Inhibition of p53 inhibitors: progress, challenges and perspectives G Sanz, M Singh, S Peuget, G Selivanova Journal of molecular cell biology 11 (7), 586-599, 2019 | 135 | 2019 |
MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4 A Lang, S Grether-Beck, M Singh, F Kuck, S Jakob, A Kefalas, ... Aging (Albany NY) 8 (3), 484, 2016 | 129 | 2016 |
Pharmacological activation of p53 triggers viral mimicry response thereby abolishing tumor immune evasion and promoting anti-tumor immunity X Zhou, M Singh, GS Santos, V Guerlavais, LA Carvajal, M Aivado, ... Cancer Discovery, 2021 | 101 | 2021 |
Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes J Zhu, M Singh, G Selivanova, S Peuget Scientific reports 10 (1), 1049, 2020 | 53 | 2020 |
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner HC Thakur, M Singh, L Nagel-Steger, J Kremer, D Prumbaum, EK Fansa, ... Journal of Biological Chemistry 289 (1), 74-88, 2014 | 51 | 2014 |
Adaptive RSK‐EphA2‐GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer L Moyano‐Galceran, EA Pietilä, SP Turunen, S Corvigno, E Hjerpe, ... EMBO molecular medicine 12 (4), e11177, 2020 | 50 | 2020 |
Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice V Devanathan, I Hagedorn, D Köhler, K Pexa, D Cherpokova, P Kraft, ... Proceedings of the National Academy of Sciences 112 (20), 6491-6496, 2015 | 50 | 2015 |
Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division HC Thakur, M Singh, L Nagel-Steger, D Prumbaum, EK Fansa, L Gremer, ... Biological chemistry 394 (11), 1411-1423, 2013 | 35 | 2013 |
Senescence-associated lysosomal α-L-fucosidase (SA-α-Fuc): a sensitive and more robust biomarker for cellular senescence beyond SA-β-Gal M Singh, RP Piekorz Cell cycle 12 (13), 1996-1996, 2013 | 32 | 2013 |
The centrosome and mitotic spindle apparatus in cancer and senescence S Schmidt, F Essmann, IC Cirstea, F Kuck, HC Thakur, M Singh, A Kletke, ... Cell Cycle 9 (22), 4469-4473, 2010 | 28 | 2010 |
Pharmacological activation of p53 triggers viral mimicry response thereby abolishing tumor immune evasion and promoting anti-tumor immunity. Cancer Discov. 2021 doi: 10.1158 … X Zhou, M Singh, G Sanz Santos, V Guerlavais, LA Carvajal, M Aivado, ... CD-20-1741.[Abstract][CrossRef][Google Scholar], 0 | 23 | |
Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds S Peuget, J Zhu, G Sanz, M Singh, M Gaetani, X Chen, Y Shi, AA Saei, ... Cancer Research 80 (7), 1538-1550, 2020 | 18 | 2020 |
MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts F Zhang, SM Zakaria, V Högqvist Tabor, M Singh, S Tronnersjö, ... Cell Cycle 17 (24), 2697-2715, 2018 | 17 | 2018 |
Identification and targeting of selective vulnerability rendered by tamoxifen resistance M Singh, X Zhou, X Chen, GS Santos, S Peuget, Q Cheng, A Rihani, ... Breast Cancer Research 22 (1), 1-16, 2020 | 14 | 2020 |
Class IV Lasso Peptides Synergistically Induce Proliferation of Cancer Cells and Sensitize Them to Doxorubicin JF Guerrero-Garzon, E Madland, M Zehl, M Singh, S Rezaei, ... Iscience 23 (12), 101785, 2020 | 13 | 2020 |
p53 CRISPR Deletion Affects DNA Structure and Nuclear Architecture A Rangel-Pozzo, S Booth, PLI Yu, M Singh, G Selivanova, S Mai Journal of clinical medicine 9 (2), 598, 2020 | 9 | 2020 |
Mutant p53 gain of function mediates cancer immune escape that is counteracted by APR-246 X Zhou, GS Santos, Y Zhan, MMS Oliveira, S Rezaei, M Singh, S Peuget, ... British Journal of Cancer 127 (11), 2060-2071, 2022 | 8 | 2022 |
Gαi3 signaling is associated with sexual dimorphic expression of the clock-controlled output gene Dbp in murine liver M Singh, L Bergmann, A Lang, K Pexa, F Kuck, D Stibane, L Janke, ... Oncotarget 9 (54), 30213, 2018 | 4 | 2018 |
Decreased DNA damage and improved p53 specificity of RITA analogs Y Zhan, X Zhou, S Peuget, M Singh, BD Peyser, Z Fan, G Selivanova Molecular cancer therapeutics, 2022 | 3 | 2022 |
Class IV lasso peptides synergistically induce proliferation of cancer cells and sensitize them to doxorubicin J Felipe Guerrero-Garzón, E Madland, M Zehl, M Singh, S Rezaei, ... Elsevier, 2020 | | 2020 |