Hypothalamic orexin neurons regulate arousal according to energy balance in mice A Yamanaka, CT Beuckmann, JT Willie, J Hara, N Tsujino, M Mieda, ... Neuron 38 (5), 701-713, 2003 | 1036 | 2003 |
Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal D Georgescu, V Zachariou, M Barrot, M Mieda, JT Willie, AJ Eisch, ... Journal of Neuroscience 23 (8), 3106-3111, 2003 | 436 | 2003 |
Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice M Mieda, JT Willie, J Hara, CM Sinton, T Sakurai, M Yanagisawa Proceedings of the National Academy of Sciences 101 (13), 4649-4654, 2004 | 400 | 2004 |
The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker M Mieda, SC Williams, JA Richardson, K Tanaka, M Yanagisawa Proceedings of the National Academy of Sciences 103 (32), 12150-12155, 2006 | 334 | 2006 |
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice K Sasaki, M Suzuki, M Mieda, N Tsujino, B Roth, T Sakurai PloS one 6 (5), e20360, 2011 | 279 | 2011 |
Cellular clocks in AVP neurons of the SCN are critical for interneuronal coupling regulating circadian behavior rhythm M Mieda, D Ono, E Hasegawa, H Okamoto, K Honma, S Honma, ... Neuron 85 (5), 1103-1116, 2015 | 273 | 2015 |
Differential roles of orexin receptor-1 and-2 in the regulation of non-REM and REM sleep M Mieda, E Hasegawa, YY Kisanuki, CM Sinton, M Yanagisawa, ... Journal of Neuroscience 31 (17), 6518-6526, 2011 | 262 | 2011 |
Astrocytes regulate daily rhythms in the suprachiasmatic nucleus and behavior CF Tso, T Simon, AC Greenlaw, T Puri, M Mieda, ED Herzog Current Biology 27 (7), 1055-1061, 2017 | 253 | 2017 |
Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal T Sakurai, M Mieda Trends in pharmacological sciences 32 (8), 451-462, 2011 | 253 | 2011 |
Orexin neurons function in an efferent pathway of a food-entrainable circadian oscillator in eliciting food-anticipatory activity and wakefulness M Mieda, SC Williams, CM Sinton, JA Richardson, T Sakurai, ... Journal of Neuroscience 24 (46), 10493-10501, 2004 | 232 | 2004 |
The orexin system: roles in sleep/wake regulation T Sakurai, M Mieda, N Tsujino Annals of the New York Academy of Sciences 1200 (1), 149-161, 2010 | 220 | 2010 |
Central control of bone remodeling by neuromedin U S Sato, R Hanada, A Kimura, T Abe, T Matsumoto, M Iwasaki, H Inose, ... Nature medicine 13 (10), 1234-1240, 2007 | 210 | 2007 |
R-spondin3 is required for mouse placental development M Aoki, M Mieda, T Ikeda, Y Hamada, H Nakamura, H Okamoto Developmental biology 301 (1), 218-226, 2007 | 191 | 2007 |
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways E Hasegawa, M Yanagisawa, T Sakurai, M Mieda The Journal of clinical investigation 124 (2), 604-616, 2014 | 174 | 2014 |
Indispensability of the glutamate transporters GLAST and GLT1 to brain development TR Matsugami, K Tanemura, M Mieda, R Nakatomi, K Yamada, T Kondo, ... Proceedings of the National Academy of Sciences 103 (32), 12161-12166, 2006 | 158 | 2006 |
Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors M Mieda, M Yanagisawa Current opinion in neurobiology 12 (3), 339-345, 2002 | 150 | 2002 |
Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders: rationale for development and current status M Mieda, T Sakurai CNS drugs 27, 83-90, 2013 | 123 | 2013 |
Orexin receptor-1 in the locus coeruleus plays an important role in cue-dependent fear memory consolidation S Soya, H Shoji, E Hasegawa, M Hondo, T Miyakawa, M Yanagisawa, ... Journal of Neuroscience 33 (36), 14549-14557, 2013 | 122 | 2013 |
Disruption of Bmal1 impairs blood–brain barrier integrity via pericyte dysfunction R Nakazato, K Kawabe, D Yamada, S Ikeno, M Mieda, S Shimba, E Hinoi, ... Journal of Neuroscience 37 (42), 10052-10062, 2017 | 108 | 2017 |
Bone resorption is regulated by circadian clock in osteoblasts T Takarada, C Xu, H Ochi, R Nakazato, D Yamada, S Nakamura, ... Journal of Bone and Mineral Research 32 (4), 872-881, 2017 | 105 | 2017 |