Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease. E Ito, K Oka, R Etcheberrigaray, TJ Nelson, DL McPhie, B Tofel-Grehl, ... Proceedings of the National Academy of Sciences 91 (2), 534-538, 1994 | 425 | 1994 |
Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus JL Olds, ML Anderson, DL McPhie, LD Staten, DL Alkon Science 245 (4920), 866-869, 1989 | 314 | 1989 |
Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein ML Oster-Granite, DL McPhie, J Greenan, RL Neve Journal of Neuroscience 16 (21), 6732-6741, 1996 | 274 | 1996 |
Abnormalities in mitochondrial structure in cells from patients with bipolar disorder AM Cataldo, DL McPhie, NT Lange, S Punzell, S Elmiligy, ZY Nancy, ... The American journal of pathology 177 (2), 575-585, 2010 | 270 | 2010 |
Alzheimer’s disease: a dysfunction of the amyloid precursor protein RL Neve, DL McPhie, Y Chen Brain research 886 (1-2), 54-66, 2000 | 196 | 2000 |
Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons T Yoshimizu, JQ Pan, AE Mungenast, JM Madison, S Su, J Ketterman, ... Molecular psychiatry 20 (2), 162-169, 2015 | 176 | 2015 |
The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the SM checkpoint and causes apoptosis in neurons Y Chen, DL McPhie, J Hirschberg, RL Neve Journal of Biological Chemistry 275 (12), 8929-8935, 2000 | 170 | 2000 |
DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3 DL McPhie, R Coopersmith, A Hines-Peralta, Y Chen, KJ Ivins, SP Manly, ... Journal of Neuroscience 23 (17), 6914-6927, 2003 | 167 | 2003 |
Late-onset Alzheimer’s disease is associated with inherent changes in bioenergetics profiles KC Sonntag, WI Ryu, KM Amirault, RA Healy, AJ Siegel, DL McPhie, ... Scientific reports 7 (1), 1-13, 2017 | 130 | 2017 |
Genetic and clinical factors predict lithium’s effects on PER2 gene expression rhythms in cells from bipolar disorder patients MJ McCarthy, H Wei, Z Marnoy, RM Darvish, DL McPhie, BM Cohen, ... Translational psychiatry 3 (10), e318-e318, 2013 | 130 | 2013 |
Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis S Bursztajn, R DeSouza, DL McPhie, SA Berman, J Shioi, NK Robakis, ... Journal of Neuroscience 18 (23), 9790-9799, 1998 | 130 | 1998 |
Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats JL Olds, S Golski, DL McPhie, D Olton, M Mishkin, DL Alkon Journal of Neuroscience 10 (11), 3707-3713, 1990 | 130 | 1990 |
The cell cycle as a therapeutic target for Alzheimer's disease RL Neve, DL McPhie Pharmacology & therapeutics 111 (1), 99-113, 2006 | 123 | 2006 |
Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell–Derived Cerebral Organoids in Schizophrenia A Kathuria, K Lopez-Lengowski, SS Jagtap, D McPhie, RH Perlis, ... JAMA psychiatry, 2020 | 121 | 2020 |
Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein J Berger-Sweeney, DL McPhie, JA Arters, J Greenan, ML Oster-Granite, ... Molecular brain research 66 (1-2), 150-162, 1999 | 115 | 1999 |
The neuronal growth-associated protein GAP-43 interacts with rabaptin-5 and participates in endocytosis RL Neve, R Coopersmith, DL McPhie, C Santeufemio, KG Pratt, ... Journal of Neuroscience 18 (19), 7757-7767, 1998 | 111 | 1998 |
Isolated mitochondria transfer improves neuronal differentiation of schizophrenia-derived induced pluripotent stem cells and rescues deficits in a rat model of the disorder O Robicsek, HM Ene, R Karry, O Ytzhaki, E Asor, D McPhie, BM Cohen, ... Schizophrenia bulletin 44 (2), 432-442, 2018 | 103 | 2018 |
APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain Y Chen, W Liu, DL McPhie, L Hassinger, RL Neve The Journal of cell biology 163 (1), 27-33, 2003 | 103 | 2003 |
Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell–derived cortical interneurons from subjects with schizophrenia Z Shao, H Noh, WB Kim, P Ni, C Nguyen, SE Cote, E Noyes, J Zhao, ... Nature neuroscience 22 (2), 229-242, 2019 | 98 | 2019 |
Aβ42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3β signaling-dependent mechanism T Suhara, J Magrané, K Rosen, R Christensen, HS Kim, B Zheng, ... Neurobiology of aging 24 (3), 437-451, 2003 | 96 | 2003 |