Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease C Tufarelli, JAS Stanley, D Garrick, JA Sharpe, H Ayyub, WG Wood, ... Nature genetics 34 (2), 157-165, 2003 | 662 | 2003 |
Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the α globin cluster J Flint, C Tufarelli, J Peden, K Clark, RJ Daniels, R Hardison, W Miller, ... Human Molecular Genetics 10 (4), 371-382, 2001 | 210 | 2001 |
DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease DM Jeziorska, RJS Murray, M De Gobbi, R Gaentzsch, D Garrick, H Ayyub, ... Proceedings of the National Academy of Sciences 114 (36), E7526-E7535, 2017 | 176 | 2017 |
CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of … AJ Van Wijnen, MF van Gurp, MC De Ridder, C Tufarelli, TJ Last, ... Proceedings of the National Academy of Sciences 93 (21), 11516-11521, 1996 | 156 | 1996 |
Repressor Activity of CCAAT Displacement Protein in HL-60 Myeloid Leukemia Cells (∗) PMJ Lievens, JJ Donady, C Tufarelli, EJ Neufeld Journal of Biological chemistry 270 (21), 12745-12750, 1995 | 135 | 1995 |
Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter HA Cruickshanks, C Tufarelli Genomics 94 (6), 397-406, 2009 | 120 | 2009 |
Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16 RJ Daniels, JF Peden, C Lloyd, SW Horsley, K Clark, C Tufarelli, ... Human molecular genetics 10 (4), 339-352, 2001 | 118 | 2001 |
Knockdown of microRNA-21 inhibits proliferation and increases cell death by targeting programmed cell death 4 (PDCD4) in pancreatic ductal adenocarcinoma I Bhatti, A Lee, V James, RI Hall, JN Lund, C Tufarelli, DN Lobo, M Larvin Journal of Gastrointestinal Surgery 15 (1), 199-208, 2011 | 113 | 2011 |
Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation CP Stanley, WH Hind, C Tufarelli, SE O'Sullivan Cardiovascular research 107 (4), 568-578, 2015 | 110 | 2015 |
Endocannabinoids modulate human blood–brain barrier permeability in vitro WH Hind, C Tufarelli, M Neophytou, SI Anderson, TJ England, ... British journal of pharmacology 172 (12), 3015-3027, 2015 | 106 | 2015 |
The Janus-like role of proline metabolism in cancer L Burke, I Guterman, R Palacios Gallego, RG Britton, D Burschowsky, ... Cell death discovery 6 (1), 104, 2020 | 85 | 2020 |
Deletion of the mouse α-globin regulatory element (HS− 26) has an unexpectedly mild phenotype E Anguita, JA Sharpe, JA Sloane-Stanley, C Tufarelli, DR Higgs, ... Blood, The Journal of the American Society of Hematology 100 (10), 3450-3456, 2002 | 74 | 2002 |
Inflammation and MiR-21 pathways functionally interact to downregulate PDCD4 in colorectal cancer O Peacock, AC Lee, F Cameron, R Tarbox, N Vafadar-Isfahani, C Tufarelli, ... PloS one 9 (10), e110267, 2014 | 72 | 2014 |
Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer HA Cruickshanks, N Vafadar-Isfahani, DS Dunican, A Lee, D Sproul, ... Nucleic acids research 41 (14), 6857-6869, 2013 | 69 | 2013 |
Identification of a novel mutation disrupting the DNA binding activity of GCM2 in autosomal recessive familial isolated hypoparathyroidism L Baumber, C Tufarelli, S Patel, P King, CA Johnson, ER Maher, ... Journal of medical genetics 42 (5), 443-448, 2005 | 64 | 2005 |
Hair Defects and Pup Loss in Mice with Targeted Deletion of the First Cut Repeat Domain of theCux/CDPHomeoprotein Gene C Tufarelli, Y Fujiwara, DC Zappulla, EJ Neufeld Developmental biology 200 (1), 69-81, 1998 | 61 | 1998 |
α-Thalassemia resulting from a negative chromosomal position effect VM Barbour, C Tufarelli, JA Sharpe, ZE Smith, H Ayyub, CA Heinlein, ... Blood, The Journal of the American Society of Hematology 96 (3), 800-807, 2000 | 60 | 2000 |
CASP, a novel, highly conserved alternative-splicing product of the CDP/cut/cux gene, lacks cut-repeat and homeo DNA-binding domains, and interacts with full-length CDP in vitro PMJ Lievens, C Tufarelli, JJ Donady, A Stagg, EJ Neufeld Gene 197 (1-2), 73-81, 1997 | 47 | 1997 |
Social epigenetics: a science of social science? E Chung, J Cromby, D Papadopoulos, C Tufarelli The Sociological Review 64 (1_suppl), 168-185, 2016 | 46 | 2016 |
Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human α-globin domain C Tufarelli, AM Frischauf, R Hardison, J Flint, DR Higgs Genomics 71 (3), 307-314, 2001 | 38 | 2001 |