In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity SM Bryce, JC Bemis, SL Avlasevich, SD Dertinger Mutation Research/Genetic Toxicology and Environmental Mutagenesis 630 (1-2 …, 2007 | 248 | 2007 |
Polychlorinated biphenyls and methylmercury act synergistically to reduce rat brain dopamine content in vitro. JC Bemis, RF Seegal Environmental health perspectives 107 (11), 879-885, 1999 | 188 | 1999 |
In vivo mutation assay based on the endogenous Pig‐a locus SM Bryce, JC Bemis, SD Dertinger Environmental and molecular mutagenesis 49 (4), 256-264, 2008 | 157 | 2008 |
A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo EC Henry, JC Bemis, O Henry, AS Kende, TA Gasiewicz Archives of biochemistry and biophysics 450 (1), 67-77, 2006 | 134 | 2006 |
Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay SM Bryce, SL Avlasevich, JC Bemis, M Lukamowicz, A Elhajouji, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 650 (2 …, 2008 | 114 | 2008 |
PCB-induced inhibition of the vesicular monoamine transporter predicts reductions in synaptosomal dopamine content JC Bemis, RF Seegal Toxicological Sciences 80 (2), 288-295, 2004 | 114 | 2004 |
Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies SD Dertinger, S Phonethepswath, D Franklin, P Weller, DK Torous, ... Toxicological Sciences 115 (2), 401-411, 2010 | 108 | 2010 |
Erythrocyte-based Pig-a gene mutation assay: Demonstration of cross-species potential S Phonethepswath, SM Bryce, JC Bemis, SD Dertinger Mutation Research/Genetic Toxicology and Environmental Mutagenesis 657 (2 …, 2008 | 105 | 2008 |
Efficient Monitoring of In Vivo Pig-a Gene Mutation and Chromosomal Damage: Summary of 7 Published Studies and Results From 11 New Reference Compounds SD Dertinger, S Phonethepswath, SL Avlasevich, DK Torous, J Mereness, ... Toxicological sciences 130 (2), 328-348, 2012 | 104 | 2012 |
Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens S Phonethepswath, D Franklin, DK Torous, SM Bryce, JC Bemis, S Raja, ... Toxicological sciences 114 (1), 59-70, 2010 | 104 | 2010 |
Polychlorinated biphenyls alter extraneuronal but not tissue dopamine concentrations in adult rat striatum: an in vivo microdialysis study. RF Seegal, RJ Okoniewski, KO Brosch, JC Bemis Environmental Health Perspectives 110 (11), 1113-1117, 2002 | 96 | 2002 |
Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach SM Bryce, DT Bernacki, JC Bemis, SD Dertinger Environmental and Molecular Mutagenesis 57 (3), 171-189, 2016 | 83 | 2016 |
Polychlorinated biphenyls and methylmercury alter intracellular calcium concentrations in rat cerebellar granule cells. JC Bemis, RF Seegal Neurotoxicology 21 (6), 1123-1134, 2000 | 83 | 2000 |
Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations KL Dearfield, BB Gollapudi, JC Bemis, RD Benz, GR Douglas, ... Environmental and Molecular Mutagenesis 58 (5), 264-283, 2017 | 74 | 2017 |
EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress SA Peslak, J Wenger, JC Bemis, PD Kingsley, AD Koniski, KE McGrath, ... Blood, The Journal of the American Society of Hematology 120 (12), 2501-2511, 2012 | 73 | 2012 |
High content flow cytometric micronucleus scoring method is applicable to attachment cell lines SM Bryce, J Shi, J Nicolette, M Diehl, P Sonders, S Avlasevich, S Raja, ... Environmental and molecular mutagenesis 51 (3), 260-266, 2010 | 70 | 2010 |
Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay SM Bryce, DT Bernacki, JC Bemis, RA Spellman, ME Engel, M Schuler, ... Environmental and Molecular Mutagenesis 58 (3), 146-161, 2017 | 69 | 2017 |
Investigating the generalizability of the MultiFlow® DNA damage assay and several companion machine learning models with a set of 103 diverse test chemicals SM Bryce, DT Bernacki, SL Smith-Roe, KL Witt, JC Bemis, SD Dertinger Toxicological Sciences 162 (1), 146-166, 2018 | 59 | 2018 |
Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents SM Bryce, JC Bemis, JA Mereness, RA Spellman, J Moss, D Dickinson, ... Environmental and Molecular Mutagenesis 55 (7), 542-555, 2014 | 59 | 2014 |
Sublethal radiation injury uncovers a functional transition during erythroid maturation SA Peslak, J Wenger, JC Bemis, PD Kingsley, JM Frame, AD Koniski, ... Experimental hematology 39 (4), 434-445, 2011 | 57 | 2011 |