Bicyclic nucleosides, oligonucleotides, process for their preparation and intermediates C Leumann US Patent 5,319,080, 1994 | 687 | 1994 |
Bicyclic nucleosides, oligonucleotides, process for their preparation and intermediates C Leumann US Patent 5,393,878, 1995 | 684 | 1995 |
DNA analogues: from supramolecular principles to biological properties CJ Leumann Bioorganic & medicinal chemistry 10 (4), 841-854, 2002 | 382 | 2002 |
Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers A Goyenvalle, G Griffith, A Babbs, SE Andaloussi, K Ezzat, A Avril, ... Nature medicine 21 (3), 270-275, 2015 | 318 | 2015 |
A new strategy for the generation of catalytic antibodies KM Shokat, CJ Leumann, R Sugasawara, PG Schultz Nature 338 (6212), 269-271, 1989 | 259 | 1989 |
Recent improvements in antigene technology S Buchini, CJ Leumann Current opinion in chemical biology 7 (6), 717-726, 2003 | 209 | 2003 |
Nucleic‐Acid Analogues with Constraint Conformational Flexibility in the Sugar‐Phosphate Backbone (‘Bicyclo‐DNA’). Part 1. Preparation of (3S, 5′ R)‐2′‐Deoxy‐3′, 5′‐ethano … M Tarköy, M Bolli, B Schweizer, C Leumann Helvetica chimica acta 76 (1), 481-510, 1993 | 188 | 1993 |
Watson− crick base-pairing properties of tricyclo-DNA D Renneberg, CJ Leumann Journal of the American Chemical Society 124 (21), 5993-6002, 2002 | 179 | 2002 |
Synthesis and thermodynamic and biophysical properties of tricyclo-DNA R Steffens, CJ Leumann Journal of the American Chemical Society 121 (14), 3249-3255, 1999 | 154 | 1999 |
5-Substituted 2-aminopyridine C-nucleosides as protonated cytidine equivalents: increasing efficiency and selectivity in DNA triple-helix formation S Hildbrand, A Blaser, SP Parel, CJ Leumann Journal of the American Chemical Society 119 (24), 5499-5511, 1997 | 152 | 1997 |
Bipyridyl‐and biphenyl‐DNA: A recognition motif based on interstrand aromatic stacking C Brotschi, G Mathis, CJ Leumann Chemistry–A European Journal 11 (6), 1911-1923, 2005 | 151 | 2005 |
Why Pentose‐and Not Hexose‐Nucleic Acids? Purine‐Purine Pairing in homo‐DNA: Guanine, Isoguanine, 2, 6‐Diaminopurine, and Xanthine. K Groebke, J Hunziker, W Fraser, L Peng, U Diederichsen, ... ChemInform 29 (23), no-no, 1998 | 142 | 1998 |
Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center J Willi, P Küpfer, D Evéquoz, G Fernandez, A Katz, C Leumann, ... Nucleic acids research 46 (4), 1945-1957, 2018 | 141 | 2018 |
Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system M Egli, PS Pallan, R Pattanayek, CJ Wilds, P Lubini, G Minasov, M Dobler, ... Journal of the American Chemical Society 128 (33), 10847-10856, 2006 | 140 | 2006 |
A stable DNA duplex containing a non-hydrogen-bonding and non-shape-complementary base couple: interstrand stacking as the stability determining factor. C Brotschi, A Häberli, CJ Leumann Angewandte Chemie (International ed. in English) 40 (16), 3012-3014, 2001 | 139 | 2001 |
Antisense properties of tricyclo-DNA D Renneberg, E Bouliong, U Reber, D Schümperli, CJ Leumann Nucleic acids research 30 (13), 2751-2757, 2002 | 124 | 2002 |
Tricyclo-DNA: a phosphodiester-backbone based DNA analog exhibiting strong complementary base-pairing properties R Steffens, CJ Leumann Journal of the American Chemical Society 119 (47), 11548-11549, 1997 | 122 | 1997 |
Pentafluorophenyl–Phenyl Interactions in Biphenyl‐DNA A Zahn, C Brotschi, CJ Leumann Chemistry–A European Journal 11 (7), 2125-2129, 2005 | 119 | 2005 |
Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides K Ezzat, Y Aoki, T Koo, G McClorey, L Benner, A Coenen-Stass, ... Nano letters 15 (7), 4364-4373, 2015 | 114 | 2015 |
Nucleic‐Acid Analogues with Restricted Conformational Flexibility in the Sugar‐Phosphate Backbone (‘bicyclo‐DNA’). Part 3. Synthesis, pairing properties, and calorimetric … M Tarköy, M Bolli, C Leumann Helvetica chimica acta 77 (3), 716-744, 1994 | 103 | 1994 |