The Cell Collective: Toward an open and collaborative approach to systems biology. T Helikar, B Kowal, S McClenathan, M Bruckner, T Rowley, B Wicks, ... BMC Systems Biology 6 (1), 96, 2012 | 259 | 2012 |
Logical modeling and dynamical analysis of cellular networks W Abou-Jaoudé, P Traynard, PT Monteiro, J Saez-Rodriguez, T Helikar, ... Frontiers in genetics 7, 94, 2016 | 235 | 2016 |
Emergent decision-making in biological signal transduction networks T Helikar, J Konvalina, J Heidel, JA Rogers Proceedings of the National Academy of Sciences 105 (6), 1913-1918, 2008 | 231 | 2008 |
SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 211 | 2020 |
SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools C Chaouiya, D Bérenguier, SM Keating, A Naldi, MP Van Iersel, ... BMC systems biology 7, 1-15, 2013 | 189 | 2013 |
The CoLoMoTo interactive notebook: accessible and reproducible computational analyses for qualitative biological networks A Naldi, C Hernandez, N Levy, G Stoll, PT Monteiro, C Chaouiya, ... Frontiers in physiology 9, 680, 2018 | 91 | 2018 |
Cooperative development of logical modelling standards and tools with CoLoMoTo. A Naldi, PT Monteiro, C Müssel, HA Kestler, D Thieffry, I Xenarios, ... Bioinformatics 31 (7), 2015 | 88 | 2015 |
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms M Ostaszewski, A Niarakis, A Mazein, I Kuperstein, R Phair, ... Molecular systems biology 17 (10), e10387, 2021 | 84 | 2021 |
ChemChains: a platform for simulation and analysis of biochemical networks aimed to laboratory scientists T Helikar, JA Rogers BMC systems biology 3, 1-15, 2009 | 75 | 2009 |
Building digital twins of the human immune system: toward a roadmap R Laubenbacher, A Niarakis, T Helikar, G An, B Shapiro, RS Malik-Sheriff, ... NPJ digital medicine 5 (1), 64, 2022 | 69 | 2022 |
Automated inference of Boolean models from molecular interaction maps using CaSQ SS Aghamiri, V Singh, A Naldi, T Helikar, S Soliman, A Niarakis Bioinformatics 36 (16), 4473-4482, 2020 | 64 | 2020 |
A comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cells T Helikar, N Kochi, B Kowal, M Dimri, M Naramura, SM Raja, V Band, ... PloS one 8 (4), e61757, 2013 | 52 | 2013 |
Integrating Interactive Computational Modeling in Biology Curricula T Helikar, CE Cutucache, LA Dahlquist, TA Herek, JJ Larson, JA Rogers PLoS Computational Biology, 2015 | 51 | 2015 |
Boolean modeling of biochemical networks T Helikar, N Kochi, J Konvalina, J A Rogers The Open Bioinformatics Journal 5 (1), 2011 | 45 | 2011 |
Simulation of stimulation: cytokine dosage and cell cycle crosstalk driving timing-dependent T cell differentiation M Barberis, T Helikar, P Verbruggen Frontiers in physiology 9, 879, 2018 | 43 | 2018 |
A Mechanistic Computational Model Reveals That Plasticity of CD4+ T Cell Differentiation Is a Function of Cytokine Composition and Dosage BL Puniya, RG Todd, A Mohammed, DM Brown, M Barberis, T Helikar Frontiers in physiology 9, 878, 2018 | 40 | 2018 |
Student understanding of DNA structure–function relationships improves from using 3D learning modules with dynamic 3D printed models ME Howell, CS Booth, SM Sikich, T Helikar, RL Roston, BA Couch, ... Biochemistry and Molecular Biology Education 47 (3), 303-317, 2019 | 39 | 2019 |
A cell simulator platform: the cell collective T Helikar, B Kowal, JA Rogers Clinical Pharmacology & Therapeutics 93 (5), 393-395, 2013 | 39 | 2013 |
Recent applications of quantitative systems pharmacology and machine learning models across diseases SS Aghamiri, R Amin, T Helikar Journal of pharmacokinetics and pharmacodynamics, 1-19, 2022 | 35 | 2022 |
Dynamics of Influenza Virus and Human Host Interactions During Infection and Replication Cycle A Madrahimov, T Helikar, B Kowal, G Lu, J Rogers Bulletin of Mathematical Biology, 2012 | 35 | 2012 |