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| A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models JX Song, S Malampati, Y Zeng, SSK Durairajan, CB Yang, BCK Tong, ... Aging cell 19 (2), e13069, 2020 | 121 | 2020 |
| Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: a mechanism review ZY Wang, J Liu, Z Zhu, CF Su, SG Sreenivasmurthy, A Iyaswamy, JH Lu, ... Biomedicine & Pharmacotherapy 133, 110968, 2021 | 62 | 2021 |
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| A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38 C Yang, Z Zhu, BCK Tong, A Iyaswamy, WJ Xie, Y Zhu, ... Redox biology 32, 101445, 2020 | 47 | 2020 |
| A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro Z Wang, C Yang, J Liu, B Chun-Kit Tong, Z Zhu, S Malampati, ... International journal of molecular sciences 21 (4), 1515, 2020 | 47 | 2020 |
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| Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models A Iyaswamy, X Wang, S Krishnamoorthi, V Kaliamoorthy, ... Redox biology 51, 102280, 2022 | 44 | 2022 |
| DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway T Lu, Z Zhu, J Wu, H She, R Han, H Xu, ZH Qin Cell Communication and Signaling 17, 1-15, 2019 | 42 | 2019 |
| Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease A Iyaswamy, SK Krishnamoorthi, H Zhang, SG Sreenivasmurthy, Z Zhu, ... Phytomedicine 91, 153648, 2021 | 37 | 2021 |
| Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, S Senapati, ... Phytomedicine 96, 153887, 2022 | 36 | 2022 |
| Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease BCK Tong, AJ Wu, AS Huang, R Dong, S Malampati, A Iyaswamy, ... Autophagy 18 (3), 624-642, 2022 | 35 | 2022 |
| NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models A Iyaswamy, SK Krishnamoorthi, JX Song, CB Yang, V Kaliyamoorthy, ... Journal of food and drug analysis 28 (1), 132-146, 2020 | 32 | 2020 |
| Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies BCK Tong, AS Huang, AJ Wu, A Iyaswamy, OKY Ho, AHY Kong, ... Journal of Biomedical Science 29 (1), 85, 2022 | 26 | 2022 |
| Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, RN Reddi, ... Frontiers in Molecular Biosciences 9, 1030534, 2022 | 25 | 2022 |
| Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Z Zhu, L Liu, C Su, J Liu, BCK Tong, A Iyaswamy, S Krishnamoorthi, ... Acta Pharmacologica Sinica 43 (10), 2511-2526, 2022 | 23 | 2022 |
| Klotho an autophagy stimulator as a potential therapeutic target for Alzheimer’s disease: A review TY Fung, A Iyaswamy, SG Sreenivasmurthy, S Krishnamoorthi, XJ Guan, ... Biomedicines 10 (3), 705, 2022 | 22 | 2022 |
| TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 C Yang, J Liu, BCK Tong, Z Wang, Z Zhu, C Su, SG Sreenivasmurthy, ... Acta Pharmacologica Sinica 43 (5), 1251-1263, 2022 | 21 | 2022 |
| DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR J Geng, R Zhang, X Yuan, H Xu, Z Zhu, X Wang, Y Wang, G Xu, W Guo, ... Cell Death & Disease 11 (9), 768, 2020 | 21 | 2020 |
| NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation J Zhou, Z Zhu, F Wu, Y Zhou, R Sheng, J Wu, Z Qin Acta Pharmacologica Sinica 40 (2), 180-191, 2019 | 19 | 2019 |
