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Rohan Diwanji
Rohan Diwanji
Biogen, Novartis, Dicerna, Northeastern University
在 novartis.com 的电子邮件经过验证
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TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts
AL Grauel, B Nguyen, D Ruddy, T Laszewski, S Schwartz, J Chang, ...
Nature communications 11 (1), 6315, 2020
1502020
Specific inhibition of hepatic lactate dehydrogenase reduces oxalate production in mouse models of primary hyperoxaluria
C Lai, N Pursell, J Gierut, U Saxena, W Zhou, M Dills, R Diwanji, C Dutta, ...
Molecular Therapy 26 (8), 1983-1995, 2018
1122018
In vivo T Cell Activation in Lymphoid Tissues is Inhibited in the Oxygen-Poor Microenvironment
A Ohta, R Diwanji, R Kini, M Subramanian, A Ohta, M Sitkovsky
Frontiers in immunology 2, 27, 2011
1022011
Inhibition of glycolate oxidase with dicer-substrate siRNA reduces calcium oxalate deposition in a mouse model of primary hyperoxaluria type 1
C Dutta, N Avitahl-Curtis, N Pursell, ML Cohen, B Holmes, R Diwanji, ...
Molecular Therapy 24 (4), 770-778, 2016
952016
Knockdown of β-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo
H Dudek, DH Wong, R Arvan, A Shah, K Wortham, B Ying, R Diwanji, ...
Molecular Therapy 22 (1), 92-101, 2014
712014
Effect of in vivo Hydroxychloroquine and ex vivo Anti-BDCA2 mAb Treatment on pDC IFNα Production From Patients Affected With Cutaneous Lupus Erythematosus
A Gardet, A Pellerin, CA McCarl, R Diwanji, W Wang, D Donaldson, ...
Frontiers in immunology 10, 275, 2019
422019
Inhibition of glycogen synthase II with RNAi prevents liver injury in mouse models of glycogen storage diseases
N Pursell, J Gierut, W Zhou, M Dills, R Diwanji, M Gjorgjieva, U Saxena, ...
Molecular Therapy 26 (7), 1771-1782, 2018
342018
Targeting the IL1β pathway for cancer immunotherapy remodels the tumor microenvironment and enhances antitumor immune responses
R Diwanji, NA O'Brien, JE Choi, B Nguyen, T Laszewski, AL Grauel, Z Yan, ...
Cancer Immunology Research 11 (6), 777-791, 2023
182023
Targeting the IL-1beta pathway for cancer immunotherapy remodels the tumor microenvironment and enhances antitumor immune responses. Cancer Immunol Res. 2023
R Diwanji, NA O’Brien, JE Choi
6
Abstract C103: Targeting IL-1β pathway for cancer immunotherapy
P Jayaraman, J Millholland, N O’Brien, C Wong, R Diwanji, M Wang, ...
Molecular Cancer Therapeutics 18 (12_Supplement), C103-C103, 2019
52019
Abstract B20: EnCore-LNP mediated tumor delivery of MYC and CTNNB1 Dicer Substrate RNAs (DsiRNAs)
M Abrams, S Ganesh, B Ying, G Chopda, U Saxena, A Shah, M Koser, ...
Molecular Cancer Therapeutics 13 (10_Supplement), B20-B20, 2015
52015
Targeting tumor-promoting inflammation (TPI) via the IL-1βpathway for cancer immunotherapy
P Jayaraman, V Rodrik-Outmezguine, J Millholland, N O'Brien, C Wong, ...
Cancer Research 80 (16_Supplement), 5640-5640, 2020
42020
Anti IL-1b as a cancer immunotherapy.
R Singh, R Diwanji, P Jayaraman, D Chiang, C Sabatos-Peyton, ...
CANCER IMMUNOLOGY RESEARCH 8 (4), 73-73, 2020
22020
Abstract B222: Dicer substrate siRNAs to MYC, B-catenin, and other target genes effectively induce in vivo target gene knockdown and tumor inhibition.
H Dudek, K Wortham, R Arvan, A Shah, B Ying, W Cyr, H Yang, W Zhou, ...
Molecular Cancer Therapeutics 12 (11_Supplement), B222-B222, 2013
12013
Dicer substrate siRNAs to MYC, B-catenin, and other target genes effectively induce in vivo target gene knockdown and tumor inhibition.
H Dudek, K Wortham, R Aryan, A Shah, B Ying, W Cyr, H Yang, W Zhou, ...
MOLECULAR CANCER THERAPEUTICS 12 (11), 2013
12013
Abstract A76: Anti IL-1b as a cancer immunotherapy
R Singh, R Diwanji, P Jayaraman, D Chiang, C Sabatos-Peyton, ...
Cancer Immunology Research 8 (4_Supplement), A76-A76, 2020
2020
AB0043 EFFECT OF IN VIVO HYDROXYCHLOROQUINE AND EX VIVO ANTI-BDCA2 TREATMENT ON PDC IFNα PRODUCTION FROM PATIENTS AFFECTED WITH CUTANEOUS LUPUS ERYTHEMATOSUS
A Gardet, A Pellerin, CA Mccarl, R Diwanji, W Wang, D Donaldson, ...
Annals of the Rheumatic Diseases 78 (Suppl 2), 1488-1488, 2019
2019
Evaluation of Glyoxylate and Hydroxyproline Metabolic Pathways Through the Use of Dicer-Substrate Small Interfering RNA
N Avitahl-Curtis, B Holmes, L Apponi, R Diwanji, MSL Cohen, C Dutta, ...
HEPATOLOGY 62, 464A-464A, 2015
2015
Dicer-Substrate Small RNAs as Potential Therapeutics for Hepatic Diseases
NW Pursell, R Diwanji, UH Saxena, H Dudek, N Avitahl-Curtis, C Dutta, ...
HEPATOLOGY 62, 1238A-1239A, 2015
2015
358 Knockdown of beta-catenin with dicer-substrate siRNAs down-regulates Wnt/beta-catenin pathway signaling
N Pursell, W Zhou, R Diwanji, B Holmes, N Avitahl-Curtis, C Dutta, ...
European Journal of Cancer, 115-116, 2014
2014
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