关注
Dan Xia
Dan Xia
Harvard Medical School
在 chgr.mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge
AA Nugent, K Lin, B Van Lengerich, S Lianoglou, L Przybyla, SS Davis, ...
Neuron 105 (5), 837-854. e9, 2020
4402020
Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer’s disease
D Xia, H Watanabe, B Wu, SH Lee, Y Li, E Tsvetkov, VY Bolshakov, ...
Neuron 85 (5), 967-981, 2015
2622015
Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region
K Schlepckow, KM Monroe, G Kleinberger, L Cantuti‐Castelvetri, ...
EMBO molecular medicine 12 (4), e11227, 2020
1902020
A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models
B van Lengerich, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, ...
Nature neuroscience 26 (3), 416-429, 2023
822023
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia
D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ...
Molecular neurodegeneration 17 (1), 41, 2022
412022
Loss of Aβ43 production caused by presenilin-1 mutations in the knockin mouse brain
D Xia, RJ Kelleher, J Shen
Neuron 90 (2), 417-422, 2016
402016
The Flightless I Homolog, fli-1, Regulates Anterior/Posterior Polarity, Asymmetric Cell Division and Ovulation During Caenorhabditis elegans Development
H Deng, D Xia, B Fang, H Zhang
Genetics 177 (2), 847-860, 2007
392007
The C. elegans CBFβ homolog, BRO-1, regulates the proliferation, differentiation and specification of the stem cell-like seam cell lineages
D Xia, Y Zhang, X Huang, Y Sun, H Zhang
Developmental biology 309 (2), 259-272, 2007
362007
Familial frontotemporal dementia-associated presenilin-1 c. 548G> T mutation causes decreased mRNA expression and reduced presenilin function in knock-in mice
H Watanabe, D Xia, T Kanekiyo, RJ Kelleher, J Shen
Journal of Neuroscience 32 (15), 5085-5096, 2012
262012
Fibrillar Aβ causes profound microglial metabolic perturbations in a novel APP knock-in mouse model
D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ...
bioRxiv, 2021.01. 19.426731, 2021
82021
The temporally regulated transcription factor sel-7 controls developmental timing in C. elegans
D Xia, X Huang, H Zhang
Developmental biology 332 (2), 246-257, 2009
72009
Quantitative Bioimaging of Microglial Response to Brain-Targeted Treatment Using Deep Learning Based Morphometry
D Joy, D Xia, K Monroe, P Sanchez, M Calvert
Microscopy and Microanalysis 28 (S1), 1422-1423, 2022
2022
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