Overflow metabolism in Escherichia coli results from efficient proteome allocation M Basan, S Hui, H Okano, Z Zhang, Y Shen, JR Williamson, T Hwa Nature 528 (7580), 99-104, 2015 | 674 | 2015 |
Coordination of bacterial proteome with metabolism by cyclic AMP signalling C You, H Okano, S Hui, Z Zhang, M Kim, CW Gunderson, YP Wang, ... Nature 500 (7462), 301-306, 2013 | 440 | 2013 |
Reduction of translating ribosomes enables Escherichia coli to maintain elongation rates during slow growth X Dai, M Zhu, M Warren, R Balakrishnan, V Patsalo, H Okano, ... Nature microbiology 2 (2), 1-9, 2016 | 283 | 2016 |
The innate growth bistability and fitness landscapes of antibiotic-resistant bacteria JB Deris, M Kim, Z Zhang, H Okano, R Hermsen, A Groisman, T Hwa Science 342 (6162), 1237435, 2013 | 218 | 2013 |
A universal trade-off between growth and lag in fluctuating environments M Basan, T Honda, D Christodoulou, M Hörl, YF Chang, E Leoncini, ... Nature 584 (7821), 470-474, 2020 | 158 | 2020 |
A growth‐rate composition formula for the growth of E. coli on co‐utilized carbon substrates R Hermsen, H Okano, C You, N Werner, T Hwa Molecular systems biology 11 (4), 801, 2015 | 114 | 2015 |
Need‐based activation of ammonium uptake in Escherichia coli M Kim, Z Zhang, H Okano, D Yan, A Groisman, T Hwa Molecular systems biology 8 (1), 616, 2012 | 97 | 2012 |
From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions M Mori, Z Zhang, A Banaei‐Esfahani, JB Lalanne, H Okano, BC Collins, ... Molecular systems biology 17 (5), e9536, 2021 | 89 | 2021 |
Regulation underlying hierarchical and simultaneous utilization of carbon substrates by flux sensors in Escherichia coli H Okano, R Hermsen, K Kochanowski, T Hwa Nature microbiology 5 (1), 206-215, 2020 | 62 | 2020 |
Slowdown of Translational Elongation in Escherichia coli under Hyperosmotic Stress X Dai, M Zhu, M Warren, R Balakrishnan, H Okano, JR Williamson, ... MBio 9 (1), 10.1128/mbio. 02375-17, 2018 | 61 | 2018 |
Complementing yeast rho1 mutation groups with distinct functional defects A Saka, M Abe, H Okano, M Minemura, H Qadota, T Utsugi, A Mino, ... Journal of Biological Chemistry 276 (49), 46165-46171, 2001 | 48 | 2001 |
Mathematical description of gene regulatory units RJ Tanaka, H Okano, H Kimura Biophysical journal 91 (4), 1235-1247, 2006 | 47 | 2006 |
Global coordination of metabolic pathways in Escherichia coli by active and passive regulation K Kochanowski, H Okano, V Patsalo, J Williamson, U Sauer, T Hwa Molecular systems biology 17 (4), e10064, 2021 | 41 | 2021 |
Importance of phenylalanine residues of yeast calmodulin for target binding and activation H Okano, MS Cyert, Y Ohya Journal of Biological Chemistry 273 (41), 26375-26382, 1998 | 38 | 1998 |
Augmentation by calmodulin of ADP-ribosylation factor-stimulated phospholipase D activity in permeabilized rabbit peritoneal neutrophils. K Takahashi, K Tago, H Okano, Y Ohya, T Katada, Y Kanaho Journal of immunology (Baltimore, Md.: 1950) 156 (3), 1229-1234, 1996 | 26 | 1996 |
Reversible adenylylation of glutamine synthetase is dynamically counterbalanced during steady-state growth of Escherichia coli H Okano, T Hwa, P Lenz, D Yan Journal of molecular biology 404 (3), 522-536, 2010 | 21 | 2010 |
Enzyme expression kinetics by Escherichia coli during transition from rich to minimal media depends on proteome reserves C Wu, M Mori, M Abele, A Banaei-Esfahani, Z Zhang, H Okano, ... Nature microbiology 8 (2), 347-359, 2023 | 12 | 2023 |
Hierarchical and simultaneous utilization of carbon substrates: mechanistic insights, physiological roles, and ecological consequences H Okano, R Hermsen, T Hwa Current opinion in microbiology 63, 172-178, 2021 | 11 | 2021 |
Stochastic approach to molecular interactions and computational theory of metabolic and genetic regulations H Kimura, H Okano, RJ Tanaka Journal of theoretical biology 248 (4), 590-607, 2007 | 9 | 2007 |
Reconstructing the single-cell-level behavior of a toggle switch from population-level measurements H Tozaki, TJ Kobayashi, H Okano, R Yamamoto, K Aihara, H Kimura FEBS letters 582 (7), 1067-1072, 2008 | 8 | 2008 |