| Preparation of selenoinsulin as a long‐lasting insulin analogue K Arai, T Takei, M Okumura, S Watanabe, Y Amagai, Y Asahina, ... Angewandte Chemie 129 (20), 5614-5618, 2017 | 98 | 2017 |
| Difluoro‐and Trifluoromethylation of Electron‐Deficient Alkenes in an Electrochemical Microreactor K Arai, K Watts, T Wirth ChemistryOpen 3 (1), 23-28, 2014 | 88 | 2014 |
| Antioxidative glutathione peroxidase activity of selenoglutathione S Yoshida, F Kumakura, I Komatsu, K Arai, Y Onuma, H Hojo, BG Singh, ... Angewandte Chemie 123 (9), 2173-2176, 2011 | 74 | 2011 |
| From sulfur to selenium. A new research arena in chemical biology and biological chemistry M Iwaoka, K Arai Current Chemical Biology 7 (1), 2-24, 2013 | 66 | 2013 |
| Effects of ring size and polar functional groups on the glutathione peroxidase-like antioxidant activity of water-soluble cyclic selenides K Arai, F Kumakura, M Takahira, N Sekiyama, N Kuroda, T Suzuki, ... The Journal of Organic Chemistry 80 (11), 5633-5642, 2015 | 49 | 2015 |
| Selenoglutathione diselenide: unique redox reactions in the GPx-like catalytic cycle and repairing of disulfide bonds in scrambled protein S Shimodaira, Y Asano, K Arai, M Iwaoka Biochemistry 56 (42), 5644-5653, 2017 | 48 | 2017 |
| Rapid and quantitative disulfide bond formation for a polypeptide chain using a cyclic selenoxide reagent in an aqueous medium K Arai, K Dedachi, M Iwaoka Chemistry–A European Journal 17 (2), 481-485, 2011 | 44 | 2011 |
| Rapid electrochemical deprotection of the isonicotinyloxycarbonyl group from carbonates and thiocarbonates in a microfluidic reactor K Arai, T Wirth Organic Process Research & Development 18 (11), 1377-1381, 2014 | 38 | 2014 |
| Protein Folding in the Presence of Water‐Soluble Cyclic Diselenides with Novel Oxidoreductase and Isomerase Activities K Arai, H Ueno, Y Asano, G Chakrabarty, S Shimodaira, G Mugesh, ... ChemBioChem 19 (3), 207-211, 2018 | 37 | 2018 |
| Modeling Thioredoxin Reductase‐Like Activity with Cyclic Selenenyl Sulfides: Participation of an NH⋅⋅⋅ Se Hydrogen Bond through Stabilization of the Mixed Se− S Intermediate K Arai, T Matsunaga, H Ueno, N Akahoshi, Y Sato, G Chakrabarty, ... Chemistry–A European Journal 25 (55), 12751-12760, 2019 | 35 | 2019 |
| Characterization and optimization of two-chain folding pathways of insulin via native chain assembly K Arai, T Takei, R Shinozaki, M Noguchi, S Fujisawa, H Katayama, ... Communications Chemistry 1 (1), 26, 2018 | 30 | 2018 |
| Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding S Okada, M Matsusaki, K Arai, Y Hidaka, K Inaba, M Okumura, T Muraoka Chemical communications 55 (6), 759-762, 2019 | 29 | 2019 |
| Model study using designed selenopeptides on the importance of the catalytic triad for the antioxidative functions of glutathione peroxidase T Takei, Y Urabe, Y Asahina, H Hojo, T Nomura, K Dedachi, K Arai, ... The Journal of Physical Chemistry B 118 (2), 492-500, 2014 | 29 | 2014 |
| Glutathione peroxidase-like functions of 1, 2-diselenane-4, 5-diol and its amphiphilic derivatives: Switchable catalytic cycles depending on peroxide substrates K Arai, Y Sato, I Nakajima, M Saito, M Sasaki, A Kanamori, M Iwaoka Bioorganic & Medicinal Chemistry 29, 115866, 2021 | 27 | 2021 |
| Glutathione peroxidase-like activity of amino-substituted water-soluble cyclic selenides: A shift of the major catalytic cycle in methanol K Arai, A Tashiro, Y Osaka, M Iwaoka Molecules 22 (3), 354, 2017 | 27 | 2017 |
| An amphiphilic selenide catalyst behaves like a hybrid mimic of protein disulfide isomerase and glutathione peroxidase 7 K Arai, K Moriai, A Ogawa, M Iwaoka Chemistry–An Asian Journal 9 (12), 3464-3471, 2014 | 23 | 2014 |
| Fatty Acid Conjugates of Water‐Soluble (±)‐trans‐Selenolane‐3,4‐diol: Effects of Alkyl Chain Length on the Antioxidant Capacity M Iwaoka, N Sano, YY Lin, A Katakura, M Noguchi, K Takahashi, ... ChemBioChem 16 (8), 1226-1234, 2015 | 21 | 2015 |
| Flexible folding: Disulfide-containing peptides and proteins choose the pathway depending on the environments K Arai, M Iwaoka Molecules 26 (1), 195, 2021 | 20 | 2021 |
| Basic Amino Acid Conjugates of 1, 2‐Diselenan‐4‐amine with Protein Disulfide Isomerase‐like Functions as a Manipulator of Protein Quality Control S Tsukagoshi, R Mikami, K Arai Chemistry–An Asian Journal 15 (17), 2646-2652, 2020 | 20 | 2020 |
| A water-soluble selenoxide reagent as a useful probe for the reactivity and folding of polythiol peptides K Arai, M Noguchi, BG Singh, KI Priyadarsini, K Fujio, Y Kubo, ... FEBS Open Bio 3, 55-64, 2013 | 20 | 2013 |
