Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK–STAT signaling pathway MA Meraz, JM White, KCF Sheehan, EA Bach, SJ Rodig, AS Dighe, ... Cell 84 (3), 431-442, 1996 | 2071 | 1996 |
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses SJ Rodig, MA Meraz, JM White, PA Lampe, JK Riley, CD Arthur, KL King, ... Cell 93 (3), 373-383, 1998 | 1125 | 1998 |
Persistent LCMV infection is controlled by blockade of type I interferon signaling JR Teijaro, C Ng, AM Lee, BM Sullivan, KCF Sheehan, M Welch, ... Science 340 (6129), 207-211, 2013 | 881 | 2013 |
A critical function for type I interferons in cancer immunoediting GP Dunn, AT Bruce, KCF Sheehan, V Shankaran, R Uppaluri, JD Bui, ... Nature immunology 6 (7), 722-729, 2005 | 734 | 2005 |
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice SL Erickson, FJ De Sauvage, K Kikly, K Carver-Moore, S Pitts-Meek, ... Nature 372 (6506), 560-563, 1994 | 725 | 1994 |
MHC-II neoantigens shape tumour immunity and response to immunotherapy E Alspach, DM Lussier, AP Miceli, I Kizhvatov, M DuPage, AM Luoma, ... Nature 574 (7780), 696-701, 2019 | 674 | 2019 |
Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors. KC Sheehan, NH Ruddle, RD Schreiber Journal of immunology (Baltimore, Md.: 1950) 142 (11), 3884-3893, 1989 | 515 | 1989 |
Type I IFN contributes to NK cell homeostasis, activation, and antitumor function JB Swann, Y Hayakawa, N Zerafa, KCF Sheehan, B Scott, RD Schreiber, ... The Journal of Immunology 178 (12), 7540-7549, 2007 | 380 | 2007 |
High-dimensional analysis delineates myeloid and lymphoid compartment remodeling during successful immune-checkpoint cancer therapy MM Gubin, E Esaulova, JP Ward, ON Malkova, D Runci, P Wong, ... Cell 175 (4), 1014-1030. e19, 2018 | 369 | 2018 |
Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity JE Fenner, R Starr, AL Cornish, JG Zhang, D Metcalf, RD Schreiber, ... Nature immunology 7 (1), 33-39, 2006 | 367 | 2006 |
Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction DK Wells, MM van Buuren, KK Dang, VM Hubbard-Lucey, KCF Sheehan, ... Cell 183 (3), 818-834. e13, 2020 | 359 | 2020 |
Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice. GJ Bancroft, KC Sheehan, RD Schreiber, ER Unanue Journal of immunology (Baltimore, Md.: 1950) 143 (1), 127-130, 1989 | 336 | 1989 |
Cytokine‐related syndrome following injection of anti‐CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation C Ferran, K Sheehan, M Dy, R Schreiber, S Merite, P Landais, LH Noel, ... European journal of immunology 20 (3), 509-515, 1990 | 328 | 1990 |
Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids C Paget, T Mallevaey, AO Speak, D Torres, J Fontaine, KCF Sheehan, ... Immunity 27 (4), 597-609, 2007 | 324 | 2007 |
Blocking Monoclonal Antibodies Specific for Mouse IFN-α/β Receptor Subunit 1 (IFNAR-1) from Mice Immunized by In Vivo Hydrodynamic Transfection KCF Sheehan, KS Lai, GP Dunn, AT Bruce, MS Diamond, JD Heutel, ... Journal of interferon & cytokine research 26 (11), 804-819, 2006 | 277 | 2006 |
IFN unresponsiveness in LNCaP cells due to the lack of JAK1 gene expression GP Dunn, KCF Sheehan, LJ Old, RD Schreiber Cancer research 65 (8), 3447-3453, 2005 | 211 | 2005 |
Cutting edge: IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation A Krug, R Uppaluri, F Facchetti, BG Dorner, KCF Sheehan, RD Schreiber, ... The Journal of Immunology 169 (11), 6079-6083, 2002 | 199 | 2002 |
Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75. KC Sheehan, JK Pinckard, CD Arthur, LP Dehner, DV Goeddel, ... The Journal of experimental medicine 181 (2), 607-617, 1995 | 197 | 1995 |
Blockade of interferon Beta, but not interferon alpha, signaling controls persistent viral infection CT Ng, BM Sullivan, JR Teijaro, AM Lee, M Welch, S Rice, KCF Sheehan, ... Cell host & microbe 17 (5), 653-661, 2015 | 184 | 2015 |
Baculovirus stimulates antiviral effects in mammalian cells AM Gronowski, DM Hilbert, KCF Sheehan, G Garotta, RD Schreiber Journal of virology 73 (12), 9944-9951, 1999 | 176 | 1999 |