Targeting folate receptor alpha for cancer treatment A Cheung, HJ Bax, DH Josephs, KM Ilieva, G Pellizzari, J Opzoomer, ... Oncotarget 7 (32), 52553, 2016 | 461 | 2016 |
Combining immune checkpoint inhibitors: established and emerging targets and strategies to improve outcomes in melanoma DO Khair, HJ Bax, S Mele, S Crescioli, G Pellizzari, A Khiabany, ... Frontiers in immunology 10, 453, 2019 | 243 | 2019 |
IgG4 subclass antibodies impair antitumor immunity in melanoma P Karagiannis, AE Gilbert, DH Josephs, N Ali, T Dodev, L Saul, I Correa, ... The Journal of clinical investigation 123 (4), 1457-1474, 2013 | 232 | 2013 |
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ... Cancer cell 39 (11), 1497-1518. e11, 2021 | 184 | 2021 |
Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs) RM Hoffmann, BGT Coumbe, DH Josephs, S Mele, KM Ilieva, A Cheung, ... Oncoimmunology 7 (3), e1395127, 2018 | 165 | 2018 |
Regional activation of myosin II in cancer cells drives tumor progression via a secretory cross-talk with the immune microenvironment M Georgouli, C Herraiz, E Crosas-Molist, B Fanshawe, O Maiques, ... Cell 176 (4), 757-774. e23, 2019 | 164 | 2019 |
Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers SA Harding, J Sarma, DH Josephs, NL Cruden, JN Din, PJ Twomey, ... Circulation 109 (16), 1926-1929, 2004 | 160 | 2004 |
Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action ZN Willsmore, BGT Coumbe, S Crescioli, S Reci, A Gupta, RJ Harris, ... European Journal of Immunology 51 (3), 544-556, 2021 | 146 | 2021 |
A tool kit for rapid cloning and expression of recombinant antibodies TS Dodev, P Karagiannis, AE Gilbert, DH Josephs, H Bowen, LK James, ... Scientific reports 4 (1), 5885, 2014 | 123 | 2014 |
BRAF inhibitors: resistance and the promise of combination treatments for melanoma M Griffin, D Scotto, DH Josephs, S Mele, S Crescioli, HJ Bax, G Pellizzari, ... Oncotarget 8 (44), 78174, 2017 | 114 | 2017 |
Epidemiological associations of allergy, IgE and cancer DH Josephs, JF Spicer, CJ Corrigan, HJ Gould, SN Karagiannis Clinical & Experimental Allergy 43 (10), 1110-1123, 2013 | 111 | 2013 |
Clinical pharmacokinetics of tyrosine kinase inhibitors: implications for therapeutic drug monitoring DH Josephs, DS Fisher, J Spicer, RJ Flanagan Therapeutic drug monitoring 35 (5), 562-587, 2013 | 104 | 2013 |
Effects of BRAF Mutations and BRAF Inhibition on Immune Responses to Melanoma KM Ilieva, I Correa, DH Josephs, P Karagiannis, IU Egbuniwe, ... Molecular cancer therapeutics 13 (12), 2769-2783, 2014 | 100 | 2014 |
AllergoOncology–the impact of allergy in oncology: EAACI position paper E Jensen‐Jarolim, HJ Bax, R Bianchini, M Capron, C Corrigan, M Castells, ... Allergy 72 (6), 866-887, 2017 | 95 | 2017 |
Flow cytometric analysis of circulating platelet-monocyte aggregates in whole blood: methodological considerations SA Harding, JN Din, J Sarma, A Jessop, M Weatherall, KAA Fox, ... Thrombosis and haemostasis 98 (08), 451-456, 2007 | 95 | 2007 |
Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies AE Gilbert, P Karagiannis, T Dodev, A Koers, K Lacy, DH Josephs, ... PloS one 6 (4), e19330, 2011 | 94 | 2011 |
Anti-folate receptor alpha–directed antibody therapies restrict the growth of triple-negative breast cancer A Cheung, J Opzoomer, KM Ilieva, P Gazinska, RM Hoffmann, H Mirza, ... Clinical Cancer Research 24 (20), 5098-5111, 2018 | 83 | 2018 |
An automated method for the measurement of a range of tyrosine kinase inhibitors in human plasma or serum using turbulent flow liquid chromatography–tandem mass spectrometry L Couchman, M Birch, R Ireland, A Corrigan, S Wickramasinghe, ... Analytical and Bioanalytical Chemistry 403, 1685-1695, 2012 | 83 | 2012 |
Tumour-associated macrophage polarisation and re-education with immunotherapy DH Josephs, HJ Bax, SN Karagiannis Front Biosci (Elite Ed) 7 (2), 293-308, 2015 | 81 | 2015 |
Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNFα/MCP-1 signaling DH Josephs, HJ Bax, T Dodev, M Georgouli, M Nakamura, G Pellizzari, ... Cancer research 77 (5), 1127-1141, 2017 | 79 | 2017 |