Restoration of replication fork stability in BRCA1-and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers A Taglialatela, S Alvarez, G Leuzzi, V Sannino, L Ranjha, JW Huang, ... Molecular cell 68 (2), 414-430. e8, 2017 | 369 | 2017 |
Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity M Vujanovic, J Krietsch, MC Raso, N Terraneo, R Zellweger, JA Schmid, ... Molecular cell 67 (5), 882-890. e5, 2017 | 244 | 2017 |
Functional interrogation of DNA damage response variants with base editing screens R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ... Cell 184 (4), 1081-1097. e19, 2021 | 183 | 2021 |
MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression Y Wang, JW Huang, M Li, WK Cavenee, PS Mitchell, X Zhou, M Tewari, ... Molecular Cancer Research 9 (8), 1100-1111, 2011 | 169 | 2011 |
MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition Y Wang, JW Huang, P Calses, CJ Kemp, T Taniguchi Cancer research 72 (16), 4037-4046, 2012 | 144 | 2012 |
Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant TS Nambiar, P Billon, G Diedenhofen, SB Hayward, A Taglialatela, K Cai, ... Nature Communications 10 (1), 3395, 2019 | 127 | 2019 |
REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps A Taglialatela, G Leuzzi, V Sannino, R Cuella-Martin, JW Huang, ... Molecular cell 81 (19), 4008-4025. e7, 2021 | 122 | 2021 |
Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response A Ciccia, JW Huang, L Izhar, ME Sowa, JW Harper, SJ Elledge Proceedings of the National Academy of Sciences 111 (52), 18631-18636, 2014 | 114 | 2014 |
Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity JW Huang, Y Wang, KK Dhillon, P Calses, E Villegas, PS Mitchell, ... Molecular cancer research 11 (12), 1564-1573, 2013 | 112 | 2013 |
FANCI regulates recruitment of the FA core complex at sites of DNA damage independently of FANCD2 M Castella, C Jacquemont, EL Thompson, JE Yeo, RS Cheung, ... PLoS genetics 11 (10), e1005563, 2015 | 93 | 2015 |
p53 is positively regulated by miR-542-3p Y Wang, JW Huang, M Castella, DG Huntsman, T Taniguchi Cancer research 74 (12), 3218-3227, 2014 | 68 | 2014 |
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage JW Huang, A Acharya, A Taglialatela, TS Nambiar, R Cuella-Martin, ... Nature communications 11 (1), 2948, 2020 | 39 | 2020 |
DGCR8 mediates repair of UV-induced DNA damage independently of RNA processing PC Calses, KK Dhillon, N Tucker, Y Chi, J Huang, M Kawasumi, ... Cell reports 19 (1), 162-174, 2017 | 39 | 2017 |
Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease SA Joseph, A Taglialatela, G Leuzzi, JW Huang, R Cuella-Martin, A Ciccia DNA repair 95, 102943, 2020 | 29 | 2020 |
The synthesis and proteasomal degradation of a model substrate Ub5DHFR YA Lam, JW Huang, O Showole Methods in enzymology 398, 379-390, 2005 | 14 | 2005 |
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion G Leuzzi, A Vasciaveo, A Taglialatela, X Chen, TM Firestone, ... Cell 187 (4), 861-881. e32, 2024 | 9 | 2024 |
Mechanism of DNA unwinding by MCM8-9 in complex with HROB A Acharya, H Bret, JW Huang, M Mütze, M Göse, VM Kissling, R Seidel, ... Nature Communications 15 (1), 3584, 2024 | 1 | 2024 |
Mechanism of DNA unwinding by hexameric MCM8–9 in complex with HROB A Acharya, H Bret, JW Huang, M Mütze, M Göse, V Kissling, R Seidel, ... Research Square, 2023 | 1 | 2023 |
MicroRNA-103 and 107 target RAD51 and RAD51D to regulate homologous recombination and enhance cellular sensitivity to DNA damaging agents JW Huang | 1 | 2013 |
MicroRNA-mediated regulation of the Fanconi anemia-BRCA pathway JW Huang, E Villegas, T Taniguchi Cancer Research 70 (8_Supplement), 1951-1951, 2010 | 1 | 2010 |