Viral immune evasion due to persistence of activated T cells without effector function AJ Zajac, JN Blattman, K Murali-Krishna, DJD Sourdive, M Suresh, ... The Journal of experimental medicine 188 (12), 2205-2213, 1998 | 2412 | 1998 |
Molecular signature of CD8+ T cell exhaustion during chronic viral infection EJ Wherry, SJ Ha, SM Kaech, WN Haining, S Sarkar, V Kalia, ... Immunity 27 (4), 670-684, 2007 | 2352 | 2007 |
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment EJ Wherry, JN Blattman, K Murali-Krishna, R Van Der Most, R Ahmed Journal of virology 77 (8), 4911-4927, 2003 | 1939 | 2003 |
Cancer immunotherapy: a treatment for the masses JN Blattman, PD Greenberg Science 305 (5681), 200-205, 2004 | 888 | 2004 |
Estimating the precursor frequency of naive antigen-specific CD8 T cells JN Blattman, R Antia, DJD Sourdive, X Wang, SM Kaech, ... The Journal of experimental medicine 195 (5), 657-664, 2002 | 825 | 2002 |
Antigen-independent memory CD8 T cells do not develop during chronic viral infection EJ Wherry, DL Barber, SM Kaech, JN Blattman, R Ahmed Proceedings of the National Academy of Sciences 101 (45), 16004-16009, 2004 | 646 | 2004 |
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo JN Blattman, JM Grayson, EJ Wherry, SM Kaech, KA Smith, R Ahmed Nature medicine 9 (5), 540-547, 2003 | 479 | 2003 |
Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection H Shin, SD Blackburn, JN Blattman, EJ Wherry The Journal of experimental medicine 204 (4), 941-949, 2007 | 331 | 2007 |
Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5 Y Zhang, JN Blattman, NJ Kennedy, J Duong, T Nguyen, Y Wang, ... Nature 430 (7001), 793-797, 2004 | 314 | 2004 |
TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes D Chowell, S Krishna, PD Becker, C Cocita, J Shu, X Tan, PD Greenberg, ... Proceedings of the National Academy of Sciences 112 (14), E1754-E1762, 2015 | 240 | 2015 |
Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens F Wegmann, KH Gartlan, AM Harandi, SA Brinckmann, M Coccia, ... Nature biotechnology 30 (9), 883-888, 2012 | 222 | 2012 |
Estimating the diversity, completeness, and cross-reactivity of the T cell repertoire VI Zarnitsyna, BD Evavold, LN Schoettle, JN Blattman, R Antia Frontiers in immunology 4, 485, 2013 | 218 | 2013 |
Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction WY Ho, JN Blattman, ML Dossett, C Yee, PD Greenberg Cancer cell 3 (5), 431-437, 2003 | 218 | 2003 |
Combination immunotherapy with α-CTLA-4 and α-PD-L1 antibody blockade prevents immune escape and leads to complete control of metastatic osteosarcoma DM Lussier, JL Johnson, P Hingorani, JN Blattman Journal for immunotherapy of cancer 3, 1-11, 2015 | 212 | 2015 |
Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state A Schietinger, JJ Delrow, RS Basom, JN Blattman, PD Greenberg Science 335 (6069), 723-727, 2012 | 212 | 2012 |
Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection JN Blattman, DJD Sourdive, K Murali-Krishna, R Ahmed, JD Altman The Journal of Immunology 165 (11), 6081-6090, 2000 | 199 | 2000 |
Enhanced T-cell immunity to osteosarcoma through antibody blockade of PD-1/PD-L1 interactions DM Lussier, L O’Neill, LM Nieves, MS McAfee, SA Holechek, AW Collins, ... Journal of Immunotherapy 38 (3), 96-106, 2015 | 193 | 2015 |
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection JN Blattman, EJ Wherry, SJ Ha, RG Van Der Most, R Ahmed Journal of virology 83 (9), 4386-4394, 2009 | 182 | 2009 |
Restoration of CD28 Expression in CD28− CD8+ Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production MS Topp, SR Riddell, Y Akatsuka, MC Jensen, JN Blattman, ... The Journal of experimental medicine 198 (6), 947-955, 2003 | 177 | 2003 |
Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination EJ Wherry, JN Blattman, R Ahmed Journal of virology 79 (14), 8960-8968, 2005 | 151 | 2005 |