1 inhibitor chemotype C Davies, L Dötsch, MG Ciulla, E Hennes, K Yoshida, R Gasper, R Scheel, ... Angewandte Chemie 134 (40), e202209374, 2022 | 16 | 2022 |
Synthesis and evaluation of RNase L-binding 2-aminothiophenes as anticancer agents J Hwang, X Qiu, L Borgelt, N Haacke, L Kanis, S Petroulia, R Gasper, ... Bioorganic & Medicinal Chemistry 58, 116653, 2022 | 14 | 2022 |
Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation G Niggemeyer, A Knyazeva, R Gasper, D Corkery, P Bodenbinder, ... Angewandte Chemie International Edition 61 (11), e202114328, 2022 | 13 | 2022 |