| The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion PE MacDonald, W El-Kholy, MJ Riedel, AMF Salapatek, PE Light, ... Diabetes 51 (suppl_3), S434-S442, 2002 | 713 | 2002 |
| Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility J Nagendran, SL Archer, D Soliman, V Gurtu, R Moudgil, A Haromy, ... Circulation 116 (3), 238-248, 2007 | 607 | 2007 |
| 2-Aminoadipic acid is a biomarker for diabetes risk TJ Wang, D Ngo, N Psychogios, A Dejam, MG Larson, RS Vasan, ... The Journal of clinical investigation 123 (10), 4309-4317, 2013 | 454 | 2013 |
| Upper intestinal lipids trigger a gut–brain–liver axis to regulate glucose production PYT Wang, L Caspi, CKL Lam, M Chari, X Li, PE Light, R Gutierrez-Juarez, ... Nature 452 (7190), 1012-1016, 2008 | 370 | 2008 |
| Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt AYM Chan, VW Dolinsky, CLM Soltys, B Viollet, S Baksh, PE Light, ... Journal of Biological Chemistry 283 (35), 24194-24201, 2008 | 274 | 2008 |
| Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1 VW Dolinsky, AYM Chan, I Robillard Frayne, PE Light, C Des Rosiers, ... Circulation 119 (12), 1643-1652, 2009 | 265 | 2009 |
| Glucagon-like peptide-1 inhibits pancreatic ATP-sensitive potassium channels via a protein kinase A-and ADP-dependent mechanism PE Light, JE Manning Fox, MJ Riedel, MB Wheeler Molecular endocrinology 16 (9), 2135-2144, 2002 | 236 | 2002 |
| Protein Kinase C–Induced Changes in the Stoichiometry of ATP Binding Activate Cardiac ATP-Sensitive K+ Channels: A Possible Mechanistic Link to Ischemic … PE Light, AA Sabir, BG Allen, MP Walsh, RJ French Circulation research 79 (3), 399-406, 1996 | 188 | 1996 |
| Empagliflozin blunts worsening cardiac dysfunction associated with reduced NLRP3 (nucleotide-binding domain-like receptor protein 3) inflammasome activation in heart failure NJ Byrne, N Matsumura, ZH Maayah, M Ferdaoussi, S Takahara, ... Circulation: Heart Failure 13 (1), e006277, 2020 | 180 | 2020 |
| Molecular basis of protein kinase C-induced activation of ATP-sensitive potassium channels PE Light, C Bladen, RJ Winkfein, MP Walsh, RJ French Proceedings of the National Academy of Sciences 97 (16), 9058-9063, 2000 | 179 | 2000 |
| Ranolazine decreases diastolic calcium accumulation caused by ATX-II or ischemia in rat hearts H Fraser, L Belardinelli, L Wang, PE Light, JJ McVeigh, AS Clanachan Journal of molecular and cellular cardiology 41 (6), 1031-1038, 2006 | 159 | 2006 |
| Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators M Baghelani, Z Abbasi, M Daneshmand, PE Light Scientific Reports 10 (1), 12980, 2020 | 143 | 2020 |
| Cardiac late sodium channel current is a molecular target for the sodium/glucose cotransporter 2 inhibitor empagliflozin K Philippaert, S Kalyaanamoorthy, M Fatehi, W Long, S Soni, NJ Byrne, ... Circulation 143 (22), 2188-2204, 2021 | 142 | 2021 |
| Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K+ channel KSC Hamming, D Soliman, LC Matemisz, O Niazi, Y Lang, AL Gloyn, ... Diabetes 58 (10), 2419-2424, 2009 | 137 | 2009 |
| Distinct myoprotective roles of cardiac sarcolemmal and mitochondrial KATP channels during metabolic inhibition and recovery PE Light, HD Kanji, JEM Fox, RJ French The FASEB journal 15 (14), 2586-2594, 2001 | 134 | 2001 |
| Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules JK Kruit, N Wijesekara, JEM Fox, XQ Dai, LR Brunham, GJ Searle, ... Diabetes 60 (12), 3186-3196, 2011 | 132 | 2011 |
| Kir6. 2 polymorphisms sensitize β-cell ATP-sensitive potassium channels to activation by acyl CoAs: a possible cellular mechanism for increased susceptibility to type 2 diabetes? MJ Riedel, P Boora, D Steckley, G de Vries, PE Light Diabetes 52 (10), 2630-2635, 2003 | 119 | 2003 |
| Variations in tissue selectivity amongst insulin secretagogues: a systematic review AS Abdelmoneim, SE Hasenbank, JM Seubert, DR Brocks, PE Light, ... Diabetes, obesity and metabolism 14 (2), 130-138, 2012 | 116 | 2012 |
| Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction PC Kienesberger, T Pulinilkunnil, MMY Sung, J Nagendran, ... Molecular and cellular biology 32 (4), 740-750, 2012 | 115 | 2012 |
| Constitutively Active Adenosine Monophosphate–Activated Protein Kinase Regulates Voltage-Gated Sodium Channels in Ventricular Myocytes PE Light, CHR Wallace, JRB Dyck Circulation 107 (15), 1962-1965, 2003 | 114 | 2003 |
