A gene-based association method for mapping traits using reference transcriptome data ER *Gamazon, HE *Wheeler, KP *Shah, SV Mozaffari, K Aquino-Michaels, ... Nature genetics 47 (9), 1091, 2015 | 1625 | 2015 |
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics AN Barbeira, SP Dickinson, R Bonazzola, J Zheng, HE Wheeler, ... Nature communications 9 (1), 1825, 2018 | 888 | 2018 |
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia B Diouf, KR Crews, G Lew, D Pei, C Cheng, J Bao, JJ Zheng, W Yang, ... Jama 313 (8), 815-823, 2015 | 294 | 2015 |
Integrating predicted transcriptome from multiple tissues improves association detection AN Barbeira, M Pividori, J Zheng, HE Wheeler, DL Nicolae, HK Im PLoS genetics 15 (1), e1007889, 2019 | 293 | 2019 |
Comprehensive audiometric analysis of hearing impairment and tinnitus after cisplatin-based chemotherapy in survivors of adult-onset cancer RD *Frisina, HE *Wheeler, SD Fossa, SL Kerns, C Fung, HD Sesso, ... Journal of Clinical Oncology 34 (23), 2712, 2016 | 268 | 2016 |
Cancer pharmacogenomics: strategies and challenges HE Wheeler, ML Maitland, ME Dolan, NJ Cox, MJ Ratain Nature Reviews Genetics 14 (1), 23-34, 2013 | 251 | 2013 |
Genome-wide association and functional follow-up reveals new loci for kidney function C Pattaro, A Köttgen, A Teumer, M Garnaas, CA Böger, C Fuchsberger, ... PLoS genetics 8 (3), e1002584, 2012 | 214 | 2012 |
Survey of the heritability and sparse architecture of gene expression traits across human tissues HE Wheeler, KP Shah, J Brenner, T Garcia, K Aquino-Michaels, ... PLoS genetics 12 (11), e1006423, 2016 | 168 | 2016 |
Genetic architecture of gene expression traits across diverse populations LS Mogil, A Andaleon, A Badalamenti, SP Dickinson, X Guo, JI Rotter, ... PLoS genetics 14 (8), e1007586, 2018 | 148 | 2018 |
Genetics and genomics of human ageing HE Wheeler, SK Kim Philosophical Transactions of the Royal Society B: Biological Sciences 366 …, 2011 | 143 | 2011 |
Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation HE Wheeler, ME Dolan Pharmacogenomics 13 (1), 55-70, 2012 | 130 | 2012 |
Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells HE Wheeler, C Wing, SM Delaney, M Komatsu, ME Dolan PloS one 10 (2), e0118020, 2015 | 109 | 2015 |
Relating human genetic variation to variation in drug responses AG Madian, HE Wheeler, RB Jones, ME Dolan Trends in genetics 28 (10), 487-495, 2012 | 109 | 2012 |
Genetic regulatory variation in populations informs transcriptome analysis in rare disease P Mohammadi, SE Castel, BB Cummings, J Einson, C Sousa, P Hoffman, ... Science 366 (6463), 351-356, 2019 | 97 | 2019 |
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function AB Wyss, T Sofer, MK Lee, N Terzikhan, JN Nguyen, L Lahousse, ... Nature communications 9 (1), 2976, 2018 | 97 | 2018 |
Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging HE Wheeler, EJ Metter, T Tanaka, D Absher, J Higgins, JM Zahn, ... PLoS Genetics 5 (10), e1000685, 2009 | 89 | 2009 |
Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity HE Wheeler, ER Gamazon, RD Frisina, C Perez-Cervantes, O El Charif, ... Clinical Cancer Research 23 (13), 3325-3333, 2017 | 83 | 2017 |
Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy LJ Leandro-García, S Leskelä, C Jara, H Gréen, E Åvall-Lundqvist, ... Clinical Cancer Research 18 (16), 4441-4448, 2012 | 79 | 2012 |
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function DI Chasman, C Fuchsberger, C Pattaro, A Teumer, CA Böger, K Endlich, ... Human molecular genetics 21 (24), 5329-5343, 2012 | 78 | 2012 |
Clinical and genome-wide analysis of cisplatin-induced peripheral neuropathy in survivors of adult-onset cancer ME Dolan, O El Charif, HE Wheeler, ER Gamazon, ... Clinical Cancer Research 23 (19), 5757-5768, 2017 | 77 | 2017 |