Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro W Colon, JW Kelly Biochemistry 31 (36), 8654-8660, 1992 | 691 | 1992 |
The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid Z Lai, W Colón, JW Kelly Biochemistry 35 (20), 6470-6482, 1996 | 678 | 1996 |
Kinetic role of early intermediates in protein folding H Roder, W Colón Current opinion in structural biology 7 (1), 15-28, 1997 | 406 | 1997 |
Structural basis of protein kinetic stability: resistance to sodium dodecyl sulfate suggests a central role for rigidity and a bias toward β-sheet structure M Manning, W Colón Biochemistry 43 (35), 11248-11254, 2004 | 288 | 2004 |
Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease SL McCutchen, Z Lai, GJ Miroy, JW Kelly, W Colon Biochemistry 34 (41), 13527-13536, 1995 | 248 | 1995 |
Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity SL McCutchen, W Colon, JW Kelly Biochemistry 32 (45), 12119-12127, 1993 | 245 | 1993 |
Cytochrome c on Silica Nanoparticles: Influence of Nanoparticle Size on Protein Structure, Stability, and Activity W Shang, JH Nuffer, VA Muñiz‐Papandrea, W Colón, RW Siegel, ... Small 5 (4), 470-476, 2009 | 236 | 2009 |
Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid JW Kelly, W Colon, Z Lai, HA Lashuel, J Mcculloch, SL Mccutchen, ... Advances in protein chemistry 50, 161-181, 1997 | 231 | 1997 |
Identification of the predominant non-native histidine ligand in unfolded cytochrome c W Colón, LP Wakem, F Sherman, H Roder Biochemistry 36 (41), 12535-12541, 1997 | 208 | 1997 |
Side chain packing of the N-and C-terminal helices plays a critical role in the kinetics of cytochrome c folding W Colón, GA Elöve, LP Wakem, F Sherman, H Roder Biochemistry 35 (17), 5538-5549, 1996 | 197 | 1996 |
Kinetic intermediates in the formation of the cytochrome c molten globule W Colon, H Roderlr Nature structural biology 3 (12), 1996 | 138 | 1996 |
Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS KA Vassall, HR Stubbs, HA Primmer, MS Tong, SM Sullivan, R Sobering, ... Proceedings of the National Academy of Sciences 108 (6), 2210-2215, 2011 | 123 | 2011 |
Biochemical characterization of major bone-matrix proteins using nanoscale-size bone samples and proteomics methodology GE Sroga, L Karim, W Colón, D Vashishth Molecular & Cellular Proteomics 10 (9), 2011 | 112 | 2011 |
Modification of cysteine 111 in Cu/Zn superoxide dismutase results in altered spectroscopic and biophysical properties MD de Beus, J Chung, W Colón Protein Science 13 (5), 1347-1355, 2004 | 103 | 2004 |
Kinetic stability of Cu/Zn superoxide dismutase is dependent on its metal ligands: implications for ALS SM Lynch, SA Boswell, W Colón Biochemistry 43 (51), 16525-16531, 2004 | 101 | 2004 |
Murine apolipoprotein serum amyloid A in solution forms a hexamer containing a central channel L Wang, HA Lashuel, T Walz, W Colon Proceedings of the National Academy of Sciences 99 (25), 15947-15952, 2002 | 97 | 2002 |
Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE K Xia, M Manning, H Hesham, Q Lin, C Bystroff, W Colón Proceedings of the National Academy of Sciences 104 (44), 17329-17334, 2007 | 95 | 2007 |
Dominant role of copper in the kinetic stability of Cu/Zn superoxide dismutase SM Lynch, W Colón Biochemical and Biophysical Research Communications 340 (2), 457-461, 2006 | 69 | 2006 |
Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2. 2 S Srinivasan, S Patke, Y Wang, Z Ye, J Litt, SK Srivastava, MM Lopez, ... Journal of Biological Chemistry 288 (4), 2744-2755, 2013 | 62 | 2013 |
Cu/Zn superoxide dismutase can form pore-like structures J Chung, H Yang, MD De Beus, CY Ryu, K Cho, W Colón Biochemical and biophysical research communications 312 (4), 873-876, 2003 | 60 | 2003 |