The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins LS Harrington, GM Findlay, A Gray, T Tolkacheva, S Wigfield, H Rebholz, ... The Journal of cell biology 166 (2), 213-223, 2004 | 1372 | 2004 |
Restraining PI3K: mTOR signalling goes back to the membrane LS Harrington, GM Findlay, RF Lamb Trends in biochemical sciences 30 (1), 35-42, 2005 | 467 | 2005 |
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling GM Findlay, L Yan, J Procter, V Mieulet, RF Lamb Biochemical Journal 403 (1), 13-20, 2007 | 326 | 2007 |
PP2AT61ɛ is an inhibitor of MAP4K3 in nutrient signaling to mTOR L Yan, V Mieulet, D Burgess, GM Findlay, K Sully, J Procter, J Goris, ... Molecular cell 37 (5), 633-642, 2010 | 146 | 2010 |
A quantitative liposome microarray to systematically characterize protein-lipid interactions AE Saliba, I Vonkova, S Ceschia, GM Findlay, K Maeda, C Tischer, ... nature methods 11 (1), 47-50, 2014 | 91 | 2014 |
Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase L Yan, GM Findlay, R Jones, J Procter, Y Cao, RF Lamb Journal of Biological Chemistry 281 (29), 19793-19797, 2006 | 78 | 2006 |
Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate GM Findlay, MJ Smith, F Lanner, MS Hsiung, GD Gish, E Petsalaki, ... Cell 152 (5), 1008-1020, 2013 | 68 | 2013 |
TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation? GM Findlay, LS Harrington, RF Lamb Current opinion in genetics & development 15 (1), 69-76, 2005 | 52 | 2005 |
Erk5 is a key regulator of naive-primed transition and embryonic stem cell identity CAC Williams, R Fernandez-Alonso, J Wang, R Toth, NS Gray, ... Cell Reports 16 (7), 1820-1828, 2016 | 51 | 2016 |
Functional diversification of SRSF protein kinase to control ubiquitin-dependent neurodevelopmental signaling F Bustos, A Segarra-Fas, G Nardocci, A Cassidy, O Antico, L Davidson, ... Developmental cell 55 (5), 629-647. e7, 2020 | 41 | 2020 |
Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation N Yasui, GM Findlay, GD Gish, MS Hsiung, J Huang, M Tucholska, ... Molecular cell 54 (6), 1034-1041, 2014 | 41 | 2014 |
RNF12 X-linked intellectual disability mutations disrupt E3 ligase activity and neural differentiation F Bustos, A Segarra-Fas, VK Chaugule, L Brandenburg, E Branigan, ... Cell reports 23 (6), 1599-1611, 2018 | 38 | 2018 |
Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification R Fernandez‐Alonso, L Davidson, J Hukelmann, M Zengerle, AR Prescott, ... EMBO reports 18 (7), 1108-1122, 2017 | 32 | 2017 |
LAR receptor tyrosine phosphatase family in healthy and diseased brain F Cornejo, BI Cortés, GM Findlay, GI Cancino Frontiers in Cell and Developmental Biology 9, 659951, 2021 | 24 | 2021 |
How is SOS activated? Let us count the ways GM Findlay, T Pawson Nature structural & molecular biology 15 (6), 538-540, 2008 | 22 | 2008 |
Protein kinases in pluripotency—beyond the usual suspects R Fernandez-Alonso, F Bustos, CAC Williams, GM Findlay Journal of Molecular Biology 429 (10), 1504-1520, 2017 | 20 | 2017 |
Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation R Fernandez-Alonso, F Bustos, M Budzyk, P Kumar, AO Helbig, ... Nature communications 11 (1), 1357, 2020 | 16 | 2020 |
Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: development of a reproducible and robust sample preparation workflow RE Heap, A Segarra-Fas, AP Blain, GM Findlay, M Trost Analyst 144 (21), 6371-6381, 2019 | 15 | 2019 |
Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self‐renewal NP Mullin, J Varghese, D Colby, JM Richardson, GM Findlay, I Chambers FEBS letters 595 (1), 14-25, 2021 | 10 | 2021 |
A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne–Kalscheuer syndrome F Bustos, C Espejo-Serrano, A Segarra-Fas, R Toth, AJ Eaton, ... Scientific reports 11 (1), 9560, 2021 | 8 | 2021 |